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WO/2015/049535A1 |
The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to t...
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WO/2015/049940A1 |
The present invention relates to a compound having a 2,6-difluorophenyl ether structure, which is useful as an organic electronic material or a medicinal or agrochemical agent, particularly a material for liquid crystal display elements....
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WO/2015/048692A1 |
The invention relates to aryl substituted aminomethyl spectinomycin analogs, derivatives thereof, and related compounds, which are useful as anti-bacterial agents; methods for making the compounds; pharmaceutical compositions comprising ...
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WO/2015/042397A1 |
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associat...
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WO/2015/032622A1 |
An improved process for preparing Carfilzomib of Formula 13 is provided, as well as novel compounds that can be used as intermediates in the process for preparing Carfilzomib.
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WO/2015/034820A1 |
Disclosed are compounds of Formula (I): (I). Also disclosed are methods of using such compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowin...
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WO/2015/030189A1 |
Provided is a compound which exhibits bone formation acceleration activity (and/or bone resorption suppression activity). The compound is either a compound having a general formula (I) (wherein the substituents are as defined in the desc...
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WO/2015/016815A1 |
Antiperspirant and/or deodorant compositions containing lactic acid oligomers. The lactic acid oligomers provide a long lasting protection.
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WO/2015/012156A1 |
The present invention pertains to compounds having a 2,6-difluorophenyl ether structure useful as an organic electronic material, or a medical or agricultural chemical, and particularly as a material for liquid crystal display elements; ...
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WO/2015/009061A1 |
The present invention relates to a polyketone polymerization catalyst and, more specifically, to: a novel polyketone polymerization catalyst, which is prepared by using ((2,2-dimethyl-1,3-dioxane-5,5-diyl)bis(methylene))bis(bis(2
-methox...
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WO/2014/202168A1 |
Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, card...
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WO/2014/203045A1 |
The present invention provides a process of preparation of an intermediate useful for the preparation of statins more particularly the present invention relates to an eco-friendly and cost effective process for the preparation of tert -b...
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WO/2014/200682A1 |
Both JNK and LRRK2 are associated with Parkinson's disease (PD), myocardial infarction (Ml), and other medical disorders. Here we report a reasonably selective and potent kinase inhibitors (e.g., compounds 6 and 10) that bound to both JN...
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WO/2014/192627A1 |
A liquid crystal medium that has stability to heat, light and the like, also has extremely high dielectric anisotropy, and can develop an optically isotropic liquid crystal phase has been demanded. Various optical elements each of which ...
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WO/2014/180556A1 |
The present invention relates to arylpiperazines, and to the efficient treatment of an individual afflicted with L-DOPA-induced dyskinesia, which condition typically arises as a consequence of long-term treatment with L-DOPA therapy in P...
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WO/2014/180836A1 |
The invention relates to a process for the recovery and production of meso-lactide from a crude lactide containing stream, which comprises the steps of: a. Subjecting a starting crude lactide stream to a first distillation step to obtain...
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WO/2014/177512A1 |
The invention relates to a method for storage and/or transport of solid lactide particles in a container, said method comprising the steps of a) inserting the lactide particles into the container, b) storing and/or transporting the lacti...
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WO/2014/173047A1 |
A technological method for synthesizing optical pure L-/D-lactide by using a biomass organic guanidine catalysis method. The method of the present invention comprises: by using biomass organic guanidine compound creatinine (CR) as a cata...
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WO/2014/176151A1 |
The present application relates to perfume delivery systems and consumer products comprising such perfume delivery systems, as well as processes for making and using such perfume delivery systems and consumer products. Such perfume deliv...
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WO/2014/171894A1 |
The present invention provides a method of synthesizing a cyclic carbonate comprising the step of reacting an alcohol with carbon dioxide.in the presence of a base.
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WO/2014/157140A1 |
A method for producing glycolide (GL) by heating a glycolic acid oligomer (GAO) to depolymerize the GAO. The method comprises: a step (1) of heating a mixture comprising GAO having a terminal COOH concentration of 400 eq/t or less and a ...
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WO/2014/156809A1 |
In the present invention, a method for producing a glycolide (GL) includes the following: (I) a heating step of heating a mixture either under atmospheric pressure or reduced pressure at a temperature whereby a poly(glycolic acid) (PGA) ...
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WO/2014/150782A1 |
A ketal amide has a structure represented by formula (I): wherein R is hydrogen or C1-8 alkyl; R1 is substituted or unsubstituted, saturated or unsaturated C1-36 alkyl, or an alkylene oxide of the formula (CnH2nO)pCnH2nORa wherein n is 1...
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WO/2014/140220A1 |
The present invention is directed to aprocess for the preparation of (2,3- dihydrobenzo[b][1,4]dioxin-2-yl)methanolderivatives.
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WO/2014/139730A1 |
The invention relates to a process for purification of a stream containing a cyclic ester of an alpha- hydroxycarboxylic acid of formula (I), wherein each R independently represents hydrogen or an aliphatic hydrocarbon having 1 to 6 carb...
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WO/2014/129268A1 |
Provided are: a liquid crystal compound satisfying at least one property such as high stability to light, high clearing point, low minimum temperature of the liquid crystal phase, low viscosity, suitable optical anisotropy, large dielect...
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WO/2014/125911A1 |
Provided are: a liquid-crystalline compound which satisfies at least one property selected from high stability to light, a high clear point, a low lower-limit temperature of a liquid crystal phase, a low viscosity, proper optical anisotr...
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WO/2014/122294A1 |
The invention relates to a process for preparing a cyclic ester or a cyclic amide, comprising the step of: contacting at least one hydroxycarboxylic acid and/or at least one amino-carboxylic acid; or an ester, or salt thereof; wherein sa...
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WO/2014/111490A1 |
The present invention relates to a new biofuel formulation comprising: crude glycerol, glycerol formal, optionally at least one fatty acid glycerol formal ester and optionally at least one fatty acid methyl ester. The present invention a...
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WO/2014/097171A1 |
The present invention relates to a process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated ketones, unsaturated ketals, unsaturated aldehydes, unsaturated acetals, unsatur...
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WO/2014/096066A1 |
The present invention relates to a process of manufacturing (6R,10R)-6,10,14-trimetylpentadecan-2-one in a multistep synthesis from (R)-3,7-dimethyloct-6-enal. The process is very advantageous in that it forms in an efficient way the des...
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WO/2014/097952A1 |
Provided is a chiral compound having considerable helical twisting power, a low melting point, and good solubility with other liquid-crystal compounds. Also provided is a liquid-crystal compound composed of the chiral compound of the pre...
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WO/2014/096063A1 |
The present invention relates to a process of manufacturing (6R,10R)-6,10,14-trimetylpentadecan-2-one in a multistep synthesis from 3,7-dimetyloct-2-enal or 3,7-dimetylocta-2,6-dienal. The process is very advantageous in that it forms th...
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WO/2014/097172A1 |
The present invention relates to a process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated ketones, unsaturated ketals, unsaturated aldehydes, unsaturated acetals, unsatur...
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WO/2014/083936A1 |
The present invention addresses the problem of providing a method that produces a higher yield of a carbonyl compound. In this production method for a carbonyl compound, dealkoxycarbonylation of a compound represented by formula (II) is ...
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WO/2014/083935A1 |
The present invention addresses the problem of providing a method that produces a higher yield of a carbonyl compound. In this production method for a carbonyl compound, dealkoxycarbonylation of a compound represented by formula (II) is ...
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WO/2014/083186A2 |
There is provided a compound comprising the general structure (I) in which, X is N or O; R3 is OR4 or R4; wherein when X is N, R1 is H, R5 or OR6; R2 is OC(O)R7; and R4 is R5, OR5 or aryl, which is unsubstituted or substituted with at le...
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WO/2014/083911A1 |
A method for producing a cyclopentanone derivative represented by general formula (III), wherein a cyclopentanone derivative represented by general formula (III) can be produced with higher yield since the method comprises a step wherein...
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WO/2014/081558A1 |
Disclosed is a process for making diastereomeric N-sulfinyl α-amino amides by reaction of chiral sulfinimines with formamides and lithium diisopropylamide. The process of the invention provides the N-sulfinyl α-amino amides in high yie...
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WO/2014/080876A1 |
A method for producing GL, which is provided with: step (1) wherein a GAO composition, which preferably contains a high-boiling-point organic solvent or a solubilizing agent, is supplied into a reaction container and heated to a temperat...
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WO/2014/074365A1 |
The present invention provides compounds of Formula I. Wherein Rl, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridem...
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WO/2014/072453A1 |
The present invention relates to a process for obtaining simultaneously several compositions comprising fatty acid alkyl esters (biodiesel), glycerol formal and fatty acid glycerol formal esters.
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WO/2014/064160A1 |
The present invention relates to a process for preparing cyclic carboxylic esters, especially intramolecular lactones, for example dilactide, wherein these cyclic esters are prepared from oligomeric carboxylic acids by cyclizing depolyme...
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WO/2014/065293A1 |
A liquid-crystal composition exhibiting an optically isotropic liquid crystal phase, and containing a chiral agent and an achiral component (T) which contains one or more types of a compound (1) having: a dioxane ring which is unsubstitu...
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WO/2014/054391A1 |
A compound represented by general formula (1). In general formula (1), R1 represents either one of a protective group for a hydroxy group and a hydrogen atom, and R2 and R3 independently represent a protective group for an amino group.
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WO/2014/053694A1 |
Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.
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WO/2014/046193A1 |
Provided are: an organocopper complex having a structure represented by general formula (1); a copper oxide thin film comprising the organocopper complex; a method for producing the copper oxide thin film; and a compound constituting the...
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WO/2014/041059A1 |
The invention provides a process for the production of a compound of formula (I), said process comprising reacting a compound of formula (II) with a compound of formula (III) wherein R1 and R2 may be the same or different and are selecte...
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WO/2014/041058A1 |
The invention provides a process for the production of 1 a compound of formula (I), said process comprising reacting a compound of formula (II), with a compound of formula (III), wherein R1 and R2 may be the same or different and are sel...
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WO/2014/036766A1 |
Provided is a smectic phase A liquid crystal material, comprising a heterocyclic compound; the heterocycle is a nitrogen-containing heterocycle formed by replacing 1-4 carbon atoms in a benzene ring with nitrogen atoms, or a heterocycle ...
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