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JP5209302B2 |
Compounds useful in modulating angiogenesis and uses thereof in methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound; and compositions for use in inhibiting angiogenesis-mediate...
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JP5207608B2 |
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JP2013095755A |
To provide a new cationic lipid to facilitate introduction of a nucleic acid into a cell, and a new composition, etc., containing the cationic lipid.The cationic lipid is expressed by formula (I) (in the formula, R1 and R2 are each alken...
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JP5172827B2 |
The invention relates to a compound of the following formula I X-CR 1 R 2 R 3 (I) wherein - R 1 is an organic moiety having 6 to 24 carbon atoms; - R 2 is H or an organic moiety having...
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JP5166668B2 |
Ionic compounds with a freezing point of up to 100° C. are formed by the reaction of an one amine salt of formula (I) R1R2R3R4N+X-, such as choline chloride with an organic compound (II) capable of forming a hydrogen bond with X; such a...
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JP5160514B2 |
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JP5154634B2 |
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JP2013023774A |
To provide a liquid softener composition that is capable of uniformly dispersing a perfume without deteriorating the dispersion system of a base softener and is capable of imparting a fresh aroma to clothing.A component (A) is one or mor...
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JP2013503206A |
Described herein are cannabidiol prodrugs used in pharmaceutical compositions as well as microneedle drug delivery systems comprising a pharmaceutical compositions comprising pharmaceutically active agents (e.g., cannabidiol and prodrugs...
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JP2012533634A |
An unsaturated quaternary ammonium salt is produced by a process that includes reacting methyl chloride in a first vessel with a stoichiometric excess of an unsaturated tertiary amine in the presence of water to form a reaction mixture t...
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JP2012252124A |
To provide a resist composition which enables production of a pattern with an excellent pattern collapse margin (PCM).A resist composition contains a compound (I) expressed by the formula (I), salt (B1) expressed by the formula (B1), a r...
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JP5090770B2 |
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JP5089265B2 |
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JP5080706B2 |
To provide a cationic surfactant or the like having excellent preservation stability and softness, and good tone of color. This cationic surfactant is characterized in that the surfactant contains (i) >=75 pts.wt. specific cationic compo...
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JP5080458B2 |
The present invention discloses compounds of formula (I), their optical isomers or pharmaceutically acceptable salts thereof, their preparation and uses thereof, wherein the definitions of R1, R2, R3 and R4 are shown in the description. ...
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JP5044059B2 |
An object of the present invention is to provide a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof and to provide a pharmaceutical agent which contains said compound as an active ingredient and has a ...
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JP5017631B2 |
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JPWO2010098023A1 |
A polymerizable monomer in which a group containing one or more polymerizable functional groups is substituted in the following formula (1). [During the ceremony, Ar1And Ar4~ Ar6Are independently substituted or unsubstituted aryl groups ...
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JP5014572B2 |
To provide a polymerizable surfactant having a high surface active function, on using as an emulsifying agent in an emulsion polymerization, requiring only a small adding amount, without leaving the used surfactant unnecessarily or witho...
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JP5007309B2 |
Disclosed are synthetic methods of formula (V) compounds: wherein R1-R7 are same or different and respectively selected from hydrogen and C1-4 alkyl; and n is an integer of 1-4. Said methods can be carried out as one-pot processes. Synth...
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JP4984587B2 |
To provide a bifunctional aqueous epoxy resin composition having excellent preservation stability, corrosion resistance, adhesion or the like, and a method for producing the cured product thereof. The aqueous epoxy resin composition cont...
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JP4965886B2 |
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JP2012514654A |
Fluorinated compounds and methods of making fluorinated compounds are described herein.
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JP4954165B2 |
To produce a labeled compound for a selected biological substance not using a radioisotope atom which has a risk of exposure to radioactivity and limitation on handling time but using a stable isotope atom; and that the labeled compound ...
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JP2012511027A |
The invention provides compositions or pharmaceutical compositions of novel high penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capabl...
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JP4928729B2 |
Diamine compounds, which in particular are useful as precursors for the production of liquid crystal alignment layers, represented by the general formula I: wherein A<1> represents an organic group of 1 to 40 carbon atoms; A<2> repre...
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JP2012509875A |
A compound having the structure wherein Y is selected from the group consisting of -C(O)OR2, -C(O)NHR8, -C(CH2)1-2OR3, OH, and or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
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JP4925547B2 |
A process for the preparation of a compound of formula (I)whereinR1 and R2 are each independently of the other C1-C8alkyl, cyclopentyl or cyclohexyl,m is 1, 2 or 3, preferably 2,n is an integer from 1 to 30, andR3 is an n-valent radical ...
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JP2012506418A |
The invention relates to compounds of Formula (I) wherein R1, R2, R3, R4, R5, m and n are as defined in the description, and to pharmaceutically acceptable salts of such compounds. These compounds are useful as calcium channel blockers.
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JP4897214B2 |
The present invention is related to an intermediate layer of an organic electroluminescent device comprising an amine derivative substance which may further comprise a functional group capable of forming crosslinks. In particular, the su...
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JP4896157B2 |
Novel cyclohexylmethyl compounds corresponding to formula I wherein R1, R2, R3, R4 and R5, have the meanings given in the description. Pharmaceutical formulations containing these compounds, as well as a processes for preparing these com...
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JP4880612B2 |
The invention relates to enantiomerically pure DOTAP chloride and stable crystal modifications of (2R,S)-, (2S)- and (2R)-DOTAP chloride, to a process for the preparation of these modifications, and to the use thereof as constituent for ...
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JP4867222B2 |
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JP2012502126A |
The present invention relates to a (meth)acrylate monomer of the general formula (I) in which R1 is hydrogen or a methyl group, X is oxygen or a group of the formula NR′ in which R′ is hydrogen or a radical having 1 to 6 carbon atoms...
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JP4860887B2 |
The present invention relates to the use of an amino compound, which is an esteramine or an amidoamine surfactant with improved biodegradability, as an adjuvant for agrochemically active compounds such as pesticides or fertilisers. The a...
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JP4853834B2 |
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JP4849374B2 |
To provide a method for producing a mixed crystal of type I crystal and type II crystal of (±)2-(dimethylamino)-1-ä[O-(m-methoxyphenethyl)phenoxy]met
hyl}ethyl hydrogen succinate hydrochloride useful as a pharmaceutical product. (±)2-...
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JP4851020B2 |
The invention provides a multistep synthesis for the preparation of 4,5-diamino shikimic acid derivatives of formula starting from an isophtalic acid derivative of formula 4,5-Diamino shikimic acid derivatives are potent inhibitors of vi...
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JP4846552B2 |
3-Phenyl-N,N-dimethyl-propylamine derivs. of formula (I) and their isomers and acid-addn. salts are new; X = H, OH, F, Cl or 2-4C alkanoyloxy; R1 = 1-4C alkyl; R2 = H or 1-4C alkyl; R3 = H or 1-4C n-alkyl; or CR2R3 = 4-7C cycloalkylidene...
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JP4846750B2 |
Dimethyl-(3-aryl-but-3-enyl)amine compounds of formula (I) and their salts, as enantiomers or racemates, are new. R1 = 1-5C alkyl; R2, R3 = H or 1-5C alkyl; or R1+R2 = (CH2)2, (CH2)3, (CH2)4, (CH2)2CHR7 or CH2-CHR7-CH2; R4, R6 = H, OH, 1...
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JP4833884B2 |
The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the inv...
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JP4809768B2 |
Polyacetals comprising a recurring units represented by a formula selected from the group consisting of formula (I) and (II): wherein A comprises at least one acetal group; B is selected from the group consisting of -CH-, -CH(CH3)-, CH2C...
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JP4812759B2 |
The invention relates to compounds corresponding to formula (I): in which: Ar represents a mono- or disubstituted phenyl; R1 represents an unsubstituted or substituted phenyl; R2 represents: a pyridyl; an unsubstituted or substituted phe...
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JP4799592B2 |
The subject-matter of the invention is the B form of ethyl [(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino]-5,6,7,
8-tetrahydronaphth-2-yloxy]acetate hydrochloride, of use as a medicament, which exhibits in particular the following ...
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JP2011207772A |
To provide a method for producing a (meth)acrylic ester by which the amount of an additionally charged catalyst can be reduced.The method for producing the (meth)acrylic ester comprises: heating a mixture of an alcohol (A), an alkyl(meth...
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JP4796607B2 |
In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): wherein R<1> and R<2> independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cycloalkyl group; or R<1> and R<...
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JP4792294B2 |
The present invention relates to a hyaluronic acid derivative in which an anti-inflammatory drug is bound via a covalent bond, wherein the structure of the hyaluronic acid derivative is represented by following formula (4) or (5): ...
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JP2011180569A |
To provide a resist composition which is excellent in storage stability and has good lithography properties, to provide a method for forming a resist pattern using the resist composition, and to provide a nitrogen-containing organic comp...
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JP4773188B2 |
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JP2011175724A |
To provide a curing composition for transfer materials, which is suitable for a nanoimprint method in which selectivity of a dry etching speed with argon gas and oxygen gas is high, and which is capable of forming a fine pattern with a h...
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