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Matches 1 - 50 out of 32,233

Document Document Title
WO/2018/218281A1
A process for inhibiting the formation of gas hydrates in a hydrocarbon fluid comprising adding to the hydrocarbon fluid, a gas hydrate anti-agglomerate which is a biodegradable anti-agglomerant derived from a naturally occurring substance.  
WO/2018/220003A1
The present invention relates to a process for the hydrogenation of a composition comprising hydroxymethylfurfural, bishydroxymethylfuran or mixtures thereof to obtain a composition comprising cis-(tetrahydrofuran-2,5-diyl)dimethanoland ...  
WO/2018/220634A1
The invention generally provides a method for the synthesis of a π-conjugated system from oligofurans, under conditions involving cycloaddition.  
WO/2018/222444A1
Embodiments of the disclosure relate to methods of selectively depositing organic and hybrid organic/inorganic layers. More particularly, embodiments of the disclosure are directed to methods of modifying hydroxyl terminated surfaces for...  
WO/2018/215818A1
The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and...  
WO/2018/214961A1
The present invention belongs to the field of medicinal chemistry. Specifically disclosed is a class of URAT1 inhibitors for promoting uric acid excretion, which are compounds as represented by the structure of formula (I) or pharmaceuti...  
WO/2018/214676A1
The present invention provides a method suitable for mass-producing a buagafuran active pharmaceutical ingredient. A buagafuran active pharmaceutical ingredient with high purity can be prepared by the method and can be applied to a new d...  
WO/2018/216030A1
The present invention discloses a single step process for the synthesis of furan derivative from carbohydrate comprises stirring the reaction mixture of carbohydrate in solvent in presence of catalyst at temperature in the range of 170 t...  
WO/2018/217894A1
The invention relates to halichondrin derivatives containing fluorine, e.g., fluorine-18, as well as methods of synthesizing the same.  
WO/2018/209616A1
Provided are an α-amino acrylate microbicide, and a preparation method therefor and uses thereof. Based on the principle of pesticide molecular design, the structural reform of the agricultural anti-plant virus activity is carried on le...  
WO/2018/209973A1
The present invention provides compounds as represented by structural formula (I), its S-isomers and R-isomers, and its pharmaceutically acceptable salts. In formula (I), R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 ar...  
WO/2018/213236A1
The present invention relates to the unexpected discovery of novel multi-aromatic, multi-substituted compounds. In certain embodiments, the compounds of the invention are generated by condensing at least two phenolic- and/or aniline-cont...  
WO/2018/211516A1
The present application relates to derivatives of tricyclic spirolactones compounds of formula (I) and compositions thereof and uses thereof in treatment and management of pain. Formula (I).  
WO/2018/213150A1
The application relates to phenyl- or naphthylsulfonamide derivatives of the structural formula (I). The compounds are described as inhibitors of USP30 (ubiquitin specific peptidase 30) useful for the treatment of conditions involving mi...  
WO/2018/209972A1
The present invention provides compounds as represented by structural formula (I). In formula (I), R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are separately H or deuterium (D) independently. Moreover, at least one of...  
WO/2018/210297A1
Disclosed are an intermediate of Eribulin and a preparation method therefor. In particular, disclosed are compounds as represented by formula II, formula III and formula V and a preparation method therefor. Ar is C1-10 alkyl substituted,...  
WO/2018/213442A1
A diastereoselective method of preparing benzofuran-based 4,5-spirocycles via metal catalyzed alkenylation is described. The method can be used to provide compounds containing the benzofuranone-4,5-spirocyclic motif of the phainanoids, a...  
WO/2018/209665A1
A preparation method for a nano-nickel-based catalyst with a confinement structure and hexahedral morphology. According to the method, a nickel-aluminum hydrotalcite precursor of an organic carbon chain intercalation is synthesized first...  
WO/2018/207888A1
The present invention provides a method for simply and efficiently producing ramelteon, which is a sleep-inducing agent. According to the present invention, ramelteon can be produced through a few steps including a step in which (E)-2-[1...  
WO/2018/207812A1
The purpose of the present invention is to provide therapeutic agents for bedsore and skin wound and methods for treating bedsore and skin wound. The present invention provides a bedsore therapeutic agent or a bedsore treatment method or...  
WO/2018/208712A1
The present application discloses stilbene derivative compounds and phenyl- benzofuran compositions, useful in the manufacture of dye-sensitized solar cells and other similar technology.  
WO/2018/203171A1
An organic compound has a benzonaphthofuran skeleton and is represented by Formula (G1). In Formula (G1), A represents a pyrene skeleton. In the case where the pyrene skeleton has a substituent, the substituent is a diarylamino group inc...  
WO/2018/202681A1
The invention is in the technical field of insect control and relates to the use of a disubstituted benzenes for controlling insecticide-resistant pests such as mosquitoes and cockroaches.  
WO/2018/203564A1
Provided is an inhibitor of at least one type of kinase selected from the group consisting of CDK7, CDK4, CDK6, PIM2、TSSK3, MST4, NEK6, MAP3K, MST3, DDR1, SPHK1, CaMK1, AurA, BRK, CaMK4, and PIM1, the inhibitor containing, as an active...  
WO/2018/202525A1
The invention is in the technical field of insect control and relates to novel phenoxyethanamine derivatives, their production and use for controlling pests and in particular insecticide-resistant pests such as mosquitoes and cockroaches.  
WO/2018/198975A1
Provided is a light-emitting element having excellent luminance life. Disclosed is a light-emitting element comprising a positive electrode, a negative electrode, a first organic layer provided between the positive electrode and the nega...  
WO/2018/199466A1
The present invention provides a novel compound and an organic light-emitting element including same.  
WO/2018/198974A1
Provided is a light-emitting element having excellent luminance life. This light-emitting element comprises: a positive electrode; a negative electrode; and a first organic layer and a second organic layer provided between the positive e...  
WO/2018/195439A3
Provided herein, inter alia, are methods and compounds for modulating K-Ras treating cancer.  
WO/2018/195439A2
Provided herein, inter alia, are methods and compounds for modulating K-Ras treating cancer.  
WO/2018/189683A1
The present invention refers to benzofuran derivatives, capable of efficaciously activating the enzymatic complex AMPK, useful for the prophylaxis and therapeutic treatment of diseases and disorders in particular metabolic disorders such...  
WO/2018/190682A1
The present invention provides a novel heterocyclic compound and an organic light emitting device using the same.  
WO/2018/189060A1
The invention comprises novel chiral metal complex compounds of the formula (I) wherein M, PR2, R3 and R4 are outlined in the description, its stereoisomers, in the form as a neutral complex or a complex cation with a suitable counter io...  
WO/2018/190294A1
The present invention mainly addresses the problem of providing a novel medicinal composition which comprises escitalopram as an active ingredient and has secured stability (light stability and heat stability) as a medicine. The present ...  
WO/2018/190516A1
The present invention provides a novel heterocyclic compound and an organic light-emitting element utilizing same.  
WO/2018/188763A1
The present invention concerns a process for the preparation of firocoxib, i.e. 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylpheny l)-furan-2-one, comprising steps (a)-(g), wherein the process provides for step (d) of the react...  
WO/2018/188795A1
The present invention relates to sulfonamide-, sulfinamide- or sulfonimidamide containing compounds which bind to the liver X receptor (LXRa and/or LXRß) and act preferably as inverse agonists of LXR.  
WO/2018/183523A1
An enhanced pyrotechnic composition including an obscurant, a fuel, an oxidizer, and a nonivamide-cyclic anhydride adduct.  
WO/2018/178304A1
Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.  
WO/2018/176803A1
A hydrophobic palladium/metal organic frame material, which is a solid catalyst material obtained by using a porous metal organic frame as a carrier, introducing elemental palladium by means of an imersion-reduction method, and then perf...  
WO/2018/176133A1
The present invention relates to the preparation of compounds of Formula I, including thapsigargin, nortrilobolide and 8-O-debutanoyl-thapsigargin from commercially available (R)-(-)-carvone via synthetic intermediate compound of formula...  
WO/2018/177301A1
The present invention relates to the technical field of medicine, and relates to a 15-idene-14-deoxy-11,12-dehydroandrographolide derivative and a use thereof in anti-fibrosis. Experiments show that this compound can significantly inhibi...  
WO/2018/171817A1
Provided is a miticide composition containing two active ingredients, the first whereof comprising at least one compound selected among the compounds A-7, A-8 and A-10, and the second whereof being a group selected among the first to the...  
WO/2018/171589A1
The present invention belongs to the field of medicine. Provided are citalopram pamoate, a crystal form thereof, and a preparation method and use of the same. The citalopram pamoate has the structure shown in formula I. The citalopram pa...  
WO/2018/172852A1
The present invention includes novel substituted bicyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and co...  
WO/2018/172423A1
The invention relates to a compound which is an indane derivative according to Formula (I), or a pharmaceutically acceptable salt thereof, [FORMULA (I)] wherein R1, R2, R3, n, R4, p¸ q, L, ׇ, X and m are as defined herein. The compound...  
WO/2018/174293A1
An organic electroluminescence element comprising, in the stated order, an anode, an organic layer, a light-emitting layer, and a cathode, the organic layer including the compound represented in formula (20), and the light-emitting layer...  
WO/2018/170932A1
The invention provides a method for preparing 1,5-pentanediol via hydrogenolysis of tetrahydrofurfuryl alcohol. The catalyst used in the method is prepared from a nitrogen-containing ligand functionalized organic polymer or inorganic hyb...  
WO/2018/173500A1
Provided are: an active ester composition having high curability and exceptional properties such as dielectric properties, heat resistance, and moisture absorption resistance in the cured product; a cured product of the composition; and ...  
WO/2018/175190A1
Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.  

Matches 1 - 50 out of 32,233