| Document |
Document Title |
|
WO/2024/083491A1 |
The invention relates to an oligosaccharide of formula I derived from rare sugars, wherein R, X and n have the meanings defined in the specification. The invention also relates to its process to obtain it and to its use as a prebiotic an...
|
|
WO/2024/082175A1 |
The present invention provides a preparation method for a sucralose refined product, and relates to the technical field of fine chemical engineering. In the present invention, by means of subjecting a sucralose crude product to ethyl ace...
|
|
WO/2024/082158A1 |
Provided in the present invention is a method for preparing a sucralose crude product by using a sucralose-6-acetate crystallization mother liquor. In the present invention, by using an alkali metal hydroxide for alkaline hydrolysis, suc...
|
|
WO/2024/083746A1 |
The invention pertains to methods for the synthesis of oligonucleotides using pseudo solid-phase protecting groups, wherein said method comprises at least one aqueous extraction carried out in the presence of one or more amide solvents S...
|
|
WO/2024/082156A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
|
|
WO/2024/082154A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
|
|
WO/2024/082157A1 |
The present invention relates to the technical field of fine chemical engineering, and provides a method for preparing a crude sucralose by using an alcohol-water alkaline hydrolysis system. According to the present invention, a sucralos...
|
|
WO/2024/086623A1 |
A method of separating and recovering a first carbohydrate from a feed solution comprising two or more carbohydrates and salts using a chromatography separation system which comprises one or more strong acid cation exchange resin, and re...
|
|
WO/2024/082177A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
|
|
WO/2024/036254A3 |
The present invention relates to a process for producing compounds of formula I and/or formula I'. The present invention also relates to a process of selectively cleaving the main ring of a compound of formula IV to provide the starting ...
|
|
WO/2024/044741A3 |
Described herein are highly pure, chemically synthesized, stabilized, 5'-capped oligonucleotides. Additionally, described herein are methods for making and using said oligonucleotides.
|
|
WO/2024/077410A1 |
The present application relates to the technical field of metal ion chemistry, and provides a method for reducing an azide methoxy group, a sequencing method, and a kit. The method for reducing an azide methoxy group provided by the pres...
|
|
WO/2024/054921A3 |
The present disclosure relates to microorganisms useful in the biosynthesis of psicose. Also provided are methods of producing the disclosed microorganism and methods of producing psicose.
|
|
WO/2024/075760A1 |
The present invention addresses the problem of providing: a novel method for producing a N-acetyl-D-galactosamine ligand-oligonucleotide conjugate, particularly a novel method for producing a N-acetyl-D-galactosamine unit; and a novel in...
|
|
WO/2024/075025A1 |
The present invention relates to an industrial process for the preparation of 2,3-O-Isopropylidene-D-ribofuranose of formula (I). The intermediate of formula (I) is used for the preparation of Varitriol, Carbovir, Abacavir, Sapropterin d...
|
|
WO/2023/280934A9 |
The present invention relates to a 5'-cap analog according to formula (I) or salts thereof, wherein the 5'-cap analog comprises a photocleavable group fused via a carbamate moiety to the 5'-cap structure.
|
|
WO/2024/066250A1 |
The present invention provides an immobilized 4,5-dicyanoimidazole, a preparation method therefor, and use thereof. The immobilized 4,5-dicyanoimidazole is obtained by a free radical copolymerization reaction of a first comonomer, a seco...
|
|
WO/2024/065048A1 |
The present disclosure relates to sweetened fibers, compositions thereof, and products comprising the sweetened fiber of the present disclosure, and uses thereof. The present disclosure also relates to methods of preparing the sweetened ...
|
|
WO/2023/212134A9 |
The disclosure provides methods for synthesis of peracetylgalactosamine-1-pentanoic acid, also called peracetylated D-galactosamine C5 linker or GalNAc C5 linker, using a vegetal source as a starting material, such as vegetal-sourced D-g...
|
|
WO/2024/061842A1 |
A method for the solid-phase synthesis of a target oligonucleotide OT is disclosed, wherein said method comprises a step of incubating a nucleoside or oligonucleotide, which is covalently linked to a solid support and comprises a backbon...
|
|
WO/2024/061271A1 |
Disclosed is a biotinylated heparin pentasaccharide capable of being neutralized, which has a structure as represented by formula (I). The anti-coagulation activity of the biotinylated heparin pentasaccharide capable of being neutralized...
|
|
WO/2024/058256A1 |
Provided is a method for dissolving a polysaccharide such as cellulose under acidic and mild conditions using a solution containing hydrochloric acid and zinc chloride, wherein the hydrogen chloride concentration in the hydrochloric acid...
|
|
WO/2024/055758A1 |
The present invention relates to the technical field of biological medicines. Disclosed are a cyclic dinucleotide metal compound, and a preparation method therefor and a use thereof. The structural formula of the compound is [M(cyclic di...
|
|
WO/2024/059258A1 |
Click-labeled uridine bases, nucleosides, and phosphoramidites are provided, including improved methods of synthesis, oligonucleotides comprising the click-labeled nucleosides, methods of synthesizing spin-labeled oligonucleotides using ...
|
|
WO/2024/053574A1 |
[Problem] The present invention addresses the problem of providing a novel oligosaccharide that is a two-branched glycan that has an α2,6-sialic acid structure at the non-reducing end, a production method for the oligosaccharide, an int...
|
|
WO/2024/051696A1 |
The present invention relates to a compound for RNA capping and use thereof and belongs to the technical field of genetic engineering. The compound has a structure represented by formula I. The compound is used for capping an mRNA5' end,...
|
|
WO/2024/050809A1 |
Provided is a method for the glycosylation modification of proteins and/or polypeptides, belonging to the technical field of medicinal chemistry. Using glycosyl sulfinate as a raw material, a method for the glycosylation modification of ...
|
|
WO/2024/047122A1 |
The invention relates to a process for the preparation of a particulate allulose composition, the process comprising the steps of providing an aqueous allulose syrup; evaporating water from the allulose syrup; adding seed crystals of all...
|
|
WO/2024/046993A1 |
Disclosed is a process for the production of a human milk oligosaccharide (HMO) derived by a microbial fermentation method, the process comprising the steps of: a) providing a fermentation broth comprising at least one HMO and biomass; b...
|
|
WO/2024/047096A1 |
The present invention relates to processes for the purification of an oligosaccharide from a solution, a product of such processes, and the use of a product of such processes.
|
|
WO/2024/049312A2 |
The first object of the invention is a method for the synthesis and purification of a nucleotide and/or a nucleoside. The second object of the invention is a modified nucleoside and/or a nucleotide, being a mono-, di- or triphosphate, co...
|
|
WO/2024/047121A1 |
The invention relates to a process for the preparation of a particulate allulose composition, the process comprising the steps of providing an aqueous allulose syrup; evaporating water from the allulose syrup; allowing the composition to...
|
|
WO/2024/044741A2 |
Described herein are highly pure, chemically synthesized, stabilized, 5'-capped oligonucleotides. Additionally, described herein are methods for making and using said oligonucleotides.
|
|
WO/2024/044792A1 |
Disclosed herein are chemical preparation of oligonucleotides, chemical entities useful in such preparation, processes for such preparation, and methods of use relating to the chemical preparation of oligonucleotides. Further disclosed h...
|
|
WO/2024/036768A1 |
A method for extracting stevioside RD. The method comprises the following steps: providing a solution containing stevioside RD, wherein the pH of the glycoside solution is 5 to 6; at 20-25℃, causing a macroporous neutral adsorption res...
|
|
WO/2024/040091A1 |
Embodiments of the present disclosure relate to lipid-PEGylated solid support and phosphoramidites derivatives, methods for preparing the same, and their uses in the delivery of oligonucleotide drugs to the cellular targets.
|
|
WO/2024/038195A1 |
The present invention relates to new specific 2'-fucosyllactose propionate compounds, to a new and improved synthesis of specific 2'-fucosyllactose propionates as well their use. Propionate compounds are very useful compounds.
|
|
WO/2024/036254A2 |
The present invention relates to a process for producing compounds of formula I and/or formula I'. The present invention also relates to a process of selectively cleaving the main ring of a compound of formula IV to provide the starting ...
|
|
WO/2024/036275A1 |
The present disclosure provides a method of producing cyclic dinucleotides (CDNs) on a commercial scale. Also provided are pharmaceutical compositions comprising a purified CDN preparation and use thereof to stimulate the immune system i...
|
|
WO/2024/022894A1 |
The present disclosure relates to a process for recovery of a nucleic acid product from a composition. The process (100) comprising: (i) contacting (110) the composition with a chromatography material functionalised with a ligand. The ch...
|
|
WO/2024/024760A1 |
The purpose of the present invention is to provide a highly stable pyrazolone compound. This problem can be solved by a pyrazolone compound represented by formula (1) of the present invention (in the formula, R1 is an electron-withdraw...
|
|
WO/2024/019577A1 |
The present invention relates to: a pretreatment process performed at room temperature for the purpose of recovering fermentable sugars from biomass including chestnut shell; and a biorefinery process comprising the pretreatment process,...
|
|
WO/2024/012126A1 |
Disclosed in the present invention is a cordycepin-derivatized compound with an anti-tumor effect, which has a structure as represented by formula I. The cordycepin derivative and a pharmaceutical composition thereof provided in the pres...
|
|
WO/2024/012178A1 |
A method for preventing crystalline maltitol from caking during storage, comprising the following steps: performing online real-time detection on the temperature and humidity of dried crystalline maltitol; separately configuring screenin...
|
|
WO/2024/008701A1 |
The present invention relates to a method of removing calcium citrate from a liquid dairy stream. In particular, the present invention relates to a method of removing calcium citrate from a liquid dairy stream wherein the liquid dairy st...
|
|
WO/2024/005723A1 |
The present invention relates to a novel granulated or powdered brown natural slow sugar and a process for manufacturing the same based on esterification. The product obtained, i.e. the novel brown natural slow sugar, can be consumed by ...
|
|
WO/2024/005722A1 |
The present invention relates to a novel granulated or powdered white natural slow sugar and to a process for manufacturing same based on esterification. The product obtained, i.e. the novel white natural slow sugar, can be consumed by a...
|
|
WO/2024/003840A1 |
The present application relates to a process for producing glucose comprising reacting water and carbon from a carbon source in the presence of a melanin device, which comprises melanin and a substrate material (e.g., silica, plastic, or...
|
|
WO/2023/245821A1 |
Disclosed in the present invention is a preparation method for an N-acetyl-D-galactosamine trimer precursor. With respect to the preparation of the trimer precursor, a preparation method for compound 4 comprises: adding compound 3, a 4Å...
|
|
WO/2023/250513A1 |
Provided are 13-membered macrolides that can be used to treat proliferative diseases such as cancer as well as genetic diseases that are associated with a premature termination codon mutation or other nonsense mutations. The compounds ca...
|
