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Matches 301 - 350 out of 3,567

Document Document Title
WO/2007/148975
The invention relates to a method for the purification or recovery of lactide rich streams by the combination of a suspension-based melt crystallization process with a subsequent separation of the pure lactide crystals in a wash column.  
WO/2007/148975
The invention relates to a method for the purification or recovery of lactide rich streams by the combination of a suspension-based melt crystallization process with a subsequent separation of the pure lactide crystals in a wash column.  
WO/2007/139062
[PROBLEMS] To provide a prophylactic and therapeutic agent for obesity which has a more effective and potent efficacy and has reduced adverse side-effects, and also provide a method for prevention and treatment of obesity. [MEANS FOR SOL...  
WO/2007/138485
1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections.  
WO/2007/138485
1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections.  
WO/2007/139998
The present invention provides methods for preparing a compound of formula D having activity as dopamine autoreceptor agonist and partial agonists at the postsynaptic dopamine D2 receptor. This compound is useful for treating dopaminergi...  
WO/2007/139998
The present invention provides methods for preparing a compound of formula D having activity as dopamine autoreceptor agonist and partial agonists at the postsynaptic dopamine D2 receptor. This compound is useful for treating dopaminergi...  
WO/2007/136790
Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.  
WO/2007/136790
Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.  
WO/2007/133751
A stabilized semi-solid delivery vehicle contains a polyorthoester and an excipient, and a pharmaceutical composition contains an active agent, optionally a stabilizing agent, and the delivery vehicle. The pharmaceutical composition may ...  
WO/2007/133751
A stabilized semi-solid delivery vehicle contains a polyorthoester and an excipient, and a pharmaceutical composition contains an active agent, optionally a stabilizing agent, and the delivery vehicle. The pharmaceutical composition may ...  
WO/2007/127309
Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.  
WO/2007/127309
Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.  
WO/2007/123942
The present invention relates to methods for synthesizing compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein each of R1, R2, R3, R4, x, m, n, and Ar are as defined, and described in classes and sub...  
WO/2007/123942
The present invention relates to methods for synthesizing compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein each of R1, R2, R3, R4, x, m, n, and Ar are as defined, and described in classes and sub...  
WO/2007/115968
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclope ntyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secr...  
WO/2007/115968
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclope ntyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secr...  
WO/2007/114213
[PROBLEMS] To provide a compound capable of inhibiting the production of a prostaglandin or leukotriene. [MEANS FOR SOLVING PROBLEMS] Disclosed is a compound represented by the general formula (I) or a salt thereof: (I) wherein (a) repre...  
WO/2007/107276
The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly...  
WO/2007/107276
The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly...  
WO/2007/099553
The present invention relates to novel 1,3-dioxane carboxylic acids of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods fo...  
WO/2007/099553
The present invention relates to novel 1,3-dioxane carboxylic acids of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods fo...  
WO/2007/096261
The present invention is concerned with a novel process for the preparation of compounds of formula (I), wherein R1 and R2 are as defined in the description and claims. The compounds of formula (I) are pharmaceutically active substances.  
WO/2007/096261
The present invention is concerned with a novel process for the preparation of compounds of formula (I), wherein R1 and R2 are as defined in the description and claims. The compounds of formula (I) are pharmaceutically active substances.  
WO/2007/083640
[PROBLEMS] To provide a drug which has a selective β3 receptor activating effect and is useful in preventing or treating increased urinary frequency and urinary incontinence. [MEANS FOR SOLVING PROBLEMS] It is disclosed that 6-[2-(R)-[(...  
WO/2007/074776
The invention aims at providing a simple and easy method by which many kinds of organic chemicals (contaminants) can be efficiently decomposed in a short time and separated and recovered as insoluble matter. Water or soil contaminated wi...  
WO/2007/069773
The present invention provides a novel modulator of the TRPV1-receptor function, comprising a compound of the formula; wherein ring A is an optionally substituted carbocycle or heterocycle, ring B is an optionally substituted benzene rin...  
WO/2007/069777
Conventional fungicidal compositions have had practical problems such that either a preventive effect or a curative effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends ...  
WO/2007/069777
Conventional fungicidal compositions have had practical problems such that either a preventive effect or a curative effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends ...  
WO/2007/068330
The present invention relates to 2-adamantylurea derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) and the use of such compounds for the treatment and prevention of m...  
WO/2007/063925
Disclosed is a novel and excellent therapeutic or prophylactic agent for nociceptive pain, neuropathic pain, cancer pain, headache, bladder dysfunction or the like, which relies on a preventive activity on capsaicin receptor VR1 activati...  
WO/2007/057703
Process for the preparation of statins, in particular atorvastatin via intermediates of Formula (1) and a process for the preparation of said intermediates.  
WO/2007/057703
Process for the preparation of statins, in particular atorvastatin via intermediates of Formula (1) and a process for the preparation of said intermediates.  
WO/2007/051762
The invention relates to a process for producing trioxane and at least one comonomer for producing (co)polymers on a trioxane basis, in which, in a first step, formaldehyde and at least one comonomer starting material are reacted in aque...  
WO/2007/052831
A compound represented by the formula (I): wherein Ar represents a group represented by the formula: (wherein Y represents methylene or an oxygen atom, R1 represents aminosulfonyl, C1-6 alkylaminosulfonyl, C1-6 alkylcarbonylamino or C1-6...  
WO/2007/048717
Methodologies for the alpha-monohalogenation of acid sensitive ketones, especially cyclic, acid-sensitive, ketalized ketones. As one approach, the ketone is reacted with a halogen donor compound, e.g., N-chlorosuccinimide, in anhydrous, ...  
WO/2007/039110
The invention relates to compounds according to formula (I) or formula (II), wherein R is H or (CHOH)nCH2OH (n= 0, 1 or 2), Sp is -CH-, -CHOH-, -(CH2)n-, -(CH=CH)n-, -(CH=CH-CH2)n,-, -(CH2)n-X-(CH2)o-, -(CH2-X)n-(CH2)o-, -(CH2)n-C(=X)-(C...  
WO/2007/039110
The invention relates to compounds according to formula (I) or formula (II), wherein R is H or (CHOH)nCH2OH (n= 0, 1 or 2), Sp is -CH-, -CHOH-, -(CH2)n-, -(CH=CH)n-, -(CH=CH-CH2)n,-, -(CH2)n-X-(CH2)o-, -(CH2-X)n-(CH2)o-, -(CH2)n-C(=X)-(C...  
WO/2007/034909
Disclosed is a (3R,5R)-7-amino-3,5-dihydroxyheptanoic acid derivative which is useful as an intermediate for a pharmaceutical. A (3R,5R)-7-amino-3,5-dihydroxyheptanoic acid derivative or a salt thereof can be produced by a process compri...  
WO/2007/032362
It is intended to provide a substituted cycloalkene derivative represented by the general formula (I) which has an action of suppressing intracellular signal transduction or cell activation caused by endotoxin and a cell response such as...  
WO/2007/027599
This invention provides compounds of Formula (I) having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according to Formula (I...  
WO/2007/015412
Disclosed is an organic electroluminescent device (organic EL device) of simple structure which is improved in luminous efficiency and sufficiently secured in driving stability. Also disclosed is a heterocyclic compound used for such an ...  
WO/2007/013201
A zinc fluorescent probe that excels in water solubility, enabling observing with high sensitivity of any change of intracellular zinc ion level ratiometrically with the use of a single excited wavelength; a process for producing the sam...  
WO/2007/010514
Therefore the present invention relates specifically to the compounds of general formula (I), in which R1 and R2, which may be identical or different, are selected from the group comprising H, -CnH2n-1, a linear or branched alkyl group h...  
WO/2007/010514
Therefore the present invention relates specifically to the compounds of general formula (I), in which R1 and R2, which may be identical or different, are selected from the group comprising H, -CnH2n-1, a linear or branched alkyl group h...  
WO/2007/000383
Biphenyl and phenyl-naphthyl compounds bearing a hydroxamic group, which are endowed with antitumour, and anti-angiogenic activity These compounds are therefore particularly useful for the treatment of drug-resistant tumours.  
WO/2006/134955
A compound represented by the general formula (1) or (100), a salt thereof or a hydrate of the compound or salt, which is excellent in cell adhesion-inhibitory effect and cell infiltration-inhibitory effect: (1) (100) wherein R10 represe...  
WO/2006/129036
The invention concerns novel 1,2-dioxetane derivatives of general formula (I) as defined in the description, capable of emitting a detectable luminescent signal, their use in a method for detecting and/or quantizing a physical, chemical ...  
WO/2006/129736
It is intended to provide an industrially advantageous process for producing a cyclic ester, an industrially advantageous process for producing a cyclic oxyester which is a raw material of poly(hydroxyalkyloxyacetic acid ester), and an i...  
WO/2006/129036
The invention concerns novel 1,2-dioxetane derivatives of general formula (I) as defined in the description, capable of emitting a detectable luminescent signal, their use in a method for detecting and/or quantizing a physical, chemical ...  

Matches 301 - 350 out of 3,567