Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 101 - 150 out of 6,862

Document Document Title
WO/2020/225273A1
Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment dis...  
WO/2020/222103A1
The present invention relates to elastomer compositions comprising adducts between compounds of formula (I) preferably derived from natural sources such as mucic, pyromucic, glucaric, glycaric, galactaric, muconic acid and/or linear deri...  
WO/2020/222010A1
The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: (I) wherein R A, R B, R C and R D are as defined herein.  
WO/2020/212543A1
The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive unit, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalm...  
WO/2020/214901A1
Compositions and methods for protecting an organism from a pathogen are disclosed.  
WO/2020/209035A1
A compound represented by formula (1). R1 is, for example, an alkyl having 1-15 carbon atoms; ring A1 and ring A2 are 1,4-phenylene, etc.; a is 2, etc.; b and c are 0, 1, or 2; Z1 is a single bond, etc.; P1 and P2 are polymerizable group...  
WO/2020/210486A1
The disclosure provides processes for preparing α-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxami de, as well as intermediates for use in said processes.  
WO/2020/187150A1
Disclosed are new crystal forms of dapagliflozin and a preparation method thereof. Particularly, the X-ray powder diffraction pattern of the crystal form A of dapagliflozin has characteristic diffraction peaks at the following 2θ angles...  
WO/2020/184142A1
[Problem] To provide a compound which has high stability with respect to heat, high voltage holding ratio if used in a liquid crystal display element, and the like. [Solution] A compound which is represented by formula (1). In the formul...  
WO/2020/183422A1
This disclosure relates to use of cashew nut shell liquid (CNSL) phenolics in the manufacture of molecules having ESIPT character, wherein said molecules are UVA and/or UVB absorbers, and further wherein said molecules are formulated as ...  
WO/2020/171507A1
The present invention provides: novel compounds capable of producing monomethyl fumarate after administration; pharmaceutical compositions comprising same as active ingredients; and pharmaceutical uses thereof for treatment or alleviatio...  
WO/2020/165882A2
The present invention relates to a method of producing high-purity 2-pyrone-4,6-dicarboxylic acid (PDC), and a method of producing an intermediate for same, the methods comprising the steps of: 1) producing terephthalic acid (TPA) from P...  
WO/2020/151620A1
Disclosed are a compound as represented by formula II, and an isomer or available salt thereof. Also disclosed specifically are a manufacturing method for the compound, and the isomer or available salt thereof, and an application of the ...  
WO/2020/151672A1
Provided are a new crystal form of dapagliflozin and a preparation method therefor, a pharmaceutical composition comprising the crystal form, and a use of the crystal form in preparation of a sodium-glucose cotransporter inhibitor and a ...  
WO/2020/151623A1
The present invention pertains to the medical field and relates to a compound of formula (III), a stereoisomer or pharmaceutically acceptable salt thereof. The present invention also relates to a method for preparing the compound, a ster...  
WO/2020/151621A1
The present invention belongs to the field of medicine, and specifically relates to a compound of formula (I), an isomer or a pharmaceutical salt thereof. This present invention more specifically relates to a compound, a stereoisomer the...  
WO/2020/144297A1
The present invention concerns nanoemulsions encapsulating a prodrug and bearing a targeting ligand, said nanoemulsion being formed by a natural oil and/or a synthetic oil and an amphiphilic surfactant, the methods for preparing these na...  
WO/2020/132820A1
Disclosed is a synthesis method for 3-(benzyloxy)-4-oxo-4H-pyran-2-carboxylic acid. The acid takes furfuryl alcohol as a starting material and is prepared with four steps: rearrangement, addition, hydroxyl protection and oxidation.  
WO/2020/129900A1
The purpose of the present invention is to provide a method for industrially and efficiently producing a C-arylhydroxy glycoxide derivative at low cost. The present invention provides a method for producing a C-arylhydroxy glucoxide deri...  
WO/2020/129899A1
In order to provide a method for the economical and efficient industrial production of C-aryl hydroxy glycoxide derivatives, the present invention provides a method for producing a C-aryl hydroxy glycoxide derivative represented by formu...  
WO/2020/120528A1
The present invention provides the compounds having the general formula: (I) wherein R1 to R8, and X are as described herein, compositions including the compounds and methods of using the compounds.  
WO/2020/120141A1
A series of functionalised amine derivatives of formula (I) as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammato...  
WO/2020/120643A1
The present invention is concerned with fragrance ingredients and with fragrance preparations, for imparting desirable odor notes to consumer products, in particular it is concerned with (2S,4R)-4-methyl-2-((Z)-2-methylbut-1-en-1-yl)tetr...  
WO/2020/116555A1
The present invention addresses the problem of providing: a liquid crystal composition which contains a polymerizable compound and which is used for producing a PSA type or PSVA type liquid crystal display element, wherein the speed of p...  
WO/2020/107124A1
The present invention provides a method of modulating leukocytes activation (e.g., adhesion and/or transmigration and/or cytokine response) and a method of modulating thrombocyte clearance comprising administering to a subject in need th...  
WO/2020/105061A1
This invention is related to an improvement in the process of filtrate extension of a reaction where at least a set of filtrates of a set of reaction are mixed together to form for a filtrate extension thereby the reaction yields higher ...  
WO/2020/089134A1
The invention relates to a process for preparing 2-substituted 4-methyl-tetrahydropyrans from 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans as starting materials.  
WO/2020/084559A1
The present invention is directed to glucopyranose derivatives of formula (I), pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by SGLT2 activity. More particularly, the com...  
WO/2020/086691A1
This current disclosure is directed to charge-transfer heptamethine dyes for NIR singlet oxygen generation, each such dye comprising a near-infrared (NIR) absorbing dye having heptamethine linkages orthogonally coupled to an optionally s...  
WO/2020/084560A1
The present invention is directed to glucopyranose derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by SGLT2 activity. More particularly, the compounds of the p...  
WO/2020/079052A1
The present invention refers to dihydropyran derivatives, and to a process of making the same. The invention further refers to perfume compositions and fragranced articles comprising them.  
WO/2020/076920A1
The present disclosure provides compositions and methods for metathesizing a first alkenyl or alkynyl group with a second alkenyl or alkynyl group, the composition comprising a ruthenium metathesis catalyst and a photoredox catalyst that...  
WO/2020/071550A1
The present invention provides a novel CDK8 inhibitor. The present invention relates to: a compound represented by general formula (I) (wherein the symbols are as defined in the description) or a pharmaceutically acceptable salt thereof;...  
WO/2020/067457A1
The objective of the present invention is to provide a compound which may be useful for preventing or treating constipation or the like. The present invention provides a compound represented by formula (I) [each symbol in the formula is ...  
WO/2020/068661A1
Methods of preparing, and solid forms of N-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2- yl)-4-(4-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(m ethylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)butanamide, and salts, s...  
WO/2020/059790A1
The the present invention addresses the problem of providing a DP receptor antagonist. Compounds represented by general formula (I): (in the formula, all of the symbols are as defined in the specification) and pharmacologically acceptabl...  
WO/2020/056553A1
The invention belongs to the field of organic chemistry, and particularly relates to a method for preparing a heterocyclic compound represented by formula I and salts thereof. Compared with the prior art, the invention avoids the use of ...  
WO/2020/054226A1
A thermal base generator is represented by formula (N1). This photosensitive resin composition contains the thermal base generator and a precursor of a heterocycle-containing polymer. In formula (N1), RN1 and RN2 each independently repre...  
WO/2020/050361A1
The purpose of the present invention is to provide a method for quickly reducing a C-aryl-hydroxy glycoside derivative that is represented by formula (2) at a low temperature and highly selectively producing a β-C-aryl glycoside derivat...  
WO/2020/039092A2
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/039094A1
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/039088A2
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/035782A1
The present invention relates to compounds according to structure (I) whereby one of R1 to R3 is -OCOCD3 and the other two are either hydroxyl or OAc, their synthesis and their use in for the analysis of the metabolism of glycolysis inhi...  
WO/2020/029114A1
Disclosed is a production process for preparing high-purity dehydroacetic acid by using melt crystallization, the process including the following steps: first introducing chilled brine into the bottom of a jacket on the outside of a melt...  
WO/2020/023323A1
Disclosed herein is a small molecule targeted drug conjugate for anti-influenza chemotherapy and immunotherapy. The disclosed drug conjugate may form an adaptor to recruit additional CAR T cells or other immune cells for precise eliminat...  
WO/2020/023368A1
Described are novel derivatives of pogostone of formula (I) and methods of using the same.  
WO/2020/021113A1
The invention relates to a process to prepare a compound of the following formula (I): (I), in which P represents a protective group of a hydroxyl function which is a -COR1 group with R1 representing an aryl or a (C1C6)alkyl, R represent...  
WO/2020/015343A1
The present invention provides compounds of Formula (I) which can be used as ACC inhibitors and potently as therapeutic agents against diseases mediated by ACC.  
WO/2020/012336A1
Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment di...  
WO/2019/204753A9
A method of making of 1,2,5,6-hexanetetrol ("tetrol"). The method includes the steps of contacting a reaction solution containing water as well as levoglucosenone, dihydrolevoglucosenone, and/or levoglucosanol, with a catalyst ontaining ...  

Matches 101 - 150 out of 6,862