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Matches 701 - 750 out of 4,842

Document Document Title
WO/2005/061524A2
The present invention provides an efficient process for the preparation of polymorphic Form I and II of clarithromycin. The process includes drying wet clarithromycin obtained after purification in the presence of nitrogen gas and in the...  
WO/2005/054265A2
Macrolides particularly erythromycins and azithromycins, having O-mycaminosyl or O-angolosaminyl groups, particularly at the 5-position, are produced using a gene cassette comprising a combination of genes which, in an appropriate strain...  
WO/2005/054267A1
The present invention relates to compounds of formula (1) and salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites thereof, wherein R1 is a glycosyl moiety, hydroxyl-protected acetate derivatives thereof or ami...  
WO/2005/053650A1
An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multipar...  
WO/2005/049598A1
The invention relates to novel hydrosoluble yellow colouring agents of general formula (I), wherein n is equal to 0 or 1, R1 is H or an alkyl group, R2 is H, a glucose group or a xyloglucose group. A method for preparing and using the in...  
WO/2005/049632A1
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of bifunctional compounds useful as therapeutic ag...  
WO/2005/049579A2
The present invention relates to immobilized N-substituted tricyclic 3-aminopyrazole compounds of Formula 1 as tools for the identification of bimolecular targets in cells of therapeutic significance, profiling the selectivity of compoun...  
WO/2005/044834A1
A method for preparing a stabilized azithromycin composition comprising mixing azithromycin monohydrate and water to form a stabilized azithromycin composition having a water content from about 5 to about 15 weight percent, based on the ...  
WO/2005/042554A1
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of bifunctional compounds useful as therapeutic ag...  
WO/2005/042555A1
A tyrosinase activity inhibitor and an ameliorant for facial blood flow which each is highly safe; and a medicinal composition, food composition, or cosmetic preparation each containing these as active ingredients. The tyrosinase activit...  
WO/2005/039500A2
The present invention provides methods for the isolation of a new group of actinomycetes and for the identification of members of this group based on characteristic nucleotide sequences and phylogenetic analyses. This group is phylogenet...  
WO/2005/034846A2
Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources....  
WO/2005/034856A2
The invention provides a prodrug platform technology for improving the therapeutic value of a variety of parent drug compounds by altering and improving drug characteristics such as aqueous solubility, hydrolytic stability, therapeutic i...  
WO/2005/036169A2
Fluorescent probes that have binding affinity to ribosome. The fluorescent probes are useful tools for identifying small molecules that bind to the 50S or 30S subunits of the bacterial and other ribosome inhibitors. These probes are also...  
WO/2005/033123A1
Disclosed is a compound represented by the following general formula (I): (I) (wherein R1 represent a glycosyl group, a phosphoric acid group , or a cyclic phosphoric acid group bonded with R2; R2 represents -CH2OH, -CHO, -CH2NH2, -CH2-a...  
WO/2005/030785A2
The invention relates to novel compounds of 5-thioxylose and, preferably, 5-thioxylopyranose-type derivatives. The invention also relates to the method of preparing said compounds and to the use of same as an active principle in medicame...  
WO/2005/030233A1
An active oxygen scavenging agent; and a process for producing the same. In particular, an active oxygen scavenging agent comprising as an active ingredient a product of decomposition of anthocyanin pigment derived from acerola; and a pr...  
WO/2005/030227A1
The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions com...  
WO/2005/028493A1
Antimicrobial compounds are provided having the formula (Q): as well as tautomers, stereoisomers, pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating b...  
WO/2005/028630A2
Disclosed herein are methods and compositions for modulation of gene expression, with single-gene specificity, in a human sized genome.  
WO/2005/027828A2
This invention features a compound of the following formula: T-(-L-C)m, T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or...  
WO/2005/027622A1
It is intended to provide a flower color crossing method whereby a specific flower color is passed to the next generation of delphinium and a flower color crossing method whereby a dichromatic flower color is passed to the next generatio...  
WO/2005/028492A1
The invention relates to a crystalline compound of 4'-demethyl-4'-phosphate-2',3'-bispentafluorophenoxyacetyl-4 ',6'-ethylidene-β-D-epipodophyllotoxin glucoside in its free form or solvated with ethanol, advantageously provided in the f...  
WO/2005/025490A2
A novel family of cyclic polyene natural products isolated from marine actinomycete strain CNQ 140 is provided. This novel strain of actinomycetes was obtained from a previously unstudied population of marine actinomycetes that reside in...  
WO/2005/021567A1
The present invention relates to a process for regioselective O-alkylation of macrolide and azalide derivatives, specifically 11-0-alkyl derivatives represented by formula (I) (1) R1 wherein A is 14-membered macrolide derivative and 15-m...  
WO/2005/021566A2
The invention relates to glucopyranosyloxy-pirazoles of formula (I), wherein R1 to R6 and R7a, R7b and R7c are defined in the claim 1, to the tautomers, stereoisomers, mixtures and the salts thereof, in particular the salts which are phy...  
WO/2005/018577A2
Compounds of formula (I) and R1, R 2 R 3 and R 4 are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility.  
WO/2005/018576A2
Compounds having the structure of formula I: wherein R1,R2,R3, R4, R5, and R6 are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility.  
WO/2005/019238A1
Compounds represented by the general formula (1) or pharmaceutically acceptable salts thereof, effective in the prevention and/or treatment of infections with microbes: (1) (a) wherein R1 is hydrogen or straight-chain C1-6 alkylcarbonyl;...  
WO/2005/016851A1
The invention relates to novel molecules and libraries thereof as well as methods for their production. Methods of producing the novel molecules include a. cleaving one or more of starting molecules into molecular subunits ; and b. assem...  
WO/2005/012322A1
A process for producing erythromycin A 11,12-cyclic carbonate (compound (II)) from erythromycin A (compound (I)), which is shown by the reaction scheme, [Chemical formula 1] (I) → (II) the process comprising reacting erythromycin A wit...  
WO/2005/012243A2
Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.  
WO/2005/012321A1
A compound of the formula (I): wherein Ring A and Ring B are (1) Ring A is an optionally substituted unsaturated monocyclic heterocyclic ring, and Ring B is an optionally substituted unsaturated monocyclic heterocyclic ring, an optionall...  
WO/2005/011592A2
Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.  
WO/2005/012242A2
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of d...  
WO/2005/012318A2
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.  
WO/2005/010019A1
Crystalline 6-N-pyridylmethylamino-12,13-dihydro-2,10 -dihydroxy-12-β-D-glucopyranosyl-5H-indolo[2,3-a]pyrrolo[3, 4-c]carbazole-5,7(6H)-diones in the form of the free bases as represented by the general formula (I), pharmaceutically acc...  
WO/2005/010018A1
6-N-Pyridylmethylamino-12,13-dihydro-2,10-dihydroxy- 12-β-D-glucopyranosyl-5H-indolo[2,3-a]pyrrolo[3,4-c]carba- zole-5,7(6H)-dione free bases (I) in the form of crystals; pharmaceutically acceptable salts of the same; or solvates thereo...  
WO/2005/010017A1
A compound represented by the formula [I] (wherein R represents unsubstituted pyridyl, furyl, or thienyl; m is an integer of 1 to 3; G represents ß-D-glucopyranosyl; and the hydroxy substituents on the indolopyrrolocarbazole ring are lo...  
WO/2005/010020A1
A compound represented by the formula [I] (wherein R represents unsubstituted pyridyl, furyl, or thienyl; m is an integer of 1 to 3; G represents β-D-glucopyranosyl; and the positions of the hydroxy substituents on the indolopyrrocarbaz...  
WO/2005/009398A2
The invention relates to Tetracyclic Benzamide Derivatives; compositions comprising a Tetracyclic Benzamide Derivative; and methods for treating or preventing an inflammatory disease, a reperfusion disease, an ischemic condition, renal f...  
WO/2005/007666A1
Disclosed is a method for producing a compound represented by the following formula (I): (I) (wherein R1 is a hydrogen atom or a lower acyl group, R2 represents a hydrogen atom, a lower acyl group or the like, R3 represents a lower alkyl...  
WO/2005/003112A1
A flavonoid solubilization agent capable of solubilizing to a high degree flavonoids such as isoflavon, baicalin, rutin and naringin whose solubility is generally low; and a method of effecting the above solubilization. Flavonoids can be...  
WO/2005/003146A1
The present invention relates to the C-glycosylisoflavones having alkylaminoalkoxyl substituent, the pharmaceutic salt thereof, and the preparation thereof, and to the pharmaceutical compositions comprising effective amount of general fo...  
WO/2005/003144A1
A direct, single step process for preparing a semi-synthetic antibiotic azithromycin dihydrate (non-hygroscopic) is provided, by in situ reductive N-methylation of azaerythromycin A and subsequent crystallization from a mixture of aceton...  
WO/2005/003145A1
Provided are compositions and formulations containing an SZY extract or its active ingredients, loganin, morroniside, and cornuside. Also disclosed is a method of treating pain, autoimmune diseases, and inflammation using such compositio...  
WO/2005/000860A2
Compositions and methods for treatment of disease with acetylated disaccharides and analogs thereof are provided.  
WO/2005/000319A1
It is intended to provide a skin composition for external use that contains an ascorbic acid derivative having a high stability, being continuously usable in vivo, having a strong antioxidant effect and showing little skin irritation and...  
WO/2005/000863A2
The present invention discloses compounds of formula (I), or pharmaceutically acceptables salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions co...  
WO/2004/110255A2
The present invention relates to novel antineoplastic agents and cancer diagnostic agents that specifically target neoplastic cells via the GLUT transportation system. More specifically, the invention relates to conjugates of 2­-deoxygl...  

Matches 701 - 750 out of 4,842