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Patent Searching and Data


Matches 701 - 750 out of 6,631

Document Document Title
WO/2006/039263A2
The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: (I) (II) which exhibit antibacterial properties. The present invention further relates to pharmaceutical c...  
WO/2006/037159A1
A method of identifying biologically active compounds with defined selectivity profile comprises: (c) designing a library of compounds of formula (1) to scan molecular diversity; and (d) assaying the library of compounds in at least two ...  
WO/2006/035301A2
The present invention provides acylide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed to by Gram-positive, Gram-negative or an...  
WO/2006/033412A1
An alleviator for radiation disorders which is safe even when administered to the living body; and a composition containing the alleviator for radiation disorders. The alleviator for radiation disorders contains &agr -D-glucopyranosyl-(1...  
WO2005061524A3
The present invention provides an efficient process for the preparation of polymorphic Form I and II of clarithromycin. The process includes drying wet clarithromycin obtained after purification in the presence of nitrogen gas and in the...  
WO/2006/025051A2
The present invention provides a process of preparing a crystalline azithromycin monohydrate. The process involves dissolving azithromycin in a solution containing ethanol, adding the dissolved azithromycin into water to precipitate the ...  
WO/2006/024405A2
A compound of the formula (I) wherein the bond between carbon atoms 22 and 23 indicated with a broken line is a single or double bond, n is 0, 1 or 2, R1 represents, for instance, a C1-C12alkyl group, R2 represents, for instance, R15 gro...  
WO/2006/022174A1
The invention aims at providing a method for inhibiting the browning and/or stinking of a composition and thus improving the storage stability of the composition. The aim is attained by a method which comprises adding a browning inhibito...  
WO/2006/020712A1
A method of generating synthetic metabolites of tanaproget derivatives thereof is provided. These compounds and methods of using these derivatives for detecting tanaproget metabolites in samples are provided.  
WO/2006/017250A2
Sixteen membered macrolide anti-infective agents having a structure according to formula (I) where R1, R2, R3, R4, R5, and R6 are as defined herein, and related compounds are disclosed.  
WO2005121160A3
The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disc...  
WO/2006/013409A1
The present invention provides acylide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for the treatment or prevention of a condition caused by or contributed to by Gram-positive, Gram-negat...  
WO/2006/011561A1
Disclosed is a medicament for treating and/or preventing diabetes and the like which has excellent activity and safety. Specifically disclosed is a compound represented by the general formula (I) below or a pharmacologically acceptable s...  
WO/2006/011160A1
The present invention relates to an improved, cost effective and easy process for the preparation of azithromycin monohydrate isopropanol clathrate. The process provides a one-step method of preparing azithromycin monohydrate isopropanol...  
WO2005085266A3
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2004073658A3
Isoflavones are modified by esterification at one or more of the C4', C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications prod...  
WO/2005/123711A1
The present invention relates to pharmaceutics and organic chemistry. The invention discloses a new kind of bicyclol glycosides and the preparation method thereof. The method comprises bicyclol being reacted with trichloroimide ester of ...  
WO/2005/121161A1
The invention relates to substituted fluoroglycoside derivatives of pyrazoles of formula (I), in which the radicals have the indicated meanings, to the physiologically compatible salts thereof, and to a method for the production thereof....  
WO/2005/121160A2
The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disc...  
WO/2005/118610A2
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2005012318A3
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.  
WO2005018576A3
Compounds having the structure of formula I: wherein R<1>,R<2>,R<3>, R<4>, R<5>, and R<6> are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility.  
WO2002079150A3
The present invention provides combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. Th...  
WO2005080549A3
The invention relates to the use of trioxacarcins as agents for treating infections caused by fungi, parasites, viruses or bacteria. The invention also relates to the novel trioxacarcin derivatives as such, to drugs containing them or th...  
WO2005085266A8
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO2005053650A8
An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multipar...  
WO/2005/112951A1
It is intended to provide an antitumor agent, which has established a strengthened function selectivity of acting exclusively on caner cells, lessened side effects, mastery of drug tolerance and so on, and has an activity of inducing cel...  
WO/2005/111055A1
Kigamicins A, B, C, D and E represented by the following general formula (I) wherein R represents a sugar chain selected from among the sugar chain of the following formula: and other various sugar chains; are obtained as novel antibioti...  
WO2005070427A8
The invention relates to the use of a monoamine neurotransmitter re-uptake inhibitor comprising a 2,3-disubstituted tropane moiety, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative ther...  
WO2005081821A3
The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are ...  
WO/2005/108414A1
The present invention provides novel crystalline forms of the macrolide antibiotic 9-(S)-erythromycylamine, and methods of preparing and using the same.  
WO/2005/108413A1
The present invention relates to 14- or 15-membered macrolides substituted at the 4' position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis ...  
WO2005012242A3
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of d...  
WO/2005/108412A1
The present invention relates to 14- or 15-membered macrolides substituted at the 4” position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxi...  
WO2005034846A3
Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources....  
WO/2005/105821A2
The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts.The novel compounds (i) 10,11-Anhydro-2',4'-di-O-benzoyl-12-O-imidazolylcarbonyl-6-O -methylerythromyci...  
WO2005067564A3
The present invention discloses compounds of formulaes I, II, III, or IV, or a 5 racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: which exhibit antibacterial properties. The present invention further relates to pharmace...  
WO2005070113A3
The present invention discloses compounds of formula (I), (II), (III), or (IV), or a racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: formulas (I), (II), (III), (IV), which exhibit antibacterial properties. The present ...  
WO2004110255A3
The present invention relates to novel antineoplastic agents and cancer diagnostic agents that specifically target neoplastic cells via the GLUT transportation system. More specifically, the invention relates to conjugates of 2­-deoxygl...  
WO2005072204A3
Compounds of Formula (I), and pharmaceutically acceptable salts, esters, and prodrugs thereof: (I) are disclosed, wherein A, B, D, L, X, Y, Z and R2' are described herein. The compounds exhibit antibacterial properties. The compounds of ...  
WO2003106413A3
A process for preparing N-(substituted)-C­- (substituted methyl)-oxazolidinones, C-(substituted methyl)-oxazolidinones, and N-(substituted)-C­- (substituted ethyl)-oxazolidinones, preferably chiral, from optically active C-(protected o...  
WO2004028481A3
Disclosed are compounds, compositions and methods for treating hepatitis C virus infections.  
WO/2005/097106A1
Compositions of purified and biologically active ellagitannins, including punicalagin, are provided by separation from pomengranate husk using a method of extraction and purification using a solid polymeric adsorbent.  
WO2005009398A3
The invention relates to Tetracyclic Benzamide Derivatives; compositions comprising a Tetracyclic Benzamide Derivative; and methods for treating or preventing an inflammatory disease, a reperfusion disease, an ischemic condition, renal f...  
WO/2005/090377A1
The present invention relates to a process for the production of clarithromycin using solvents with a low toxic potential and water.  
WO/2005/087787A1
The 2-fluoro-6-O-substituted ketolide derivative represented by the formula [Chemical formula 1] (1) or a pharmaceutically acceptable salt or hydrate thereof. They are new erythromycin derivatives which have potent antibacterial activity...  
WO/2005/087786A1
The invention relates to: (i) the use of osyl derivatives of genkwanin and sakuranetin having formula (I) in (a) cosmetics or dermatology and (b) therapeutics; (ii) the use of novel derivatives having formula (I) as industrial products; ...  
WO/2005/085266A2
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.  
WO/2005/084689A1
The invention discloses a Radix astragli extract and production method and use thereof. Such Radix astragli extract mainly comprises astragalus saponin, organic acid and astragalus flavonoid glycoside. Such production method consists of ...  
WO/2005/085223A1
A medicine, functional food, or health food which are effective in the prevention and/or treatment of bone diseases, and contain as an active ingredient a safe flavonoid compound derived from a natural material. Also provided is a medici...  

Matches 701 - 750 out of 6,631