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Matches 1 - 50 out of 4,763

Document Document Title
WO/2022/168846A1
A barrier function improver which contains methylhesperidin as an active ingredient, and a barrier function improver composition which contains said barrier function improver and a pharmaceutically acceptable carrier.  
WO/2022/151978A1
Provided in the present invention is a pharmaceutically active ingredient extract extracted from Polygala japonica Houtt., which extract comprises a flavonol compound of the following formula (I) structure as a first active ingredient, a...  
WO/2022/134385A1
The present invention relates to the technical field of agricultural chemicals and preparation. Specifically, disclosed is a purification method for 4"-(s)-methylamino abamectin B2a benzoate. The purification method comprises the followi...  
WO/2022/133314A1
Disclosed herein are enzymatic and modified host cell methods for prepared modified indole alkaloids. Also disclosed herein are modified indole alkaloids and their therapeutic use for treating diseases and disorders.  
WO/2022/094694A1
Functional food comprising montbretin A and use of the functional food for limiting polysaccharide processing in a human subject and for treating conditions treatable by inhibiting pancreatic a-amylase.  
WO/2022/089589A1
A flavonoid glycoside-organoamine DPP-4 inhibitor double salt. The flavonoid glycoside has the structural formula as shown in formula (1), wherein R1-R9 are independently selected from a group consisting of -H, -OH, C1-C6 alkyl, alkoxy o...  
WO/2022/089590A1
The present application relates to a complex salt compound of a flavonoid glycoside and an organic amine tyrosine kinase inhibitor. The flavonoid glycoside has a general structural formula as represented by formula (1), wherein each of R...  
WO/2022/089593A1
The present application relates to the technical field of pharmaceutical chemistry, and in particular relates to a double salt compound of a flavone glycoside-organic amine anti-tumor agent, a preparation method therefor and the use ther...  
WO/2022/089600A1
The present application relates to a double salt compound of flavonoid glycoside and an organic amine antimicrobial agent. The flavonoid glycoside has a structural general formula represented by the following formula (1), wherein R1-R9 a...  
WO/2022/089598A1
A flavonoid glycoside and organic amine neuroagonist double salt compound, a preparation method therefor, and an application thereof, a pharmaceutical composition containing a therapeutically effective amount of the double salt compound ...  
WO/2022/079637A1
Analogues of oleuropein and oleacein and pharmaceutically acceptable salts thereof and processes for the preparation of these compounds are disclosed. The invention further relates to use of oleuropein and oleacein analogues for the trea...  
WO/2022/067196A1
This invention is directed to compositions comprising dibenzo-alpha-pyrones (DBPs, Urolithins) and DBP glycosides, and methods of improving the immune system, providing immuno-protection, and/or treating immunosuppression in a subject wi...  
WO/2022/052393A1
A method for separating and preparing paeonidin-3-O-(6-p-coumaroyl) glucoside and malvidin-3-O-(6-p-coumaroyl) glucoside. Two high-purity acylated paeonidin and malvidin anthocyanin monomers are purified and separated from grapes by mean...  
WO/2022/052394A1
Disclosed in the present invention is a method for preparing a delphinidin-3-O-(6-O-p-coumaroyl) glucoside by separation. By means of steps such as extraction, macroporous resin purification, extracting, preparative liquid chromatography...  
WO/2022/040802A1
Disclosed are novel glycosylated psilocybin derivative compounds that activate the 5-HT2A cell surface receptor and increase intracellular calcium concentration with a profile different from that of psilocin, and pharmaceutical and recre...  
WO/2022/035752A1
Disclosed are C16 amide derivatives of C2'-epi-amphotericin B (C2'epiAmB) and salts thereof characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions, comprising any...  
WO/2022/010252A1
The present invention relates to an alkylene-oxide-added polyol composition, a polyurethane using same, and a hot-melt adhesive comprising same, and, more specifically, to an alkylene oxide-added polyol composition, a polyurethane using ...  
WO/2022/008647A1
Diosmin preparation method.  
WO/2022/003181A1
The present invention relates to urea derivatives of polyene macrolides having the following chemical formula: wherein: - R1 is hydrogen or an alkyl or aryl or acyl group, and R2, independently of R1, is hydrogen or an alkyl or aryl or a...  
WO/2021/263039A1
This disclosure is directed, at least in part, to AMPK activators useful for the treatment of conditions or disorders associated with AMPK. In some embodiments, the condition or disorder is associated with the gut-brain axis. In some emb...  
WO/2021/261663A1
According to the present invention, provided are a benzimidazole-carbohydrate conjugate compound represented by chemical formula 1, a preparation method therefor, and a use thereof as an anticancer or antiviral agent. [Chemical formula 1...  
WO/2021/237364A1
The present document describes compounds of Formula (I): or a pharmaceutically acceptable salt thereof, methods of making the same, and methods of using the same for the treatment or prevention of numerous conditions, including ulcerativ...  
WO/2021/234200A1
The invention relates to a binary complex formed by an organic zinc chelate as an active agent and at least one flavonoid as a zinc ion carrier ionophore, wherein the complex is formed by the cation Zn2+ bound through four ligands to fla...  
WO/2021/227291A1
Disclosed is an abamectin B2a solvated crystal, which belongs to the technical field of agricultural chemicals. By means of X-ray single crystal diffraction, it is determined that: the crystal structure is a monoclinic system; a space gr...  
WO/2021/226002A1
The present disclosure relates to compounds of Formula (I) or Formula (II), which inhibit Gal-3, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compo...  
WO/2021/201669A1
Disclosed herein is a polymeric amphoteric surfactant compound of formula (I).  
WO/2021/187679A1
The present invention relates to a composition, comprising a sea cucumber-derived saponin compound, for preventing, alleviating, or treating neuropathy. More specifically, the sea cucumber-derived saponin compound of the present inventio...  
WO/2021/183758A1
Defined herein are immunomodulating Formula (1) compounds wherein R, R0, R1, R2,R3 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The inventi...  
WO/2021/183759A1
Defined herein are immunemodulating Formula (1) compounds wherein R1, R2, R3, and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention al...  
WO/2021/183762A1
Defined herein are immunomodulating Formula (1) compounds stereoisomers thereof, and pharmaceutically acceptable salts thereof; wherein R0, R1, R2, R10, W, Ring C and n are as defined herein, stereoisomers thereof, and pharmaceutically a...  
WO/2021/183754A1
Defined herein are immunomodulating Formula (1) compounds, wherein R1, R2 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also i...  
WO/2021/172955A1
The present invention provides an intermediate useful for the synthesis of an SGLT inhibitor and a method for preparing an SGLT inhibitor using same. According to the present invention, by developing a compound of chemical formula 5 corr...  
WO/2021/169606A1
Disclosed in the present invention are an avermectin B2a ethylenic derivative, and a preparation method therefor and the use thereof. The structural formula of the avermectin B2a ethylenic derivative is as represented by formula I. The c...  
WO/2021/170621A1
The present invention relates to a biotechnological method for producing a C-glycoside of interest. The invention further relates to the use of a sialylated C-glycoside as a donor in an enzymatic glycosylation reaction. The present inven...  
WO/2021/160670A1
The present invention relates to a 3'-ketoglycoside compound defined by formula (I) and its use for controlled release of alcohols, in particular alcohols showing an insect repellent effect. It relates also to a process for preparing the...  
WO/2021/138847A1
Provided herein is macrolide compound and its use of treatment chronic respiratory disease. Specifically, it provides the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers and application thereof. The compounds...  
WO/2021/142312A1
Novel compositions comprising heparinoid-related compounds, manufacturing and treatment methods, kits and dosage forms thereof, are provided.  
WO/2021/131900A1
The purpose of the present invention is to provide a prenylflavonoid glycoside in which two or more hexoses have been bonded to isoxanthohumol or 8-prenylnaringenin, a method for producing the same, a method for producing a prenylflavono...  
WO/2021/122719A1
The present invention relates to a process for preparing a compound of formula (I), wherein said process is suitable for large scale synthesis.  
WO/2021/121362A1
Disclosed are a furaneol glycoside compound, a pharmaceutical composition thereof, a preparation method therefor, and an application thereof. Specifically disclosed are a compound as represented by formula A-1, a pharmaceutically accepta...  
WO/2021/113357A1
Disclosed herein are new salts and polymorphs of cethromycin for the treatment of diseases due to infection by bacteria and certain protozoans, including, for example, malaria, Babesosis, Toxoplasmosis, diarrheal disease, respiratory dis...  
WO/2021/098843A1
An abamectin extraction method, comprising: performing extraction on abamectin residues using a dynamic ultrasonic extraction method, and concentrating the obtained liquid extract into extractum; performing extractive desugarization on t...  
WO/2021/081634A1
A combination that includes: a flavonoid, for example in an amount from about 0.1 g to about 1.5 g; and one or more of: ascorbic acid, ascorbate, or a combination thereof, for example in an amount from about 0.2 g to about 2.0 g; N-acety...  
WO/2021/085293A1
The present invention addresses the problem of providing an external skin preparation for ameliorating cellulite and a method for ameliorating cellulite, which can ameliorate cellulite in a simple manner without requiring special equipme...  
WO/2021/075904A1
The present invention relates to: a newly developed triazine-based amphiphilic compound; a preparation method therefor; and a method for extracting, lysing, stabilizing, crystallizing or analyzing membrane proteins by using same. In addi...  
WO/2021/062555A1
Topical formulations comprising one or more cannabinoids, one or more terpenes, and one or more flavonoids; and methods and uses thereof for the treatment of an integumentary wound, wherein the one or more cannabinoids comprise tetrahydr...  
WO/2021/062482A1
The invention relates to compounds that have antiviral activity, particularly 4-oxochromane derivatives that have antiviral activity against viruses of the Family Flaviviridae. Methods of treating viruses with the 4-oxochromane compounds...  
WO/2021/059058A1
A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a c...  
WO/2021/037077A1
Patentiflorin A analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.  
WO/2021/031594A1
Disclosed are a novel aromatic ring compound represented by general formula (I), an isomer, a prodrug, a solvate, a pharmaceutically acceptable salt and a pharmaceutical composition thereof, and use thereof for preparing medicaments for ...  

Matches 1 - 50 out of 4,763