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Patent Searching and Data


Matches 701 - 750 out of 6,658

Document Document Title
WO2005002497A3
A novel group of aminoglycosides which share some structural features of currently available aminoglycosides with regard to the backbone, while also having significant structural differences. The similarity enables these aminoglycosides ...  
WO2006024405A3
A compound of the formula (I) wherein the bond between carbon atoms 22 and 23 indicated with a broken line is a single or double bond, n is 0, 1 or 2, R1 represents, for instance, a C1-C12alkyl group, R2 represents, for instance, R15 gro...  
WO/2006/050943A1
A compound of formula (I) For use as antibacterial agents, compositions containing same, processes for their preparation and their use in therapy.  
WO/2006/050941A1
A compound of formula (I) compositions comprising same, processes for their preparation and use of said compounds, particularly in the treatment of microbial infections.  
WO/2006/050940A1
A compound of formula (I) compositions comprising same, processes for their preparation and use of said compounds, particularly in the treatment of microbial infections.  
WO/2006/050942A1
Compounds of formula (I) or pharmaceutically acceptable derivatives thereof having antimicrobial activity are disclosed, as are processes for their preparation, compositions containing them and their use in medicine.  
WO/2006/049983A2
Modified fusion proteins of transferring and therapeutic proteins or peptides including, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exh...  
WO/2006/045831A1
The present invention describes natamycin comprising needle shaped crystals.  
WO/2006/047167A2
9-Alkyl- and 9-alkylidenyl-6-O-alkyl-11,12-carbamate-ketolide and 9-alkylidene-6-O-alkyl-11,12-carbamate-ketolide antimicrobials of the Formula: wherein Ra, Rb, Rc R, L, T, Y, and Z are as described herein and in which the substituents h...  
WO/2006/046112A2
The present invention provides ketolide derivatives, which can be used as anti-bacterial agents. Compounds disclosed herein can be used for the treating or preventing conditions caused by or contributed to by gram positive, gram negative...  
WO2005028492A8
The invention relates to a crystalline compound of 4'-demethyl-4'-phosphate-2",3"-bispentafluorophenoxyacetyl-4 ",6"-ethylidene-ß-D-epipodophyllotoxin glucoside in its free form or solvated with ethanol, advantageously provided in the f...  
WO/2006/042454A1
The present invention provides acetylated derivatives of the compound puerarin that have enhanced bioavailability and are particularly suitable for oral administration. The present invention also teaches the use of medicaments containing...  
WO2005105821A3
The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts.The novel compounds (i) 10,11-Anhydro-2',4"-di-O-benzoyl-12-O-imidazolylcarbonyl-6-O -methylerythromyci...  
WO/2006/039263A2
The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: (I) (II) which exhibit antibacterial properties. The present invention further relates to pharmaceutical c...  
WO/2006/037159A1
A method of identifying biologically active compounds with defined selectivity profile comprises: (c) designing a library of compounds of formula (1) to scan molecular diversity; and (d) assaying the library of compounds in at least two ...  
WO/2006/035301A2
The present invention provides acylide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed to by Gram-positive, Gram-negative or an...  
WO/2006/033412A1
An alleviator for radiation disorders which is safe even when administered to the living body; and a composition containing the alleviator for radiation disorders. The alleviator for radiation disorders contains &agr -D-glucopyranosyl-(1...  
WO2005061524A3
The present invention provides an efficient process for the preparation of polymorphic Form I and II of clarithromycin. The process includes drying wet clarithromycin obtained after purification in the presence of nitrogen gas and in the...  
WO/2006/025051A2
The present invention provides a process of preparing a crystalline azithromycin monohydrate. The process involves dissolving azithromycin in a solution containing ethanol, adding the dissolved azithromycin into water to precipitate the ...  
WO/2006/024405A2
A compound of the formula (I) wherein the bond between carbon atoms 22 and 23 indicated with a broken line is a single or double bond, n is 0, 1 or 2, R1 represents, for instance, a C1-C12alkyl group, R2 represents, for instance, R15 gro...  
WO/2006/022174A1
The invention aims at providing a method for inhibiting the browning and/or stinking of a composition and thus improving the storage stability of the composition. The aim is attained by a method which comprises adding a browning inhibito...  
WO/2006/020712A1
A method of generating synthetic metabolites of tanaproget derivatives thereof is provided. These compounds and methods of using these derivatives for detecting tanaproget metabolites in samples are provided.  
WO/2006/017250A2
Sixteen membered macrolide anti-infective agents having a structure according to formula (I) where R1, R2, R3, R4, R5, and R6 are as defined herein, and related compounds are disclosed.  
WO2005121160A3
The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disc...  
WO/2006/013409A1
The present invention provides acylide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for the treatment or prevention of a condition caused by or contributed to by Gram-positive, Gram-negat...  
WO/2006/011561A1
Disclosed is a medicament for treating and/or preventing diabetes and the like which has excellent activity and safety. Specifically disclosed is a compound represented by the general formula (I) below or a pharmacologically acceptable s...  
WO/2006/011160A1
The present invention relates to an improved, cost effective and easy process for the preparation of azithromycin monohydrate isopropanol clathrate. The process provides a one-step method of preparing azithromycin monohydrate isopropanol...  
WO2005085266A3
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2004073658A3
Isoflavones are modified by esterification at one or more of the C4', C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications prod...  
WO/2005/123711A1
The present invention relates to pharmaceutics and organic chemistry. The invention discloses a new kind of bicyclol glycosides and the preparation method thereof. The method comprises bicyclol being reacted with trichloroimide ester of ...  
WO/2005/121161A1
The invention relates to substituted fluoroglycoside derivatives of pyrazoles of formula (I), in which the radicals have the indicated meanings, to the physiologically compatible salts thereof, and to a method for the production thereof....  
WO/2005/121160A2
The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disc...  
WO/2005/118610A2
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2005012318A3
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.  
WO2005018576A3
Compounds having the structure of formula I: wherein R<1>,R<2>,R<3>, R<4>, R<5>, and R<6> are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility.  
WO2002079150A3
The present invention provides combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. Th...  
WO2005080549A3
The invention relates to the use of trioxacarcins as agents for treating infections caused by fungi, parasites, viruses or bacteria. The invention also relates to the novel trioxacarcin derivatives as such, to drugs containing them or th...  
WO2005085266A8
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2005053650A8
An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multipar...  
WO/2005/112951A1
It is intended to provide an antitumor agent, which has established a strengthened function selectivity of acting exclusively on caner cells, lessened side effects, mastery of drug tolerance and so on, and has an activity of inducing cel...  
WO/2005/111055A1
Kigamicins A, B, C, D and E represented by the following general formula (I) wherein R represents a sugar chain selected from among the sugar chain of the following formula: and other various sugar chains; are obtained as novel antibioti...  
WO2005070427A8
The invention relates to the use of a monoamine neurotransmitter re-uptake inhibitor comprising a 2,3-disubstituted tropane moiety, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative ther...  
WO2005081821A3
The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are ...  
WO/2005/108414A1
The present invention provides novel crystalline forms of the macrolide antibiotic 9-(S)-erythromycylamine, and methods of preparing and using the same.  
WO/2005/108413A1
The present invention relates to 14- or 15-membered macrolides substituted at the 4' position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis ...  
WO2005012242A3
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of d...  
WO/2005/108412A1
The present invention relates to 14- or 15-membered macrolides substituted at the 4” position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxi...  
WO2005034846A3
Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources....  
WO/2005/105821A2
The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts.The novel compounds (i) 10,11-Anhydro-2',4'-di-O-benzoyl-12-O-imidazolylcarbonyl-6-O -methylerythromyci...  
WO2005067564A3
The present invention discloses compounds of formulaes I, II, III, or IV, or a 5 racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: which exhibit antibacterial properties. The present invention further relates to pharmace...  

Matches 701 - 750 out of 6,658