| Document |
Document Title |
|
WO/2011/131027A1 |
Preparation methods of L-phenylephrine hydrochloride by a major step of asymmetric hydrogenation and a series of special subsequent steps are provided, wherein, ruthenium-containing BINAP catalyst systems are used as the asymmetric hydro...
|
|
WO/2011/124190A2 |
A method of producing 4-(2-(substituted)-l-(l-hydroxycyclohexyl)ethyl)phenols of general formula (I), wherein the symbols R1 and R2 are hydrogen (H) or methyl (CH3), by demethylation of their methylethers of general formula (II), wherein...
|
|
WO/2011/120822A1 |
A fabric softener active composition, comprising at least 0 % by weight of a bis-(2-hydroxypropyl)-dimethylammonium 5 methylsulphate fatty acid ester having a molar ratio of fatty acid moieties to amine moieties of from 1.5 to 1.99, wher...
|
|
WO/2011/113926A1 |
The invention relates to a method for producing tin alkoxides. In particular, the invention relates to a method for directly synthesizing tin alkoxides of the general formula Sn(OR)n, where n = 2 or 4, from elemental tin by reacting the ...
|
|
WO/2011/115803A1 |
Provided is a process for making an aminoalcohol compound. The process comprises using an excess amount of aliphatic aldehyde in a condensation step between the aldehyde and a nitroalkane, and using an aldehyde scavenger in a reductive h...
|
|
WO/2011/110556A1 |
A process is described for the preparation of intermediates which can be used for preparation of agents for urinary incontinence therapy, specifically to 2-(3-(diisopropylamino)- 1-phenylpropyl)-4-(hydroxymethyl)phenol and its prodrugs.
|
|
WO/2011/107876A2 |
Provided herein is an improved and industrially advantageous optical resolution method for resolving (2R,3R)/(2S,3S)-l-dimethylamino-3-(3-methoxyphenyl)-2- methylpentan-3-ol, and use thereof for the preparation of tapentadol or a pharmac...
|
|
WO/2011/105088A1 |
Disclosed is a novel diamine compound, shown in equation (1). In equation (1), A represents an aromatic group (number of rings 4 or less) or a divalent aliphatic group (carbon number 10 or less) with an optional substituent. The disclose...
|
|
WO/2011/099810A2 |
The present invention relates to a method for preparing a cationic surfactant containing a compound of chemical formula 1, wherein the method comprises performing esterification on monomeric acid and triethanolamine or methyl dimethylami...
|
|
WO/2011/092538A1 |
Amine stabilizing agents containing an azeotrope comprising water, an alcohol, and sodium hydride. Amine stabilizing agents containing water and a liquid silica hydroxide compound. Methods of making of amine stabilizing agents where soli...
|
|
WO/2011/091197A2 |
The invention provides a method of continuously producing high quality quaternized N,N-dialkylaminoethyl (meth)acrylates (DMAEA-MCQ) that has a long shelf life and which is stable in water. The method involves placing starting marterials...
|
|
WO/2011/086115A2 |
The invention relates to a compound comprising a pesticide and an alkoxylate. The invention further relates to the alkoxylate, to a method for the production thereof, and to the use thereof as an auxiliary agent in pesticide-containing s...
|
|
WO/2011/087793A1 |
The present invention relates to an etheramine mixture containing a monoether diamine and its method of production by alkoxylating an initiator with an alkylene oxide to produce a precursor polyol and reductively aminating the precursor ...
|
|
WO/2011/082994A1 |
The present invention relates to a method for reacting glycolaldehyde with an aminizing agent in the presence of hydrogen and a catalyst, the catalyst being activated by reducing a catalyst precursor or by reducing a passivated catalyst,...
|
|
WO/2011/084719A2 |
Novel macromolecules for filtering contaminants from water and non-aqueous solutions. Molecules such as polyethyleneimine (PEI) may be functionalized, cross-linked, and/or quaternized to improve their binding capacity or selectivity with...
|
|
WO/2011/084789A2 |
An integrated process is provided for efficiently preparing 2,4,5-triaminophenol, starting with nitration of 2,6-dihalobenzene; high purity salts thereof; and complexes of 2,4,5-triaminophenol aromatic diacids, which are precursors for m...
|
|
WO/2011/084765A2 |
A method to synthesize choline salts to be used as inexpensive ingredients for application in ionic liquids or other applications is disclosed.
|
|
WO/2011/078302A1 |
Disclosed is a method for producing an N-alkyl-β-valienamine analogue represented by the formula (1) (wherein R1 is an alkyl group with carbon number 1-12). Further disclosed is a novel intermediate product useful in said production met...
|
|
WO/2011/075966A1 |
Disclosed is a method for synthesizing 3-methylamino-1,2-propylene glycol, which includes the following steps: (1) feeding chloro-glycerin, an aqueous solution of monomethylamine and an aminating catalyst, NaOH solution and NaHCO3, into ...
|
|
WO/2011/073362A1 |
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmet...
|
|
WO/2011/068209A1 |
Disclosed are: a composition containing an intermediate for a water-soluble monomer, which can be used suitably for the production of a water-soluble poly(alkylene glycol) monomer that has a polymerizable double bond at the terminal, can...
|
|
WO/2011/067714A1 |
The present invention refers to a new process for the synthesis of tapentadol comprising the quantitative resolution of the racemic mixture (V) to obtain the stereoisomer of (S)-3-(dimethylamino)-2-methyl-l-(3-nitrophenyl)-propan-l-on
e ...
|
|
WO/2011/065420A1 |
Provided is a novel method for manufacturing a 6-substituted-1-methyl-1H-benzimidazole derivative. Also provided is a manufacturing intermediate from said method. The provided method, which manufactures a 6-substituted-1-methyl-1H-benzim...
|
|
WO/2011/056841A1 |
Embodiments of methods for preparing 3-aminopicric acid from picric acid is described. In one embodiment, the method comprises combining lithium hydroxide, picric acid, and a first solvent to form a first solution, combining lithium hydr...
|
|
WO/2011/056929A1 |
The present invention provides various methods for the synthesis of chemical species in a microreactor environment. In some cases, reaction products of the present invention may be valuable as intermediates and/or products in pharmaceuti...
|
|
WO/2011/051853A1 |
The invention describes a novel technical process and novel intermediates useful for the manufacture of enantiomerically pure 8- aryloctanoic acids of the formula (I) which are pharmaceutically active compounds as rennin inhibitors.
|
|
WO/2011/048535A1 |
The process of the present invention creates a sustainable and closed water loop allowing inherent recycles of all liquid streams generated in the process. The liquid streams generated during the process of the invention are inherently r...
|
|
WO/2011/048727A1 |
Provided is a ruthenium carbonyl complex represented by general formula (1). (1) RuXY(CO)(L) (In general formula (1), X and Y represent anionic ligands and may be the same as each other or different from each other; and L represents a tr...
|
|
WO/2011/042916A1 |
The invention relates to a process for the production of 2AEE with selectivity towards 2AEE being significantly higher i.e. the ratio of 2AEE: morpholine > 3. DEG and Ammonia are reacted in a continuous mode in hydrogen atmosphere in the...
|
|
WO/2011/044478A1 |
A method for preparing a compound having formula (II): wherein R1 and R2 independently are methyl or ethyl, or R1 and R2 combine to form a C5 or C6 cycloalkyl or cycloalkenyl group. The method includes a step of combining R1R2CHNO2, glut...
|
|
WO/2011/035725A1 |
Disclosed are sitagliptin intermediates, preparation methods and uses thereof. Said preparation methods are that compound of formula (I) is prepared by Grignard reacting compound of formula (II), trifluorobromobenzene and Grignard reagen...
|
|
WO/2011/032476A1 |
A method for preparing levo-betaxolol hydrochloride is provided. The method includes using p-hydroxyl phenyl ethanol as starting material and obtaining the pure levo-betaxolol hydrochloride by selectively esterifying alcoholic hydroxyl, ...
|
|
WO/2011/026314A1 |
The preparation method of tapentadol and intermediates thereof are provided. The intermediates are the compounds represented by formula (II), their enantiomorphs, diastereomers, recemes, salts or the mixture thereof.
|
|
WO/2011/022429A2 |
The present invention relates to a process for the preparation of alkyl esters of (S) 2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)-N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-diflu...
|
|
WO/2011/017510A2 |
The present invention relates to a method for synthesizing amonoalcohols (e.g., aminoalcohols that contain an amine group that is either unsubstituted, mono-substituted, or di-substituted) and to the products formed therefrom. In one emb...
|
|
WO/2011/012777A1 |
The degradation of an absorbent solution comprising organic compounds provided with an amino functional group in aqueous solution is substantially reduced in the presence of a small amount of degradation-inhibiting agents belonging to th...
|
|
WO/2011/013108A1 |
The present invention provides a polymorphic form of toremifene citrate and processes for its preparation. It also relates to an improved process for the preparation of the Z isomer of the toremifene base, free of E isomer, and its pharm...
|
|
WO/2011/012584A1 |
The invention relates to a process for obtaining 3,3- diphenylpropylamines of general formula (I), particularly Fesoterodine, as well as their enantiomers, solvates and salts, comprising a chemoselective reduction of the acid group again...
|
|
WO/2011/009634A2 |
The invention relates to a process for producing pharmaceutically acceptable salts of fingolimod (I), comprising the step of reacting N-[1,1-bis hydroxymethyl-3-(4-octyl phenyl)-propyl]-acylamide (II) with an acidic compound. Furthermore...
|
|
WO/2011/011352A1 |
An unsaturated quaternary ammonium salt is produced by a process that includes reacting methyl chloride in a first vessel with a stoichiometric excess of an unsaturated tertiary amine in the presence of water to form a reaction mixture t...
|
|
WO/2011/007877A1 |
Disclosed are: a method for producing an optically active epoxy compound; a ligand which is used in the method; a complex; a method for producing the ligand; and a method for producing the complex. Specifically disclosed are: a complex w...
|
|
WO/2011/006455A2 |
A method for the preparation of 4-(2-(dimethylamino)-l-(l-hydroxycyclohexyl)ethyl) phenol of formula (I), known under generic name desvenlafaxine, and its pharmaceutically acceptable salts, which comprises (a) mixing of the starting mate...
|
|
WO/2010/149936A1 |
The present invention relates to a process for preparing alkylalkanolamines, comprising the reaction of a carbonyl-based compound with a hydroxylalkylamine, in the presence of hydrogen and a catalyst.
|
|
WO/2010/139520A1 |
According to the present invention, a method for separating a primary amine being an N,N- dialkylbisaminoalkylether, from mixtures comprising said primary amine and at least one of a secondary amine being an N,N,N'-trialkylbisaminoalkyle...
|
|
WO/2010/139521A1 |
A method for providing a secondary or tertiary amine with formula (R1R2NR3)2NR4 is provided, wherein each of R1 and R2 are chosen from the group consisting of a methyl group, an ethyl group, an iso-propyl group and an n-propyl group; R3 ...
|
|
WO/2010/135092A2 |
A method and apparatus for preparing a N,N-dialkylaminoalkyl acrylate in a continuous transesterification reaction. The reaction involves adding alkyl acrylates such as methacrylate or ethacrylate to a reboiler mechanism and efficiently ...
|
|
WO/2010/125923A1 |
Disclosed is a polymer-supported catalyst in which a group 8-11 metal of the periodic table is supported by a polymer carrier represented by formula (1a), preferably a polymer carrier represented by formula (1b). (In the formulae, A repr...
|
|
WO/2010/126003A1 |
A germination promoter for Nomuraea rileyi which comprises, as the active ingredient, a sphingosine capable of promoting the germination of N. rileyi, more specifically, at least one sphingosine selected from the group consisting of sphi...
|
|
WO/2010/115639A1 |
A process for the preparation of the compound of formula (I).
|
|
WO/2010/114291A2 |
The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used...
|
