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WO/2005/062923A2 |
The present invention provides genetically manipulated cells and methods for utilizing same. Methods of enhanced carotenoid synthesis utilizing cells genetically disrupted for a yjiD, hnr or yifP gene, or further disrupted for a gdhA, gp...
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WO/2005/056757A2 |
A method for the positive selection of allelic exchange mutants is provided for C1 metabolizing bacteria. The chromosomal integration vectors, based on the pGP704 suicide vector, comprise at least one genetic selectable marker and the sa...
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WO/2005/049643A1 |
A peptide obtained from Brevundimonas strain SD-212 and having a β-ionone ring-2-hydroxylase activity; and a gene coding for the same. Thus, it becomes feasible to realize mass production of a carotenoid having hydroxyl introduced at th...
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WO/2005/044975A2 |
A unique carotenogenic biosynthetic gene cluster has been isolated from Panteoa agglomerans strain DC404, wherein the genetic organization of the cluster is crtE-idi-crtY-crtI-crtB-crtZ. The genes contained within this cluster encode ger...
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WO/2005/030976A2 |
The invention relates to the production of a carotinoid-containing biomass. The aim of the invention is to provide a method for producing carotinoid-containing biomass that can be realized with a low level of complexity on a large scale ...
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WO/2005/028661A1 |
A process for producing zeaxanthin, β-carotene or lycopene which comprises mutagenizing a carotenoid-producing microorganism the DNA base sequence of which corresponding to 16S ribosomal RNA is substantially homologous with the base seq...
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WO/2005/026739A2 |
A method of increasing a fraction of free carotenoids in a source of carotenoids in which at least some of the carotenoids are fatty acid esterified carotenoids is disclosed. The method is effected by contacting the source of carotenoids...
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WO/2005/019426A2 |
Domains of fostriecin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare fostriecin in pharmaceutically useful quantities are described, as are methods to prepare fostriecin an...
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WO/2005/019467A1 |
The invention relates to a method for producing ketocarotinoids by cultivation of genetically modified organisms that have a modified ketolase activity and modified $g(b)-cyclase activity as compared to the wild-type organism. The invent...
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WO/2005/019461A2 |
The invention relates to a method for producing ketocarotinoids by cultivation of genetically modified, non-human organisms that have a modified ketolase activity as compared to the wild-type organism. The invention also relates to the g...
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WO/2005/019460A2 |
The invention relates to the use of promoters selected from the group including A) EPSPS promoter, B) B-gene promoter, C) PDS promoter and D) CHRC promoter for the expression, preferably for the flower-specific expression, of genes in pl...
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WO/2005/010156A2 |
A carotenogenic biosynthetic gene cluster has been isolated from Panteoa stewartii strain DC413, wherein the genetic organization of the cluster is crtE-idi-crtX-crtY-crtI-crtB-crtZ. The genes contained within this cluster encode geranyl...
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WO/2005/007826A2 |
A method for the in vivo bioconversion of cyclic carotenes having a β-ionone ring to the corresponding aryl carotene is provided. Gram negative host cells expressing a heterologous, codon-optimized gene encoding a carotene desaturase ar...
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WO2001096591A9 |
A process for the microbial production of a plural number of carotenoid compounds wherein the ratio of the carotenoid compounds thus formed is varied. The ratio of the carotenoid compounds thus formed (astaxanthin, adonixanthin, beta -ca...
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WO/2005/001024A2 |
Genes have been isolated from Pectobacterium cypripedii encoding geranylgeranyl pyrophosphate (GGPP) synthase (CrtE), phytoene synthase (CrtB), phytoene desaturase (CrtI), lycopene cyclase (CrtY), β-carotene hydroxylase (CrtZ), and zeax...
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WO/2004/104180A2 |
Genes have been isolated from strain DC260, a member of the Enterobacteriaceae family, encoding geranylgeranyl pyrophosphate (GGPP) synthetase (CrtE), phytoene synthase (CrtB), phytoene desaturase (Crtl), lycopene cyclase (CrtY), β-caro...
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WO/2004/101746A2 |
Microorganisms containing one or more exogenous nucleic acids and producing detectable amounts of carotenoids are described.
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WO/2004/087892A1 |
The present invention relates to a gene involved in the biosynthesis of carotenoid and a marine microorganism producing the carotenoid, more particularly to a gene represented by Seq ID. No. 5, 7, 9, 11, 13 and 15 which encoding the prot...
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WO/2004/074490A2 |
The present invention relates to the production of a molecule of interest by a host cell. Provided is a method for producing at least one molecule of interest by a host cell, comprising providing a host cell with at least one isolated nu...
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WO/2004/070021A1 |
The invention relates to a method of obtaining a biomass of lutein-rich Muriellopsis microalga through the culture thereof in an open pond system which is agitated and exposed to adverse weather. The inventive method can be used to achie...
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WO/2004/067780A1 |
Accordingly the present invention provides a process for the preparation an alcoholic extract with Carotenoids, UV absorption, antibacterial and pH indicating properties from a deep-sea bacterium which comprises a method for growing the ...
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WO/2004/063358A1 |
The invention relates to a method for producing a genetically modified organism of the genus Blakeslea, said method comprising the following steps: (i) at least one of the cells is transformed, (ii) the cells obtained in step (i) are opt...
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WO/2004/063366A1 |
The invention relates to a method for producing ketocarotenoids by cultivating genetically modified organisms that have a modified ketolase activity in relation to the wild type. The invention also relates to said genetically modified or...
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WO/2004/063359A2 |
The invention relates to a method for producing carotenoids or their precursors using genetically modified organisms of the Blakeslea genus. Said method comprises the following steps (i) transformation of at least one of the cells, (ii) ...
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WO/2004/058951A1 |
Mutations in chromosomal genes have been identified that affect plasmid copy number in plasmids that are anti-sense RNA regulated such as the pMB1-derived and p15A-derived plasmids.
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WO/2004/056974A2 |
Mutations in genes having no direct relationship to the carotenoid biosynthetic pathway have been found to increase carbon flux through that pathway. Complete disruption in the deaD, mreC, and yfhE genes were effective. Additionally wher...
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WO/2004/056972A2 |
The invention describes a method for the stacking of traits in a recombination proficient host using a phage transduction system. The method makes use of a nucleic acid integration cassette that has homology to a specific site on a host ...
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WO/2004/057012A1 |
The invention is applicable in medicine, various branches of the food processing industry, and farming. The objective of invention is a selection of high-yield strain - producer of (ß - carotene, with more effective biomass accumulation...
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WO/2004/056975A2 |
The present invention relates to carotenoid overproducing bacteria. The genes of the isoprenoid pathway in the bacterial hosts of the invention have been engineered such that certain genes are either up-regulated or down regulated result...
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WO/2004/048589A1 |
The present invention relates to the isolation of compounds such as carotenoids and flavonoids, in particular the highly oxidised carotenoid astaxanthin (astaxanthin, 3,3'-5dihydroxy-β,β-carotene-4, 4'-dione), and the flavonoid anthocy...
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WO/2004/029261A2 |
Disclosed is a process for producing canthaxanthin and echinenone which comprises cultivating a recombinant microorganism which is expressing a ß-carotene ketolase gene and belonging to the genus Xanthophyllomyces (Phaffia) in an aqueou...
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WO/2004/029232A2 |
The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as animals, algae and microorganisms. It has ...
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WO/2004/029275A1 |
Disclosed is a process for producing zeaxanthin and ß-cryptoxanthin which comprises cultivating a recombinant microorganism which is expressing a ß-carotene hydroxylase gene and belonging to the genus Xanthophyllomyces (Phaffia) in an ...
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WO/2004/029234A1 |
Disclosed are novel DNA fragments encoding the enzymes, from Arabidopsis thaliana and Glycine max. The said DNA means a cDNA which contains only open reading frame flanked between the short fragments in its 5'- and 3'-untranslated region...
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WO/2004/029255A2 |
The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as animals, algae and microorganisms. It has ...
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WO/2004/029260A2 |
Disclosed is a fermentation method of astaxanthin using Phaffia rhodozyma comprising the steps of: (a) in the growing phase, feeding of a nutrient medium containing glucose or sucrose based on the specific growth rate (µ) of Phaffia rho...
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WO/2004/022765A2 |
The invention relates to a method for hydrolysing enzymatic carotenoids esters and the use of said carotenoids and the products thereof as human and animal food.
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WO/2004/018385A2 |
The invention relates to a method for the production of zeaxanthin and/or the biosynthetic intermediates and/or subsequent products thereof by the cultivation of genetically-altered plants which have a reduced $g(e)-cyclase activity in c...
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WO/2004/018695A2 |
The invention relates to a method for producing ketocarotinoids by cultivating genetically modified plants which exhibit a ketolase activity in the fruit thereof.
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WO/2004/017749A2 |
The invention relates to the use of astaxanthin-containing plants or parts of plants of the genus Tagetes or astaxanthin-containing extracts of astaxanthin-containing plants or parts of plants of the genus Tagetes for oral administration...
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WO/2004/018693A2 |
The invention relates to a method for the production of ketocarotinoids by means of the cultivation of plants, which have an altered ketolase activity in flower petals in comparison to the wild type, the genetically altered plants and th...
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WO/2004/018688A1 |
The invention relates to a method for the production of $g(b)-carotinoids by the cultivation of genetically-modified plants, the genetically-modified plants and the use thereof as human and animal foodstuffs and for the production of $g(...
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WO/2004/018694A2 |
The invention relates to a method for producing ketocarotinoids by cultivating genetically modified organisms having a modified ketolase activity compared to the wild type, to genetically modified organisms, and to the use thereof as foo...
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WO/2004/013345A1 |
The invention relates to a method for the biotransformation of carotenoids using enzymes having a cytochrome P450 monooxygenase activity, especially monooxygenases of thermophilic bacteria, especially the genus Thermus sp.
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WO/2004/001057A1 |
The present invention relates to a biological process for producing carotenoids utilizing a microorganism which is capable of producing carotenoids and belonging to the genus Xanthophyllomyces (Phaffia) in the presence of an inhibitor fo...
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WO/2003/104183A1 |
The invention relates to cosmetic and/or pharmaceutical preparations containing esters of retinol and/or of 3,4-di-dehydro-retinol according to formulas (I) or (II) or (III) or (IV), in which: groups R1 to R5, independent of one another,...
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WO/2003/095397A2 |
The invention relates to a method for extracting carotenoids from a carotenoid producing viable cell. The method comprises milking the cell in a culture medium consisting essentially of an aqueous phase and an biocompatible organic phase...
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WO/2003/093229A1 |
An astaxanthin medium-chain fatty acid ester whose application can be expected in the fields of food, cosmetic and drug and which is superior in digestion absorptivity and tissue transition capability to the astaxanthin of long-chain fat...
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WO/2003/093200A2 |
A method for the production of aryl-carotenoids is provided through bioconversion of cyclic carotenoids having at least one β-ionone ring. Expression of a heterologous gene encoding a carotene desaturase (crtU) enzyme in a host cell tha...
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WO/2003/087358A1 |
A process for producing canthaxanthin characterized by comprising mutagenizing an astaxanthin-producing microorganism the base sequence of DNA corresponding to 16S ribosomal RNA of which is substantially homologous with the base sequence...
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