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Matches 301 - 350 out of 6,760

Document Document Title
WO/2008/089462A3
The present invention relates to compounds containing 1,3-dioxane moiety, pharmaceutical compositions thereof, and the use of the compounds and compositions for the modulation of thromboxane A2 or a peroxisome proliferator-activated rece...  
WO/2008/088487A2
Phosphorus-sulfur compounds have flame retardant activity in organic polymer systems. The phosphorus-sulfur compounds can be represented by the structure: Formula (I) wherein X is oxygen or sulfur, T is a covalent bond, oxygen, sulfur or...  
WO/2008/088487A3
Phosphorus-sulfur compounds have flame retardant activity in organic polymer systems. The phosphorus-sulfur compounds can be represented by the structure: Formula (I) wherein X is oxygen or sulfur, T is a covalent bond, oxygen, sulfur or...  
WO/2008/080822A1
The present invention relates to methods of subjecting a mixture of stereoisomers to epimerization and optionally recrystallization procedures to obtain a desired stereoisomer in high yield and purity. Relying upon solubility differences...  
WO/2008/080823A1
The present invention relates to methods of reducing ketal acids, salts and esters to form corresponding ketal alcohols. More particularly, the reducing methods convert the ketal acids, salts, or esters to ketal alcohols by using a reduc...  
WO/2008/080824A1
The present invention advantageously provides ketal functional compounds that can be strong electrophiles under conditions compatible with ketal groups, are stable, crystalline solids at room temperature, and are much safer to handle tha...  
WO/2008/078762A1
Disclosed are: a study on the synthesis of a novel N-(2-aminophenyl)benzamide derivative having an urea structure and represented by the general formula (1); and the utilization of the pharmacological activity of the derivative. A compou...  
WO/2008/075165A1
An improved synthesis for the preparation of [R-(R*, R*)]-2-(4-fluorophenyl)- β, δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1 H-pyrrole-1-heptanoic acid or a pharmaceutically acceptable salt thereof, as well as o...  
WO/2008/075353A1
The present invention relates to sulfonamide derivatives of formula (I) (wherein R1, R2, R3, R3', R4and R5are as defined in the claims), to pharmaceutical compositions comprising the same, and to uses thereof. Compounds of the invention ...  
WO/2008/071776A3
The raw material used in m ost process for the production of cyclic diesters of alpha - hydroxiacids, such as Lactide and Glycolide, is a 10% solution of Hydroxyacid. During the evacuation of the solution and condensation reaction water,...  
WO/2008/071776A2
The raw material used in m ost process for the production of cyclic diesters of alpha - hydroxiacids, such as Lactide and Glycolide, is a 10% solution of Hydroxyacid. During the evacuation of the solution and condensation reaction water,...  
WO/2008/067911A1
The invention relates to new compounds of the formula (I) in which W, X, Y, Z and CKE have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, an...  
WO/2008/061871A1
The present invention relates to ketomethionine ketals or hemiketals and their derivatives and also their preparation and their use as fodder additives, in particular for the nutrition of ruminants.  
WO/2008/061821A1
The present invention relates to a process for preparing tetramethyl glycolide, in which a composition comprising at least 50% by weight of 2-hydroxyisobutyric acid and/or tetramethyl glycolide is heated to a temperature of at least 100°C.  
WO/2008/058402A1
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy,...  
WO/2008/052086A1
Compounds are described herein which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds have the formula I: or pharmaceutically acceptable salts thereof, wherein each of A, R1, R2, R3, R4, Ra, ...  
WO/2008/047651A1
Disclosed is a process for producing flake-like dried DOG. In the process, DOG having a liquid content of 10 to 50 mass% is subjected to a continuous melting/drying step under specific conditions. The resulting product is subjected to a ...  
WO/2008/043947A1
The invention relates to a method for the synthesis of cyclic acetals that comprises reacting at least one carbonyl-function compound selected from aldehydes, ketones and/or linear acetals, on a polyol in a concentrated aqueous solution ...  
WO/2008/031157A1
The present invention relates to a class of acetylenic compounds, to a method of preparing the acetylenic compounds, and to the polymerisation and therapeutic uses of the acetylenic compounds. The invention particularly relates to compou...  
WO/2008/016199A1
The present invention relates to a process for the preparation of chiral 2-hydroxymethyl-l,4-benzodioxane compound. The method in accordance with the present invention comprises the steps of reacting chiral epihalohydrin or chiral glycid...  
WO/2008/015885A1
Disclosed is a method for purifying a hydroxycarboxylic acid by distillation, which is characterized by distilling an aqueous hydroxycarboxylic acid solution containing a high boiling point hydroxy compound which is composed of at least ...  
WO/2008/011742A1
A method of using organic compounds and providing slow release flavoring in or for food products wherein flavor precursors are added to flavor compositions and/or food products and release flavor compounds upon consumption of the food pr...  
WO/2008/012950A1
Disclosed are: a composition useful for the detoxification of a toxic compound containing arsenic or the like efficiently and systematically; and a method for the detoxification of a toxic compound using the composition. Specifically, di...  
WO/2008/013550A1
Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more fluorine atoms into target substrate compounds.  
WO/2008/010455A1
Disclosed is a method for producing a β-diaryl electron-withdrawing group substituted compound at high yield with high selectivity. Specifically, an optically active β-diaryl electron-withdrawing group substituted compound represented ...  
WO/2008/007780A1
Disclosed is a pentadienamide derivative represented by the formula (I) or a pharmaceutically acceptable salt thereof or the like. (I) wherein R1 represents a substituted or unsubstituted aryl or a substituted or unsubstituted aromatic h...  
WO/2008/006860A2
This invention describes the preparation of fatty acid esters of glycerol formal either by a triglyceride transesterification process or, alternatively, by an esterification process of fatty acids previously obtained from the hydrolysis ...  
WO/2007/148975A3
The invention relates to a method for the purification or recovery of lactide rich streams by the combination of a suspension-based melt crystallization process with a subsequent separation of the pure lactide crystals in a wash column.  
WO/2007/148975A2
The invention relates to a method for the purification or recovery of lactide rich streams by the combination of a suspension-based melt crystallization process with a subsequent separation of the pure lactide crystals in a wash column.  
WO/2007/139062A1
[PROBLEMS] To provide a prophylactic and therapeutic agent for obesity which has a more effective and potent efficacy and has reduced adverse side-effects, and also provide a method for prevention and treatment of obesity. [MEANS FOR SOL...  
WO/2007/138485A2
1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections.  
WO/2007/138485A3
1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections.  
WO/2007/139998A2
The present invention provides methods for preparing a compound of formula D having activity as dopamine autoreceptor agonist and partial agonists at the postsynaptic dopamine D2 receptor. This compound is useful for treating dopaminergi...  
WO/2007/139998A3
The present invention provides methods for preparing a compound of formula D having activity as dopamine autoreceptor agonist and partial agonists at the postsynaptic dopamine D2 receptor. This compound is useful for treating dopaminergi...  
WO/2007/136790A2
Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.  
WO/2007/136790A3
Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.  
WO/2007/133751A2
A stabilized semi-solid delivery vehicle contains a polyorthoester and an excipient, and a pharmaceutical composition contains an active agent, optionally a stabilizing agent, and the delivery vehicle. The pharmaceutical composition may ...  
WO/2007/133751A3
A stabilized semi-solid delivery vehicle contains a polyorthoester and an excipient, and a pharmaceutical composition contains an active agent, optionally a stabilizing agent, and the delivery vehicle. The pharmaceutical composition may ...  
WO/2007/127309A2
Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.  
WO/2007/127309A3
Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.  
WO/2007/123942A3
The present invention relates to methods for synthesizing compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein each of R1, R2, R3, R4, x, m, n, and Ar are as defined, and described in classes and sub...  
WO/2007/123942A2
The present invention relates to methods for synthesizing compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein each of R1, R2, R3, R4, x, m, n, and Ar are as defined, and described in classes and sub...  
WO/2007/115968A3
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclope ntyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secr...  
WO/2007/115968A2
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclope ntyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secr...  
WO/2007/114213A1
[PROBLEMS] To provide a compound capable of inhibiting the production of a prostaglandin or leukotriene. [MEANS FOR SOLVING PROBLEMS] Disclosed is a compound represented by the general formula (I) or a salt thereof: (I) wherein (a) repre...  
WO/2007/107276A2
The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly...  
WO/2007/107276A3
The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly...  
WO/2007/099553A3
The present invention relates to novel 1,3-dioxane carboxylic acids of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods fo...  
WO/2007/099553A2
The present invention relates to novel 1,3-dioxane carboxylic acids of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods fo...  
WO/2007/096261A3
The present invention is concerned with a novel process for the preparation of compounds of formula (I), wherein R1 and R2 are as defined in the description and claims. The compounds of formula (I) are pharmaceutically active substances.  

Matches 301 - 350 out of 6,760