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Matches 1 - 50 out of 5,380

Document Document Title
WO/2022/170122A1
The present disclosure relates compounds of Formula (I'): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparing the compounds, compositions comprising the compounds, ...  
WO/2022/167445A1
The present invention provides compounds of formula I, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.  
WO/2022/167631A1
The invention provides novel heteroaryl-substituted imidazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1 to R6 are as described herein. Further provided are pharmaceutical ...  
WO/2022/162471A1
Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.  
WO/2022/161496A1
The present disclosure provides compounds having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein variables are as defined as set forth in the specification. The present disclosure also provides compound...  
WO/2022/158442A1
The present invention provides, as a radioactive halogen-labeled precursor compound that is highly stable and reactive, a compound represented by general formula (II) [in the formula, R1 and R2 each independently represent an alkyl group...  
WO/2022/157499A1
The invention relates to protected HDAC inhibitor compounds of formula I, in which Y, Ar1, Ar2, X, R1 and R2 are as defined herein. In aspects, the inventions relates to use of the compounds, and to methods of deprotecting the compounds.  
WO/2022/150174A1
The present invention provides for compounds of Formula (I) (I) wherein R1 has any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of...  
WO/2022/148717A1
The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing these compounds.  
WO/2022/139179A1
The present invention provides a heterocyclic compound represented by chemical formula 1 and an organic light-emitting device comprising same.  
WO/2022/138735A1
Although compounds for treating or ameliorating malignant diseases have been proposed, patients had to endure a large burden since many of such compounds could not be orally ingested. Mangiferin has an effect of ameliorating malignant di...  
WO/2022/138987A1
The present invention provides a compound exhibiting a coronavirus 3CL protease inhibitory effect and pharmaceutically acceptable salts thereof, and a pharmaceutical composition containing the same. Further provided are crystals that are...  
WO/2022/135136A1
Provided herein are tuberculatin analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.  
WO/2022/133027A1
Compounds of formula (1) wherein R1 represents a -C(R2)(R3)-[C(R4)(R5)]m-L-R6 group or -R7; and the preparation and the therapeutic uses of the compounds of formula (1) as agonists of TRPM8 receptors, useful especially in the treatment o...  
WO/2022/131546A1
The present specification relates to a heterocyclic compound represented by chemical formula 1, an organic light-emitting device comprising same, a manufacturing method therefor, and a composition for an organic layer.  
WO/2022/133031A1
This disclosure relates generally to inhibitors of MHC-I downmodulation, and methods of treating or preventing an HIV infection by administering the inhibitors to a patient in need of treatment thereof.  
WO/2022/124499A1
The present specification pertains to a heterocyclic compound represented by chemical formula 1, and an organic light-emitting device comprising same.  
WO/2022/117445A1
Compounds of Formula (I) wherein the substituents are as defined in claim 1. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling wee...  
WO/2022/112345A1
The invention relates to compounds that are useful for the prevention or treatment of TRPM3 mediated disorders, more in particular disorders selected from pain and inflammatory hypersensitivity. The invention also relates to a method for...  
WO/2022/112352A1
The invention relates to compounds that are useful for the prevention or treatment of TRPM3 mediated disorders, more in particular disorders selected from pain and inflammatory hypersensitivity. The invention also relates to a method for...  
WO/2022/114164A1
Provided is a compound which is useful as an active ingredient for a pharmaceutical composition for treating cancer associated with the activation of an immunocyte or cancer having resistance to an anti-PD-1 antibody/anti-PD-L1 antibody ...  
WO/2022/114444A1
The present invention relates to a novel heterocyclic compound usable in an organic light-emitting device and to an organic light-emitting device comprising same, wherein [chemical formula A] and [chemical formula B] are as described in ...  
WO/2022/108259A1
The present specification provides a compound of formula 1 and an organic light-emitting device comprising same.  
WO/2022/108068A1
The present specification relates to a compound of chemical formula 1 and an organic light-emitting device comprising same.  
WO/2022/107144A1
The present invention is directed to compounds and compositions comprising thereof. Further, methods of use such as for the treatment and prevention of a disorder associated with binding of IGF2BP1 to an RNA in a subject in need thereof ...  
WO/2022/108258A1
The present specification provides a compound of chemical formula 1 and an organic light-emitting device comprising same.  
WO/2022/105845A1
A glucoside derivative, and a preparation method therefor and an application thereof. Specifically, provided is a glucoside derivative, which is a compound as represented by formula (I) or a pharmaceutically acceptable salt thereof. The ...  
WO/2022/106375A1
The present invention provides novel compounds having the general formula (I) wherein A, L, and B are as described herein, compositions including the compounds and methods of using the compounds.  
WO/2022/105852A1
Provided are a triazine dione derivative, a preparation method therefor and an application thereof in medicine. Specifically, provided are a triazine dione derivative represented by general formula (I), a preparation method therefor, a p...  
WO/2022/108141A1
The present specification relates to a compound of chemical formula 1 and an organic light-emitting device comprising same.  
WO/2022/099810A1
A tetraphenylethylene compound, an application thereof, and an electronic device using same. The structural general formula of the tetraphenylethylene compound is shown in formula 1. The tetraphenylethylene compound contains an aromatic ...  
WO/2022/094355A1
The present disclosure relates to a class of pyrimidine compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, stereoisomers, solvates, and hydrates thereof. The present disclosure also relates to a process of prep...  
WO/2022/093748A1
This invention relates to processes for making bio-based renewable oils from non-food biomass sources. Such renewable oils are used for cosmetics formulations. More specifically, disclosed are processes of preparation of furan-based comp...  
WO/2022/094354A1
The present disclosure relates to a class of pyrimidine compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, stereoisomers, solvates, and hydrates thereof. The present disclosure also relates to a process of prep...  
WO/2022/080765A1
The present invention relates to a skin whitening composition comprising a dihydrofuran-2(3H)-one derivative having melanogenesis inhibition and melanosome decomposition activity, an isomer thereof, or a pharmaceutically acceptable salt ...  
WO/2022/073969A1
The present invention relates to compounds of Formula (I), wherein Ar1, A, B, and R1 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceut...  
WO/2022/060020A1
The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device using same and, more specifically, to: a compound having excellent thermal stability, electrochemical stability, light-...  
WO/2022/053628A1
The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the ...  
WO/2022/053013A1
Disclosed in the present invention are a compound represented by formula Ib or IIb, a cis or trans isomer, enantiomer, diastereomer, racemate, tautomer, solvate, hydrate, and pharmaceutically acceptable salt thereof, or a mixture thereof...  
WO/2022/050533A1
The present invention provides a novel compound and an organic light-emitting device using same.  
WO/2022/050592A1
The present specification relates to a heterocyclic compound represented by chemical formula 1, and an organic light-emitting element comprising same.  
WO/2022/047014A1
The present disclosure relates to copper complexes, pharmaceutical compositions comprising these complexes, chemical processes for preparing these complexes, and their use in the treatment of neurodegenerative disease, e.g., amyotrophic ...  
WO/2022/042299A1
A method for extracting mupirocin. The main steps thereof comprise: resin adsorption, desorption and concentration, multi-step extraction, and dehydration and decoloration, wherein the multi-step extraction comprises at least one ester s...  
WO/2022/040788A1
Anti -cancer, chemotherapeutic, or antiproliferative compositions comprising, as an active ingredient, a compound of formula (I0), or a salt, or prodrug thereof: and an anti-cancer, chemotherapeutic, or antiproliferative compound (A) or ...  
WO/2022/045618A1
Provided is a tertiary amine derivative, which effectively absorbs high-energy external light source in a UV region to minimize damage to organic materials inside an organic electroluminescent device, and thus contributes to a substantia...  
WO/2022/034203A1
The present invention provides, inter alia, a process for producing a compound of formula (I) wherein the substituents are as defined in claim 1. The present invention further provides intermediate compounds utilised in said process, and...  
WO/2022/033380A1
The present invention relates to the technical of medicinal chemistry, and specifically relates to a use of a 6-oxaspiro[4.5] decane derivative as an MOR receptor agonist for treating pain and pain-related disorders.  
WO/2022/031735A1
The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods o...  
WO/2022/031736A1
This disclosure is drawn to substituted pyridine compounds and compositions, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing a neurological diseases.  
WO/2022/028507A1
A heterocyclic compound as represented by formula I, a preparation method therefor, a pharmaceutical composition comprising same and use thereof. The heterocyclic compound can be used as a complement factor B inhibitor, and is used for p...  

Matches 1 - 50 out of 5,380