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JP2017052816A |
To provide: xanthene-based dyes excellent in solvent solubility or precursors thereof; production methods of these compounds; and recording materials, display materials and analytical chemistry reagents employing these compounds.The inve...
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JP2017036330A |
To provide a novel compound for preparation.The present invention provides a compound of formula (X) (where Rand Rare H, predetermined alkyl or alkenyl, Rand Rare predetermined alkyl, alkenyl, or alkynyl, Land Lare a predetermined linkin...
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JP6046219B2 |
The present invention relates to photoaligning material with lateral substitution, compositions thereof, and its use for optical and electro optical devices, especially liquid crystal devices (LCDs).
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JP2016188233A |
To provide polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods of preparing the same and use of the same.Provided herein is a crystal form II of 4-[2-dimethylamino-1-(1-hydroxycycl...
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JP6002153B2 |
Provided are analgesic compounds, and salts thereof, of formula: (I) wherein A is: (A) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.
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JP5976088B2 |
The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.
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JP5964180B2 |
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JP5957583B2 |
The present invention provides a method for producing a high quality cationic surfactant, which is prevented from smelling and coloring, and has favorable storage stability. The production method includes the following step 1, step 2, st...
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JP2016132656A |
To provide a method for producing dimethylamino acrylate and dimethylamino acrylate quaternary salt, in which the method does not have adverse effect on a polymer obtained by polymerizing dimethylaminoethyl acrylate or dimethylaminoethyl...
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JP5940036B2 |
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JP5939157B2 |
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JP5930975B2 |
A process is described for the preparation of 3-(5-formyl-2-hydroxyphenyl)-3-phenylpropylamine derivatives, intermediates which can be used for preparation of agents for urinary incontinence therapy, specifically to 2-(3-(diisopropylamin...
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JP2016516018A |
One mode of the present invention provides the new high penetration constituent (HPC) or high penetration prodrug (HPP) for the medical treatment of Parkinson's disease. Since HPC/HPP may be changed into parent active medicine or a drug ...
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JP5916219B2 |
To provide ionic liquid capable of improving capacity of physically absorbing acidic gas.In the ionic liquid including an ether group and/or an ester group, cations are one or more kinds of cations, which are non-cyclic or cyclic ammoniu...
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JP5916629B2 |
The invention provides a method of continuously producing high quality quaternized N,N-dialkylaminoethyl (meth)acrylates (DMAEA.MCQ) that has a long shelf life and which is stable in water. The method involves placing starting materials ...
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JP5905411B2 |
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JP5899927B2 |
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JP5902616B2 |
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I) (wherein: R 1 and R 2 are, the same or different, alkenyl, etc, and X 1 and X 2 are hydrogen atoms,...
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JP5882334B2 |
The present invention relates to a process for preparing (meth)acrylic esters (F) of N,N-substituted amino alcohols, by transesterifying N,N-substituted amino alcohols (I) in which Y and Z are each independently C1-C20-alkyl, C3-C15-cycl...
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JP5881317B2 |
To provide a chloride ion-free and metal salt-free unsaturated quaternary ammonium salt excellent in compatibility, used suitably for various electrochemical devices, and having a continuously excellent antistatic effect, and to provide ...
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JP5879817B2 |
To provide a new compound obtainable of a charge transporting film in which fluctuation of mobility is suppressed even when being used repeatedly.This reactive compound is represented by general formula (I). In the formula (I), F represe...
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JP5877553B2 |
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteri...
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JP5870111B2 |
A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
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JP5857044B2 |
The object of the present invention is a new process for the synthesis of tapentadol, both as free base and in hydrochloride form, which comprises the step of alkylation of the ketone (VII) to yield the compound (VIII), as reported in Di...
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JP5856147B2 |
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JPWO2013161984A1 |
It is a diamine characterized by being represented by the following formula (1). [Chemical 1](In equation (1), X1Is a single bond or an alkylene group having 1 to 6 carbon atoms (however, the alkylene groups are not adjacent to each othe...
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JP2015221830A |
To design and synthesize novel positively charged prodrugs of retinoids or retinoid-like compounds in a general formula (31), 'structure 31'.The positively charged amino groups of the prodrugs not only largely increase the solubility of ...
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JP2015205932A |
To provide polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods of preparing the same and use of the same.There is provided a crystal form II of 4-[2-dimethylamino-1-(1-hydroxycyclo...
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JP2015205912A |
To develop a novel compound which can be delivered effectively and efficiently to a site of action in a certain state (e.g., disease) for preventing, reducing, or treating the state in a biological subject while minimizing side effects.T...
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JP2015189680A |
To provide an unsaturated quaternary ammonium salt with high purity including no halogen in the molecule, high in safety, harmless in the environment, including no moisture, also excellent in dissolubility to water, organic solvents, con...
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JP2015180740A |
To provide a wood coating agent, a dental composite and a curable composition which comprise a polymerizable ionic liquid exhibiting good curability in the atmosphere.A polymerizable ionic liquid comprises a cation and an aromatic carbox...
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JP5781075B2 |
A multifunctional polymerizable ionic liquid is described comprising an anion and a cationic group having at least two ethylenically unsaturated polymerizable groups, each bonded to the cationic group via a divalent non-alkyl linking gro...
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JP5763832B2 |
[Problem] Provided are an ionically bonded salt having a reactive group which improves the weather resistance of a thermoplastic resin, and a thermoplastic resin composition containing the ionically bonded salt. [Solution] An ionically b...
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JP5759672B2 |
The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared ...
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JP2015140341A |
To provide an unsaturated quaternary ammonium salt with high purity, which includes no halogen in the molecule, has high safety, is harmless to environment, includes no water, further is excellent in solubility in water, organic solvents...
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JP5729458B2 |
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JP2015091842A |
To provide an amine derivative useful for treatment of eye diseases and disorders, e.g. age-related macular degeneration and Stargardt Disease, and a pharmaceutical composition using the same.There are provided an amine derivative repres...
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JP5717824B2 |
N,N-Diisopropyl-3-(2-acyloxy-5-hydroxymethyl)-3-phenylpropyl
ammonium salts (I) are new. Diphenylpropylamine derivative salts of formula (I) are new. [Image] R : 1-6C alkyl, 3-10C cycloalkyl or optionally substituted phenyl; X -> : resid...
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JPWO2013115040A1 |
A secondary battery including a negative electrode having a negative electrode active material and an electrolytic solution, wherein the negative electrode active material contains silicon, and the electrolytic solution contains a conjug...
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JP5714008B2 |
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JP5700578B2 |
The invention relates to a process for obtaining 3,3-diphenylpropylamines of general formula (I), particularly Fesoterodine, as well as their enantiomers, solvates and salts, comprising a chemoselective reduction of the acid group agains...
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JPWO2013065825A1 |
The present invention facilitates the introduction of nucleic acids into cells, formula (I) (in formula, R).1And R2Are the same or different, such as alkenyl, X1And X2Is a hydrogen atom or together to form a single bond or alkylene, X3Is...
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JP5684797B2 |
A method and apparatus for preparing a N,N-dialkylaminoalkyl acrytate in a continuous transesterification reaction. The reaction involves adding alkyl acrylates such as methacrylate or ethacrylate to a reboiler mechanism and efficiently ...
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JP2015012189A |
To provide a forming agent which makes it possible to form a patterned organic semiconductor compound-containing layer by a simple and convenient method at low cost without using a mask or a bank.An agent for forming a patterned organic ...
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JP5650924B2 |
N,N-Diisopropyl-3-(2-acyloxy-5-hydroxymethyl)-3-phenylpropyl
ammonium salts (I) are new. Diphenylpropylamine derivative salts of formula (I) are new. [Image] R : 1-6C alkyl, 3-10C cycloalkyl or optionally substituted phenyl; X -> : resid...
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JP5629745B2 |
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JP5620820B2 |
An antitumor agent which is not easily excreted from tumor cells and is suitable for a topical treatment. Specifically disclosed is a rotaxane compound with contains a compound represented by chemical formula 1 as the base structure. (In...
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JP2014205668A |
To provide a method for synthesizing an acrylic acid ester using, as a main ingredient, glycerin originating from a biomaterial.A method for synthesizing an acrylic acid ester expressed by CH=CH-COO-R (R is an alkyl group including 1-18 ...
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JP5594775B2 |
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JP2014172826A |
To provide a compound that, when included in a lubricating oil, can enhance longevity of shudder prevention, as well as gear-shift characteristics and torque transmission capacity, all to satisfactory levels.The invention provides a mono...
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