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Matches 201 - 250 out of 3,143

Document Document Title
WO/2015/175984A1
Described herein are compounds which can be used in topical liquids, creams, or other dosage forms such as solids, for reducing intraocular pressure, treating glaucoma, growing hair, treating wounds, or other medical and/or cosmetic uses.  
WO/2015/169854A1
The invention provides a method for the preparation of regioisomerically pure intermediates which are useful for the preparation of carboxy-fluorescein-type compounds. Such compounds have broad applications within bio-conjugation and/or ...  
WO/2015/159098A1
There are provided compounds of the formula D-S1-A-S2-B1 wherein A comprises a 2,7- disubstituted 9,9-fluoroalkyl fluorene diradical of the formula wherein S1, S2, D and B1 have meanings given in the description that are useful as charge...  
WO/2015/157082A1
Disclose are methods for minimizing the recycle of para-toluic acid within a terephthalic acid purification plant. Specifically, the disclosed methods remove a portion of the p-toluic acid from the pure plant flash condensate and recycle...  
WO/2015/157239A1
The disclosure provides for metal organic frameworks (MOFs) which comprise a plurality of SBUs linked together by functionalized or multivariate BTB-based linking ligands. The disclosure further provides for the use of these MOFs in vari...  
WO/2015/157187A1
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the c...  
WO/2015/137272A1
The present invention provides a porous structure containing at least two kinds of metal ions and an organic ligand, said porous structure being characterized in that the at least two kinds of metal ions are homogeneously mixed together ...  
WO/2015/124651A1
The present invention relates to a process for providing a compound of formula (IV):wherein R1 and R2 are each independently C1-C4 alkyl, and Hal is independently Cl or Br, the process comprising the steps of: (i) reacting a compound of ...  
WO/2015/120115A1
Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.  
WO/2015/110502A1
A composition comprising a polymer, or an oligomer, comprising cross-linking moiety, which moiety comprises a carbon-carbon triple bond; and a molecule comprising a carbon-carbon triple bond, wherein the thermal curing behavior of said m...  
WO/2015/092720A1
Provided herein are metabolites of N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)- 2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide (Sonidegib, LDE225) that modulate the activity of the Hedgehog signaling pathway and tha...  
WO/2015/086698A1
The present invention relates to a process for providing dihalogen substituted salicylic acid derivativesof formula (II).  
WO/2015/078920A1
The present invention relates to a process for depolymerization of lignin, comprising a step of oxidation of non-phenolic lignin by bringing together, in at least one solvent, non-phenolic lignin, laccase, a redox mediator and an oxygen ...  
WO/2015/067494A1
The present invention relates to a process for providing: a compound of formula (IV): wherein R1 is hydrogen or -(C1-C4)alkyl, R2 is -(C1-C4)alkyl, and each Hal is an independently selected halogen, the process comprising the step of: Re...  
WO/2015/066693A1
The disclosure provides for Metal-Organic Frameworks comprising M2 (m-dobdc) -based cores, and methods of use thereof, including gas separation, gas storage, sensing, and other applications utilizing a high density of exposed metal catio...  
WO/2015/055116A1
An in-depth study is performed on selaginella pulvinata extractives in the present invention, and it is found that the selaginella pulvinata extractives have a significant anti-inflammatory activity. Multiple column chromatography separa...  
WO/2015/027669A2
Disclosed are a phenyl-substituted compound with structures represented by formula (1) and formula (2), a pharmaceutical composition and uses thereof. The compound can remarkably show in vivo and in vitro that the compound can kill and/o...  
WO/2015/010666A2
A phenol derivative and a use thereof are disclosed. The phenol derivative comprises a compound as represented by structural formulas (I), (II) or (III) or a pharmaceutically acceptable salt, ester and amide thereof. In structural formul...  
WO/2015/007181A1
Disclosed are 5-bromine-2-(α-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and a preparation method thereof, relating to the field of medicinal chemistry. The 5-bromine-2-(α-hydroxypentyl)benzoic acid sodium salts...  
WO/2015/002151A1
Provided is a method for stabilizing DHNA or a vitamin contained in a food, a beverage and or like under an environment which can be subjected to natural light or artificial light, e.g., a transparent container, without requiring the use...  
WO/2014/208632A1
The present invention addresses the problem of providing: a base generator which has high solubility in widely used organic solvents, can be dissolved directly in a base-reactive compound such as an epoxy compound, has both high heat res...  
WO/2014/205392A1
Disclosed herein are cocrystals of dimethyl fumarate and gentisic acid or (+)-camphoric acid. Dimethyl fumarate is a prodrug of methyl hydrogen fumarate. The cocrystals have improved physicochemical properties and are used in treating mu...  
WO/2014/197195A2
The present disclosure is related to silica-based Lewis acid catalysts, being essentially devoid of strong Bronsted acid character, and their ability to effect the [4+2] cycloaddition and dehydrative aromatization of dienes and dienophil...  
WO/2014/179263A1
The invention provides well-defined compounds, including compounds of the following formula, that are either EP2 agonists, EP4 agonists, or mixed EP2/EP4 agonist. The compounds are useful for treating a variety of pathological conditions...  
WO/2014/177593A1
The present invention relates to Amorfrutin analogues and stereoisomeric forms, solvates, hydrates, conjugates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of ...  
WO/2014/167017A1
The invention relates to a method for producing ortho-acylated aromatic or heteroaromatic carboxylic acids. According to the method, an aromatic or hetero-aromatic carboxylic acid or anhydride thereof, each of which has a CH group at the...  
WO/2014/164636A1
Cosmetic compositions comprising salicylic acid dimers and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against one or...  
WO/2014/164608A1
Cosmetic compositions comprising salicylic acid derivatives and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against o...  
WO/2014/164630A1
Cosmetic compositions comprising salicylic acid derivatives and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against o...  
WO/2014/123091A1
The object of the invention is to provide a method for producing a polymer having high solvent resistance and to provide a vinyl ester copolymer having high solvent resistance. Provided as a means for attaining the above object are: a me...  
WO/2014/115915A1
The present invention relates to a novel reactive mesogen compound, and a preparation method therefor, and more specifically, to: a novel reactive mesogen compound which has an intrinsic liquid crystal characteristic of having a molecula...  
WO/2014/095036A1
The invention relates to new compounds having fluorinated terminal groups of formula (I), use thereof as surface-active substances and agents containing said compounds, wherein X = a hydrophilic group, Y = linear or branched alkylene, wh...  
WO/2014/097772A1
Provided is a method for obtaining an ionic metal complex salt that uses an organic compound as a ligand in which silicon tetrachloride is used as a reaction aid when reacting a metal complex salt containing a fluorine atom with an organ...  
WO/2014/086723A1
The invention relates to the use of substituted 1 -(aryl ethynyl)-, 1 - (heteroaryl ethynyl)-, 1 -(heterocyclyl ethynyl)- and 1 -(cyloalkenyl ethynyl)- bicycloalkanols or salts thereof (I). The groups in general formula (I) correspond to...  
WO/2014/078173A1
A compound of formula (I) wherein Rf is -CF3, -C2F5, or -CF2CFXCF3; X is -F, or -OC3F7; Y is -H, -Cl, or -Br; R is -OH, -(CH2)nOH, -(OCH2CH2)mOH, -(CH2)n(OCH2CH2)mOH, -O-C(O)-R1, -(CH2)nO-C(O)-R1, -(OCH2CH2)mOC(O)-R1, -C(O)NHw(CH2CH2OH)2...  
WO/2014/069555A1
Provided is a compound that exhibits an excellent melanogenesis-inhibiting effect (skin-lightening effect), exhibits an excellent antimicrobial effect, excels in terms of temporal stability and the like, and is suitable for use as an ing...  
WO/2014/016145A1
The invention relates to a method for producing at least one alkoxy-hydroxybenzaldehyde (AHBA) from at least one hydroxyphenol (HP), said method being characterised in that it comprises the formation of at least one alkoxyphenol (AP) and...  
WO/2013/174916A1
Compounds particularly for use in an autoimmune inflammatory disease and especially the treatment of inflammatory bowel disease have the absolute stereochemistry and formula (I). In some cases R1 is leucine and R is selected from: OH, OC...  
WO/2013/140506A1
Provided is a method for manufacturing 4,4'-oxydiphthalic acid with favorable productivity and high-yield via 4,4'-oxydiphthalonitrile, using 4-nitrophthalonitrile as a reaction raw material; the method including a hydrolysis step for hy...  
WO/2013/129121A1
The problem to be solved by the present invention is to provide a liquid crystal composition which exhibits little haziness when subjected to liquid crystal alignment and made into a film, and with which cissing can be inhibited when a f...  
WO/2013/101322A1
A process for oxidizing an alkyl-aromatic compound to reduce the level of impurities is described. The solvent pH level controlled to reduce the impurities.  
WO/2013/101324A1
A process for oxidizing an alkyl-aromatic compound is described. The process includes oxidizing the alkyl-aromatic compound to produce a first oxidation product; contacting at least a portion of the first oxidation product, a solvent com...  
WO/2013/101335A1
A process for oxidizing an alkyl-aromatic compound is described. The process includes contacting the alkyl-aromatic compound, a solvent comprising a precursor of at least one ionic liquid, a bromine source, a catalyst, and an oxidizing a...  
WO/2013/091282A1
Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided...  
WO/2013/073815A1
The present invention relates to the synthesis of 2,2'-dihydroxy-1,1'-binaphthyl-3-carboxylic acid or a derivative thereof by reacting 2-hydroxynaphthalene or a derivative thereof and 3-hydroxy-2-naphthalene carboxylic acid or a derivati...  
WO/2013/021944A9
The present invention provides a complex in which metal nanoparticles are included in a porous coordination polymer (PCP), wherein the PCP is configured from a metal ion and an organic ligand.  
WO/2013/014660A1
Compounds particularly for use in an autoimmune inflammatory disease and especially the treatment of inflammatory bowel disease have the formula: wherein R is selected from one or more of the same or different of hydrogen, hydroxyl, opti...  
WO/2013/014659A1
Described are compounds of the structural formula (I): Also provided are pharmacologically acceptable isomers and salts of the compound of (I). The compounds are useful in the treatment of inflammatory bowel disease.  
WO/2013/000669A1
Fragrances having a fresh scent are usually very volatile and therefore not very economical in typical applications, such as washing or cleaning processes. Thus, said fragrances must be used in relatively large quantities, in order to br...  
WO/2012/167530A1
The present invention relates to a cleaning agent for a lubricating oil and the production process thereof, and a process method for producing an additive for a lubricating oil having a TBN of from about 100 to about 400, the process met...  

Matches 201 - 250 out of 3,143