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WO/2020/251745A1 |
Polylactide resin compositions that exhibit rapid hydrolysis rates and leave small amounts of residuals include a poly(meso-lactide) and a second polylactide. The polylactide resin compositions are useful in applications in which rapid h...
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WO/2020/244518A1 |
The present invention provides a compound with benzyloxy aromatic ring structure represented by general formula (I), a stereoisomer, enantiomer or pharmaceutically acceptable salt thereof, a preparation method thereof, a pharmaceutical c...
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WO/2020/239980A1 |
The present invention relates to an arthropod controlling composition comprising a compound according to formula (I), methods and uses to control arthropods as well as arthropod controlling articles comprising the same.
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WO/2020/230822A1 |
The present disclosure provides a method with which a fluorolactone compound can be produced in a single step from hexafluoropropylene oxide or the like. The present disclosure relates to a method for producing a compound represented by ...
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WO/2020/224396A1 |
Provided in the present invention are a class of compounds inhibiting TDG activity. In particular, provided in the present invention is a compound as shown in formula I and which has a new structure. The small-molecule inhibitor of the p...
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WO/2020/223536A1 |
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.
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WO/2020/209035A1 |
A compound represented by formula (1). R1 is, for example, an alkyl having 1-15 carbon atoms; ring A1 and ring A2 are 1,4-phenylene, etc.; a is 2, etc.; b and c are 0, 1, or 2; Z1 is a single bond, etc.; P1 and P2 are polymerizable group...
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WO/2020/193650A1 |
The invention relates to a new process for preparing a 1,2-endoperoxide compound of formula (I) as well as to products obtained by said process.
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WO/2020/184142A1 |
[Problem] To provide a compound which has high stability with respect to heat, high voltage holding ratio if used in a liquid crystal display element, and the like. [Solution] A compound which is represented by formula (1). In the formul...
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WO/2020/178053A1 |
Phenol derivatives of general formula (I) and (II), wherein meanings of the substituents are indicated in the description, their pharmaceutically acceptable salts, together with the processes for their preparation, their use as antimicro...
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WO/2020/173016A1 |
The present invention relates to a resorcinol dianisole derivative, wherein the chemical structure of this compound is as represented by the following formula (I). The compound of the present invention can inhibit the binding of programm...
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WO/2020/169770A1 |
The invention discloses a method for the preparation of fluoro alkylated 1,4-dioxene by homogene- ous Ni catalyzed fluoro alkylation with fluoro alkyl halides of 1,4-dioxane in the presence of a base.
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WO/2020/169768A1 |
The invention discloses a method for the preparation of fluoro alkylated compounds by homogeneous Ni catalyzed fluoro alkylation with fluoro alkyl halides in the presence of a base.
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WO/2020/166632A1 |
The present disclosure provides: a method which is capable of producing a fluorolactone compound from hexafluoropropylene oxide or the like by a single step; and the like. The present disclosure relates to a method for producing a comp...
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WO/2020/148619A1 |
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...
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WO/2020/127924A1 |
The invention relates to a process for the preparation of Voxelotor, or a salt or solvate thereof, which comprises the use of a compound of formula (I) or (I'), or a salt or solvate thereof.
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WO/2020/124433A1 |
Provided herein is a process for preparing acetals or ketals by reacting Alcohol I, Alcohol II and oxygen in the presence of a metal-organic framework (MOF) catalyst.
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WO/2020/114905A1 |
According to the present invention a process is provided for producing glycolide which comprises contacting glycolaldehyde dimer with an oxidizing agent to produce a glycolide product.Preferably, the process is carried out in an aprotic ...
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WO/2020/106028A1 |
The present specification provides a compound represented by chemical formula 1 and an organic light-emitting device comprising same.
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WO/2020/087217A1 |
The invention relates to a process of preparing a glycolide product from methyl polyglycolate or its product. The process comprises depolymerizing the methyl polyglycolate or its product in the presence of a depolymerization agent to mak...
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WO/2020/087221A1 |
Provided is a process for producing a product having polyglycolic acid and glycolide from methyl glycolate. The process comprises esterification, polycondensation and optimization. Also provided are a product produced by the process and ...
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WO/2020/087223A1 |
The invention relates a novel polyglycolic acid. The polyglycolic acid comprises branched repeating units and linear repeating units. The polyglycolic acid may be produced from methyl glycolate by polycondensation in the presence of stru...
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WO/2020/092383A1 |
The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processe...
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WO/2020/086864A1 |
Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders...
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WO/2020/081836A1 |
The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.
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WO/2020/064701A1 |
The present invention generally relates to the formation, chemistry and application of biologically active compositions. More particularly, the present invention relates to certain dyes, specifically porphyrin and chlorin derivatives, in...
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WO/2020/064818A1 |
Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.
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WO/2020/041927A2 |
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WO/2020/020365A1 |
The present invention involves a method for isolating, by means of salt formation and resolution, a single optically active N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxan-6-yl)-2-hydroxy-1-
(1-pyrrolidinylmethyl)ethyl]octanamide as shown in f...
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WO/2020/009132A1 |
The present invention pertains to a novel method for producing diarylpyridine derivatives, the purpose of the present invention being to provide a industrially useful, novel method. A novel method for synthesizing pyridine rings without ...
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WO/2019/242687A1 |
The present invention discloses a 1,3-dioxane-4,6-dione compound, and a preparation method, a pharmaceutical composition, and an application thereof. The structure of the compound is represented by formula I, and the definition of each s...
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WO/2019/233474A1 |
The present disclosure relates to compounds with antiviral activity, methods for the preparation ofsuch compounds, and their use to inhibit viral nucleoprotein activity, viral transcription, replication, and assembly into the newly forme...
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WO/2019/228994A1 |
This invention relates to oleic acid derivative comprising a hydrophobic part C17H33 linked to a particular polar head part "A", especially for use as a medicament, for instance, for the treatment of a disorder caused by the GPR120 recep...
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WO/2019/219210A1 |
The present invention relates to a process for producing an intramolecular diester of a hydroxycarboxylic acid, wherein in a first step a hydroxycarboxylic acid is polycondensed to form an oligomeric hydroxycarboxylic acid. This is follo...
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WO/2019/185877A1 |
The invention relates to a method for the preparation of a 4,5-dihydroxyisoleucine derivative comprising the steps of asymmetric Claisen rearrangement of a Z-aminocrotyl-glycin ester and subsequent kinetic resolution of the product diast...
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WO/2019/191445A1 |
A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a...
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WO/2019/191189A1 |
The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disor...
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WO/2019/181298A1 |
This invention addresses the problem of providing a method for producing glycolides, with which glycolides can be produced more rapidly. This method for producing glycolides that solves the problem comprises: an oligomer preparation step...
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WO/2019/181340A1 |
The purpose of the present invention is to provide a glycolide production method capable of further increasing the rate of production of glycolide. The glycolide production method according to the present invention comprises a step for a...
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WO/2019/181516A1 |
The purpose of the present invention is to provide a glycolide production method capable of sufficiently increasing the rate of production of glycolide. The glycolide production method according to the present invention comprises a step ...
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WO/2019/173772A1 |
The present disclosure is directed to l-(2-hydroxy-4-methylcyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of ...
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WO/2019/172361A1 |
According to this method for producing a cyclic ester, a mixture (I) that contains an aliphatic polyester, a specific polyalkylene glycol diether, and a sulfonic acid compound which serves as a thermal stabilizer is prepared and is subse...
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WO/2019/165687A1 |
A photo-alignment material, a liquid crystal display panel and a preparation method therefor. A chemical structural formula of the photo-alignment material comprises a first group, a second group, a third group, and a fourth group which ...
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WO/2019/151384A1 |
One embodiment of the present invention relates to novel substances, etc., which are: [1] a compound, etc., represented by formula (A1) or formula (B1); [2] a compound, etc., represented by formula (A2) or formula (B2); [3] a compound, e...
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WO/2019/145719A1 |
The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula (I), and to compounds of For...
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WO/2019/145718A1 |
The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula(I), and to compounds of Form...
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WO/2019/128918A1 |
Disclosed in the present invention are an aromatic vinyl or aromatic ethyl derivative, a preparation method therefor, an intermediate, a pharmaceutical composition, and an application. The aromatic vinyl or aromatic ethyl derivative in t...
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WO/2019/120101A1 |
Disclosed is a compound having the structure of formula I. Also disclosed is a liquid crystal composition comprising the compound of formula I, and a photoelectric display component comprising the liquid crystal composition. The compound...
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WO/2019/124092A1 |
The present invention provides: a compound represented by formula (i), a liquid crystal composition using said compound, and a liquid crystal display device using said liquid crystal composition. The compound represented by formula (i) h...
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WO/2019/123476A1 |
The present invention relates to pharmaceutical compositions of Eliglustat. In particular the present invention relates to stable amorphous Eliglustat premix having enhanced stability and dissolution properties. The present invention als...
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