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Matches 1 - 50 out of 8,050

Document Document Title
WO/2021/052271A1
A magnolol derivative and a preparation method therefor and an application thereof. The magnolol derivative has a structure represented by formula (1). The magnolol derivative has good water solubility, is colorless and transparent after...  
WO/2021/052270A1
The present invention relates to the field of honokiol derivatives. Disclosed are a honokiol derivative, a preparation method therefor and the use thereof, wherein the derivative has a structure as shown in formula (I). The honokiol deri...  
WO/2021/050538A1
This document provides methods and materials for increasing the level of phosphorylated AMPK. For example, compounds (e.g., organic compounds) having the ability to increase the level of phosphorylated AMPK within cells, formulations con...  
WO/2021/047490A1
Disclosed in the present invention is a method for preparing dexibuprofen, comprising: (1) after adding toluene into a reaction kettle, adding ibuprofen and n-octyl-d-glucamine, heating to 76 to 80°C, keeping the temperature and reactin...  
WO/2021/039843A1
The present invention addresses the problem of providing: a (poly)amine compound which is particularly useful as a material for forming a film for lithography or as a material for forming an optical component; a resin which is obtained u...  
WO/2021/039023A1
The present invention provides, inter alia, a novel method for producing a compound represented by formula (I) and a novel method for producing a compound represented by formula (B) or a salt thereof, which are intermediates in the produ...  
WO/2021/024271A1
A continuous process(200) for manufacture of dl-2-nitro-1-butanol from 1-nitropropane is disclosed. The process mixes aqueous solution of sodium hydroxide (A) and a solution of 1-nitropropane (B) dissolved in alcohol(203) at a first mola...  
WO/2021/003462A1
The present invention relates to novel cationic lipids of formula I, and more specifically formula IV. These are used, for example, in liposomes for the delivery of nucleic acids to cells.  
WO/2020/263994A1
The present invention discloses a liquid, propellant-free pharmaceutical formulation and a method for administering a pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler. The propellant-free pharmaceutic...  
WO/2020/257940A1
The present application provides furosemide analogues of the general formula Z having activity as anti-Aβ aggregation agents and/or as inhibitors of Aβ induced neuroinflammation. Formula Z These compounds are useful in preventing, dela...  
WO/2020/249427A1
A process for the conversion of glycolaldehyde with an aminating agent in the presence of hy-5 drogen and of a catalyst, wherein the conversion is carried out in the gas phase.  
WO/2020/248127A1
A borohydride reduction stabilizing system and a method for reducing an ester to an alcohol. The borohydride reduction stabilizing system comprises: a borohydride reducing agent and a stabilizing agent for stabilizing the borohydride red...  
WO/2020/249428A1
A process for the manufacture of ethyleneamines and ethanolamines, comprising the steps of (i) converting a glycolaldehyde derivative of formula (II), in which R2, R3 are - the same or different -hydrogen, alkyl, such as C1-6-alkyl, or c...  
WO/2020/249426A1
A process for the conversion of glycolaldehyde with an aminating agent in the presence of hy- drogen and of a catalyst in a glycolaldehyde conversion reactor, wherein one or more organic carboxylic acids are fed into the glycolaldehyde c...  
WO/2020/238753A1
A preparation method for salicylamine acetate, comprising preparing an amino-protected intermediate from salicylaldehyde, and reacting the intermediate with acetic acid to prepare an acetate.  
WO/2020/223224A1
Described are compounds, compositions, and methods that include a nitrogen- and oxygen-containing aromatic compound, such as an aminophenol-based compound, which can be used for inhibiting polymerization of a monomer (e.g., styrene) comp...  
WO/2020/215895A1
The present invention relates to the technical field of medicine, and relates to derivatives represented by formula 1 and formula 2 in which a carboxylic acid group is introduced into the structure of ginkgolide B by means of a hydroxyl ...  
WO/2020/212157A1
The invention concerns a new, efficient process for the preparation of enantiomerically pure norepinephrine (also known as noradrenaline), or an addition salt thereof, using a catalytic hydrogenation system under hydrogen donor transfer....  
WO/2020/214692A1
Tertiary amine and quaternary ammonium compounds of Formula I and/or Formula II are provided. The present technology also provides compositions that include one or more of the compounds that may be useful for electronics processing (e.g....  
WO/2020/198899A1
A multifunctional, highly active cationic gemini surfactant and a method for producing the same. The present invention uses a protonic acid, epichlorohydrin, and an organic amine as main raw materials to prepare a series of multifunction...  
WO/2020/084599A4
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/178085A1
The present invention relates to a process for preparing alkanolamines and ethyleneamines in the liquid phase, by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst which is obtained by...  
WO/2020/172075A1
Disclosed herein are novel solid forms of FXR agonist of Formula (I). The disclosure also relates to pharmaceutical compositions containing one or more of the solid forms disclosed herein, as well as methods of using the solid forms in t...  
WO/2020/165338A1
The invention pertains to a process for manufacturing ethyleneamine compounds selected from the group of ethyleneamines and hydroxyethylethyleneamines wherein the process comprises two reaction sequences, the first reaction sequence comp...  
WO/2020/165330A1
Process for manufacturing ethyleneamine compounds selected from the group of ethyleneamines and hydroxyethylethyleneamines wherein the process comprises two reaction sequences, the first reaction sequence comprising the steps of: - in an...  
WO/2020/162408A1
The present invention has the effect of making it possible to produce 1,1,1-trifluoro-2,2-bisarylethane efficiently by a simple procedure by condensing a mixture of fluoral and hydrogen fluoride with an aryl compound under anhydrous cond...  
WO/2020/156522A1
Provided are a dezocine derivative of formula I or a tautomer, optical isomer, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof, and a pharmaceutical composition comprising the same, a preparation method therefor,...  
WO/2020/154731A1
Novel salicylamine derivatives are targeted directly to the mitochondria to increase effectiveness and lower required dosages in the treatment of conditions caused by inflammation or oxidative stress.  
WO/2020/153005A1
A composite amine absorption solution according to the present invention is an absorption solution capable of absorbing CO2 or H2S or both of them in a gas, and is prepared by dissolving (1) a linear monoamine, (2) a diamine and (3) a co...  
WO/2020/147160A1
The present invention belongs to the technical field of pharmaceutical chemistry, and specifically relates to a method for preparing fosfomycin trometamol, the method comprising the following steps: 1) adding fosfomycin diamino butantrio...  
WO/2020/084599A3
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/089942A3
A liquid injectable composition comprising (a) at least one surfactant; (b) at least one gel strength enhancer; (c) at least one solvent; (d) optionally release retarding agent(s); (e) optionally stabilizing agent(s); (f) optionally phar...  
WO/2020/132819A1
Disclosed is a method for preparing (1R,3S)-3-aminocyclopentanol hydrochloride. The method comprises using amide formed by chiral carboxylic acid and hydroxylamine as a chiral source, quickly obtaining a chiral Diels-Alder reaction produ...  
WO/2020/120637A1
The application relates to a compound of formula (I) or a pharmaceutical salt thereof of formula (II), as well as to a process to obtain said compound and a process to obtain said salt. Additionally disclosed is the compound of formula (...  
WO/2020/118307A1
This disclosure provides compositions of SALTAME core containing compounds and associated methods for use in tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related me...  
WO/2020/107913A1
The present invention discloses a compound shown in a formula I or a salt thereof, wherein R1 is selected from hydrogen, hydroxyl, C1-6 alkyl, substituted C1-6 alkyl, halogen, amino and thiol wherein the substituted C1-6 alkyl group is s...  
WO/2020/106903A1
The compounds disclosed herein compound of Formula (I), substructures thereof, and pharmaceutically acceptable salts thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a...  
WO/2020/093657A1
Disclosed is a method for preparing 4,6-diamino resorcinol hydrochloride, which belongs to the organic chemical synthesis field. The method comprises: using a Bronsted acid and acetic anhydride as a new dioxime Beckmann rearrangement rea...  
WO/2020/089934A1
This invention relates to methods for racemization of dextro-rotatory ephedrine via enzymatic kinetic conversion, and is particularly useful for conversion of dextro- rotatory ephedrine (d- ephedrine) to racemic mixture of dextro-rotator...  
WO/2020/084599A2
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/071935A1
The present invention relates to choline salts of fumaric acid for use as ingredients in dietary supplements, in medical nutrition, and in pharmaceutical compositions for the prevention and treatment of diseases caused by hypoxia.  
WO/2020/055507A1
Aprotic-protic ionic salt (APS) compositions and methods of using aprotic-protic ionic salt compositions to stabilize nucleic acids at ambient temperatures are provided. Certain aspects provide aprotic-protic ionic salt compositions for ...  
WO/2020/046515A1
The present disclosure provides a quaternary ammonium hydroxide solution comprising a reaction product of a polyamine and an organic oxirane. The quaternary ammonium hydroxide solution may be used in various applications, such as in remo...  
WO/2020/047035A1
The present disclosure provides, inter alia, methods of treating cancer by administering an effective amount of a compound of Formula (I). In some embodiments, the cancer is a solid cancer. In some embodiments, the cancer is melanoma. In...  
WO/2020/042841A1
A preparation method for (1R,3S)-3-amino-1-cyclopentanol and salts thereof, relating to the field of organic synthesis, wherein the (1R,3S)-3-amino-1-cyclopentanol undergoes an asymmetric cycloaddition reaction with cyclopentadiene by us...  
WO/2020/032080A1
Provided is a compound represented by general formula (I), or a salt thereof. (In the formula, X1, X2, X3 and X4 are a hydrogen atom, a C1-9 alkyl group, or a C3-9 unsaturated hydrocarbon group which has 1-4 triple bonds between carbon a...  
WO/2020/029846A1
Disclosed by the present invention is a rapid synthesis method for a biomass-based amine compound, comprising: by using formamide as an amine source, using formic acid as a hydrogen source, and using biomass aldehydes and ketones as raw ...  
WO/2020/028322A1
Improvements in catalyst systems and associated processes for the conversion of glycolaldehyde to monoethanolamine are disclosed. The catalyst systems exhibit improved selectivity to this desired product and consequently reduced selectiv...  
WO/2020/025444A1
Object of the present invention is a better crystalline form of Eltrombopag (ETP) monoethanolamine salt, named Form D, stable, suitable for pharmaceutical purposes, and with the highest solubility in water and excellent non-hygroscopicit...  
WO/2020/025789A1
The present invention relates to salts of elafibranor.  

Matches 1 - 50 out of 8,050