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Patent Searching and Data


Matches 301 - 350 out of 7,408

Document Document Title
WO/2010/011548A1
The present invention is directed to novel substituted sulfamide derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives form in the treatment of anxiety and related disorders; bipolar depress...  
WO/2010/008776A3
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/008776A2
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/008776A9
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/003624A3
Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, ...  
WO/2010/003299A1
An organic compound and preparation method thereof, particularly a flavor enhancer and preparation method thereof, are disclosed. Its chemical name is 4-isopropyl-5,5-dimethyl-m-dioxan-2-one. It is prepared by the following method: start...  
WO/2010/003624A2
Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, ...  
WO/2010/000193A1
The invention provides a process for preparing osemozotan and its pharmaceutically acceptable salts. The invention also provides an intermediate, (2R)-N-[3-(1,3- benzodioxol-5-yloxy)propyl]-1,4-benzodioxin-2-formamide, used in the proces...  
WO/2009/153886A1
A process for producing an α-hydroxy acid that is economically advantageous without the secondary production of a large volume of waste, having satisfactory quality as a polymer raw material. The process for producing an α-hydroxy acid...  
WO/2009/150248A1
The present invention relates to a compound of general formula (I) : and also to the pharmaceutically acceptable salts thereof, to the isomers or isomer mixtures thereof in all proportions, in particular to an enantiomer mixture, and esp...  
WO/2009/150966A1
Disclosed is a liquid crystalline compound which is stable against heat, light or the like and has a nematic phase in a wide temperature range, while having a low viscosity, a large optical anisotropy, an adequate elastic constant K33, a...  
WO/2009/150963A1
Disclosed is a liquid crystal compound having general physical properties necessary for a compound, stability against heat, light or the like, a wide temperature range of a liquid crystal phase, a high clearing point, good compatibility ...  
WO/2009/147632A3
The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza- undecane-2,4,8,10-tetraol.  
WO/2009/143178A3
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Hu...  
WO/2009/133109A1
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention re...  
WO/2009/133110A1
The present invention relates to novel1-(4H-1,3-benzodioxin-2-yl)methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically asdopaminergic stabilizers. In other aspects the invention relates to the...  
WO/2009/133107A1
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)- methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention r...  
WO/2009/130422A3
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/130422A2
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/129726A1
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds ...  
WO/2009/128521A1
Disclosed are: a compound having an excellent inhibitory activity on cysteine protease; and a pharmaceutical agent for the treatment or prevention of a disease selected from the group consisting of osteoporosis, osteoarthrosis deformans,...  
WO/2009/120191A1
The present invention is directed to a process for the preparation of benzo-fused heteroaryl sulfamates, useful for the treatment of epilepsy and related disorders according to formula (IA) and to a crystalline compound of formula (I-S)....  
WO/2009/120192A2
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/117829A1
Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods ...  
WO/2009/117902A1
Provided herein are 5-demethoxyfumagillol and its derivatives. Also provided herein are methods of making the 5-demethoxyfumagillol and derivatives. Also provided herein are biological activities of the 5-demethoxyfumagillol and derivati...  
WO/2009/120192A3
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/111830A1
The present invention relates to a class of conjugated unsaturated compounds, to a method of preparing such compounds, and to the polymerisation and bio-active uses of such compounds including their use as antimicrobial agents. The inven...  
WO/2009/104722A1
Provided are 1) polymer compounds having excellent acid reactivity and thermal stability as well as minimal swelling during development, 2) compounds of the following formula that serve as starting materials for said polymer compounds, a...  
WO/2009/089210A1
The present invention is directed to novel processes for the preparation of sulfamide derivatves, useful in the treatment of epilepsy and related disorders.  
WO/2009/084773A2
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/084773A3
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/080834A1
Process for the synthesis of a cyclic diester of an alpha-hydroxyacid, comprising the following steps: an alkalino-earth salt of the corresponding alpha-hydroxyacid is mixed with said alpha-hydroxyacid and water; the mixture is treated b...  
WO/2009/077385A1
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...  
WO/2009/077615A1
The present invention relates to a method for obtaining lactide by thermal cracking of lactic acid oligomers in the presence of a metal salt of the phosphite anion (PO3)3- in which the metal is chosen from the group comprising tin, alumi...  
WO/2009/075818A1
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.  
WO/2009/076618A3
The present invention relates to, in part, novel sulfate and bisphenol compounds useful for the recognition, attachment and growth of unwanted biologies on natural and manmade surfaces. Another aspect of the invention relates to combinat...  
WO/2009/070910A2
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072502A1
Disclosed is a method by which various fluorine-containing carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a fluorin...  
WO/2009/070910A3
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072501A1
Disclosed is a novel method by which various carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a compound having a car...  
WO/2009/062224A1
The invention relates to a method for producing L,L-, D,D-, D,L- or meso-dilactide, comprising polycondensation and/or polytransesterification of L-, D- or D,L-lactic acid or esters thereof to form high-molecular-weight polyesters of L-,...  
WO/2009/065035A1
The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders, such as cancer.  
WO/2009/064031A1
There is provided a compound having an excellent controlling effect on pests, represented by the formula (I): wherein, A and E independently represent a -R1 group, a -L1-R1 group, etc.; G represents a -L2-R1 group, a -S(O)2-R4 group, etc...  
WO/2009/060832A9
Disclosed is a means for producing lactide efficiently in the production of a poly(lactic acid) by depolymerizing a lactic acid oligomer to produce lactide and ring-opening-polymerizing lactide. Also disclosed is a lactide production app...  
WO/2009/060832A1
Disclosed is a means for producing lactide efficiently in the production of a poly(lactic acid) by depolymerizing a lactic acid oligomer to produce lactide and ring-opening-polymerizing lactide. Also disclosed is a lactide production app...  
WO/2009/053250A1
The invention relates to compounds of the formula (I), in which the substituents have the meanings given in the description, method for producing said compounds, agents comprising the same, and the use thereof to combat damaging fungi.  
WO/2009/035951A2
Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and co...  
WO/2009/035951A3
Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and co...  
WO/2009/031437A1
Disclosed is a liquid crystalline compound which has stability to heat, light and the like, exhibits a nematic phase in a wide temperature range, has a low viscosity, adequate optical anisotropy and an adequate elastic coefficient K33, a...  
WO/2009/030396A1
The present invention relates to a method for the production or purification of biodegradable, intramolecular cyclic esters of alpha-hydroxycarboxylic acids, biodegradable alpha-hydroxycarboxylic acids or oligopolymers or polymers thereo...  

Matches 301 - 350 out of 7,408