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JP4108743B2 |
PCT No. PCT/EP95/01581 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30648 PCT Pub. Date Nov. 16, 1995Preparation of mixtures of O-phenoxyalkylhydroxylamines Ia and Ib (Ia): H2NOCH2CH(...
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JP4104145B2 |
A stabilized hydroxylamine solution is disclosed. The stabilized solution comprises a selected stabilizer, which can be added during manufacture and/or storage of the hydroxylamine solution.
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JP4093612B2 |
A method for preparing N,N-disubstituted hydroxylamine compounds represented by the formula (II): HO-N(R1)(R2) wherein R1 and R2 may be the same or different, and independently represent a substituted or unsubstituted alkyl group, a subs...
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JP2008513429A |
Compounds of formula (IIa): are provided where: X is a group capable of being cleaved from the alpha -carbon atom to form an ion of formula (I') C Ð is a carbon atom bearing a single positive charge or a single negative charge; The ...
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JP4070407B2 |
This invention is directed to a process for preparing ±,²-unsaturated alkenoate resin compounds.
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JP2008069158A |
To provide an effective terminal differentiation inducer comprising a pharmacologically acceptable carrier and a therapeutically acceptable amount of the compound described below, and a method of using the same.The novel and active termi...
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JP2008069163A |
To provide a method for synthesizing each of aldehydes, ketones, oximes, amines and hydroxamic acid compounds.Provided is a solid-phase synthesis method for each of aldehydes, ketones, oximes, amines and hydroxamic acid compounds. A poly...
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JP4062369B2 |
An integrated process for the preparation of O-substituted hydroxyammonium salts of formula (I) without isolation of intermediates comprises: (a) reacting acetone with hydroxylammonium sulphate and sodium hydroxide solution to give aceto...
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JP2008505879A |
Disclosed are materials and methods for preparing optically active beta-amino acids of Formula 1, which bind to the alpha-2-delta (alpha2delta) subunit of a calcium channel.
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JPWO2005095331A1 |
General formula (I): XYZ (I) [In the formula, X is H2N- or HS-; Y is -A1-, -A1-OA2-,-(CH2CH2O)n-A1-,-(CH2CH2O)n-A1-OA2-, -A1-NH-C (= O) -A2-, -A1-C (= O) -NH-A2-, -A1-(CH2CH2O)n-NH-C (= O) -A2-, -A1-(CH2CH2O)n-C (= O) -NH-A2-Etc .; and Z...
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JP4001393B2 |
The invention provides compounds of the formula: wherein R, R<1>, R<2> and W are defined in the specification. These compounds are useful as antibiotic agents.
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JP2007529467A |
A process for the preparation of a sterically hindered amine ether which comprises reacting a corresponding sterically hindered aminoxide with a C5-C18alk-1-ene in the presence of an organic hydroperoxide and optionally hydrogenating the...
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JPWO2005075639A1 |
To provide a method for producing a glycopeptide in which a sugar chain can be easily introduced. In the present invention, an amino acid having a protected group for introducing a sugar chain is introduced into a protein by a 4-base cod...
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JP2007528404A |
The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of d...
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JP2007254426A |
To provide an arylamine derivative having excellent solubility in a solvent and compatibility with a binder resin, exhibiting good sensitivity, and capable of maintaining a prescribed sensitivity over a long time; and to provide a method...
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JP2003518475A5 |
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JP2007523087A |
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
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JP3955180B2 |
The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, ...
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JP3950046B2 |
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.
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JPWO2005061444A1 |
A fullerene derivative containing a site capable of specifically binding a sugar chain and a fullerene nucleus regardless of the type of sugar chain is provided, and only the signal of the sugar chain is significantly shifted from the mo...
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JP3935199B2 |
The present invention relates to novel 5-HT4 receptor ligands which are 1-(5-halo-4-aminophenyl) (C2-6)alkan-1-one derivatives in which the 5-halo-4-aminophenyl group is substituted at its 2-position with (C1-4)alkyloxy or phenyl(C1-4)al...
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JP3927772B2 |
The present invention relates to the use of certain resorcinol derivatives as skin lightening agents.
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JP3924124B2 |
The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, ...
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JP2007126460A |
To provide a compound and a composition effective for inhibiting the activity of a CETP [cholesterol ester transfer protein (plasma lipid transfer protein-1)] and useful for treating especially atherosclerosis and other coronary arterial...
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JP2007513098A |
The invention relates to compounds of general formula I wherein D, E, F, G, W, Y, R1, A, R9, X, B, R8 are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one...
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JP3914065B2 |
To provide a new compound that inhibits retrovirus proteases, especially proteases of human immunodeficiency virus(HIV), a composition for treating retrovirus infection, especially for treating HIV infection, a production method of the c...
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JP2007112804A |
To provide substituted aryl and heteroaryl (R)-chiral halogenated 1-substituted amino-(n+1)-alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and a composition of the com...
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JP2007509842A |
Compounds comprising nitric oxide derivatives of stilbenes, polyphenols and flavonoids and methods of their use are provided for treating patients suffering from any of hypercholesterolemia, vascular oxidative stress and endothelial dysf...
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JP2007077170A |
To provide a technique of a simple and inexpensive system by which activators in a wide range can be delivered and which can be prepared easily.The modified amino acid compound useful in the delivery of an active agent is provided. The a...
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JP2007077038A |
To facilitate the control of a reaction system in the production of a crystalline N-nitroso-N-phenylhydroxylamine aluminum salt and solve various problems on environment and working hygiene.The production method comprises the first step ...
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JP3883566B2 |
Carbamates of the formula I wherein B is a saturated or unsaturated heterocyclic group, and the other substituents are defined in the specification, and having crop protection properties.
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JP2007501802A |
Compositions and methods of using compositions for treatment of inflammatory diseases and immune disorders are provided. Allylhydrazine compounds, hydroxylamine (aminooxy) compounds, and other compounds are disclosed which are inhibitors...
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JP3863178B2 |
The present invention provides aromatic amine substituted metal chelating compounds of formula (I) in which the variables are as defined in the claims, chelates and chelate-targeting moiety conjugates formed from the chelating compounds,...
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JP3863694B2 |
To provide a method for preventing the N-oxyl compound in vinyl compounds from reducing with the passage of time. The N-oxyl compound is characteristically stabilized in vinyl compounds by adding the N-oxyl compound together with N-hydro...
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JP3838659B2 |
2-[(Dihydro)pyrazol-3'-yloxymethylene]anilides of the formula I processes and intermediates for their preparation and their use as pesticides and fungicides.
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JP3827017B2 |
A process and catalyst composition are provided for the highly efficient enantioselective hydrogenation of dehydroamino acid derivatives. The catalyst composition comprises rhodium or iridium and a diphosphinite carbohydrate ligand, wher...
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JP3821863B2 |
PURPOSE: To obtain a new hydroxylamine compound useful as a reagent to obtain protected hydroxamic acid derivatives. CONSTITUTION: The compound of formula I (R is 2-pyridyl or a 2trialkylsilyl), e.g. o-[2-(2-pyridyl)ethyl]hydroxylamine. ...
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JP2006232695A |
To provide a new compound that is produced by actinomyces and provide a method for producing the new compound.This invention is a compound represented by formula (1) (wherein X is H atom, carboxy or a 1-20C alkyl, Y is a monovalent subst...
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JP2006232845A |
To provide an HIV protease inhibitor useful for treating or preventing AIDS.The retroviral protease-inhibiting compound is represented by general formula (A). Preferably, in the formula, R1 is a thiazolyl or oxazolyl which may be substit...
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JP2006519786A |
Improved processes for preparing intermediates useful for preparing antibacterial N-[1-oxo2-alkyl-3-(N-hydroxyformamido)-propyl}-(carbonylamin
o-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, which have one or more of ...
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JP3812969B2 |
To obtain the subject new compound having a specific molecular structure, exhibiting an action on the inhibition of a retrovirus protease, and useful for the therapy of retrovirus infection, especially human immunodeficiency virus(HIV) i...
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JP3806304B2 |
According to the inventive method for producing organic hydroxylamines, at least one organic nitro compound is partially hydrogenated in the presence of an organic base or ammonia, a trivalent phosphor compound and a hydrogenation cataly...
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JP2006516620A |
Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases ...
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JP3789929B2 |
PCT No. PCT/DE93/00117 Sec. 371 Date Aug. 11, 1994 Sec. 102(e) Date Aug. 11, 1994 PCT Filed Feb. 8, 1993 PCT Pub. No. WO93/16124 PCT Pub. Date Aug. 19, 1993Diaminocarbonate compounds are disclosed which are particularly suitable as low-o...
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JP3778567B2 |
PCT No. PCT/EP96/00170 Sec. 371 Date Jul. 7, 1997 Sec. 102(e) Date Jul. 7, 1997 PCT Filed Jan. 17, 1996 PCT Pub. No. WO96/22967 PCT Pub. Date Aug. 1, 1996A process for preparing aromatic or heteroaromatic hydroxylamines of the general fo...
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JP3776153B2 |
To obtain a new 1,5-disubstituted 7a-methylperhydroinden-3a-ol having excellent affinity for Na+, K+-APase, useful for treating cardiovascular disorders. This compound is shown by formula I {a broken line is a single bond or a double bon...
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JPWO2004058687A1 |
The present invention provides a substance capable of specifically interacting with a sugar chain. Furthermore, the present invention is a method for separating, concentrating or purifying a sugar chain or a sugar chain-containing substa...
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JP2006513152A |
Disclosed are taxanes having utility as intermediates in the preparation of paclitaxel, taxotere and analogs thereof, and methods related to the preparation of the same.
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JP2006512280A |
Disclosed is a compound having the formula: pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solva...
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JP2006511564A |
The present invention relates to compounds of the general formula (II) and salts and physiologically functional derivatives thereof, for the use as a medicament.
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