Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 6,622

Document Document Title
WO/2021/062555A1
Topical formulations comprising one or more cannabinoids, one or more terpenes, and one or more flavonoids; and methods and uses thereof for the treatment of an integumentary wound, wherein the one or more cannabinoids comprise tetrahydr...  
WO/2021/062482A1
The invention relates to compounds that have antiviral activity, particularly 4-oxochromane derivatives that have antiviral activity against viruses of the Family Flaviviridae. Methods of treating viruses with the 4-oxochromane compounds...  
WO/2021/059058A1
A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a c...  
WO/2021/037077A1
Patentiflorin A analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.  
WO/2021/031594A1
Disclosed are a novel aromatic ring compound represented by general formula (I), an isomer, a prodrug, a solvate, a pharmaceutically acceptable salt and a pharmaceutical composition thereof, and use thereof for preparing medicaments for ...  
WO/2021/030183A1
Disclosed are compositions comprising a polyene macrolide antibiotic and an azole antifungal, and packaged pharmaceutical products comprising the disclosed compositions. Also disclosed are methods of treating systemic fungal infections c...  
WO/2021/022690A1
The present invention relates to the field of chemical synthesis, in relates particular to a nucleoside salt represented by formula (III) or formula (IV), and a preparation method therefor. The method provided by the present invention is...  
WO/2021/025444A1
Despite various functions discovered of polyphenol-based compounds in regulating biological responses, such compounds, due to difficulty in procuring same in sufficient amounts with a high enough purity to permit application in pharmaceu...  
WO/2021/026450A1
Disclosed are C16 ester derivatives of C2'epi-amphotericin B (C2'epiAmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the C 16 ester derivati...  
WO/2021/013155A1
Disclosed are a new glycosyl donor, a preparation method therefor, and an application thereof. Specifically, a glycosyl donor represented by formula (I), a preparation method therefor, and a use of the glycosyl donor represented by formu...  
WO/2021/008549A1
The present invention belongs to the field of pharmaceutical chemistry. Specifically, the present invention relates to a novel compound and a pharmaceutical composition. The novel compound has a structural formula represented by formula ...  
WO/2020/255865A1
[Problem] The objective of the present invention is to provide topical composition having a much higher whitening effect. [Solution] This topical composition, characterized by comprising (A) ascorbic acid and/or a derivative thereof, (B)...  
WO/2020/251862A1
The present invention provides methods and kits to improve the signal from sialic acids labeled with the dye 1, 2-diamino-4, 5-methylenedioxybenzene ("DMB"). The methods include labeling the sialic acids with DMB in an aqueous solution c...  
WO/2020/244148A1
The present application relates to a doramectin polymorph. Specifically, the present application relates to doramectin crystal form A, crystal form B, and a preparation method thereof. The polymorph can be obtained by dissolving doramect...  
WO/2020/244253A1
Disclosed is an application of a small molecule compound or a pharmaceutically acceptable salt thereof in the preparation of an anti-tumor metastasis drug. The structure of the compound is as shown in formula (I). The small molecule comp...  
WO/2020/241759A1
[Problem] To provide a novel medicine for preventing and/or treating influenza virus infection or corona virus infection. [Solution] According to the present invention, provided are an anti-influenza virus agent, an anti-corona virus age...  
WO/2020/238528A1
The invention relates to an intermediate TSL-1502M of a PARP inhibitor and a preparation method thereof. The structural formula of the intermediate is as shown. The preparation method includes the following step: under the action of sodi...  
WO/2020/212760A2
Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory/ infections disease of the anterior surface of the eye...  
WO/2020/198883A1
Transdermal medicaments containing cannabidiol (CBD) for use in the amelioration of conditions, including anxiety, depression, pain, inflammation, epilepsy, parkinson's disease, oxidative injury and nausea; and a method for preparing same.  
WO/2020/198578A1
The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant comp...  
WO/2020/194237A1
Methods of rapidly inhibiting efflux from a cell, sensitizing a drug-resistant cell to a drug and treating a subject with a drug-resistant pathology, by administering tetrahydrocannabinolic acid (THCa), cannabidiol (CBD) or a combination...  
WO/2020/170840A1
The present invention addresses the problem of providing a novel crystal of 2-O-α-D-glucosyl-L-ascorbic acid and a method for producing the crystal. The problem is solved by providing a crystal of the potassium salt of 2-O-α-D-glucosyl...  
WO/2020/160443A1
Methods for preparing a polyene macrolide antifungal with improved aqueous solubility. The method involves providing a polyene macrolide antifungal having a carboxylic acid group; activating the carboxylic acid group; introducing a prima...  
WO/2020/132480A1
Compositions for treating an autoimmune, inflammatory, fibrotic, or proliferative disease or disorder comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, ...  
WO/2020/127843A1
The present disclosure relates to a compound of Formula (I): or anyone of its metabolites or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein each ...  
WO/2020/119773A1
The present disclosure relates to the field of medicine, and specifically relates to an amphotericin B peptide derivative and a preparation method therefor. The amphotericin B peptide derivative has a broad-spectrum and highly effective ...  
WO/2020/115661A1
A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a c...  
WO/2020/104697A1
The present invention relates to a synthetic saccharide of general formula (I) that is related to Clostridium difficile PS-II cell-surface polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical...  
WO/2020/106636A1
Provided are 13-membered macrolides for the treatment of infectious diseases. The 13- membered macrolides described herein are azaketolides. Also provided are methods for preparing the 13-membered macrolides, pharmaceutical compositions ...  
WO/2020/106780A1
Provided herein are compounds or payloads, linker-payloads, antibody-drug conjugates, and compositions, and methods for the treatment of diseases and disorders associated with the liver X receptor, including bis-octahydrophenanthrene car...  
WO/2020/106627A1
Provided are 13-membered macrolides for the treatment of infectious diseases. The 13-membered macrolides described herein are azaketolides. Also provided are methods for preparing the 13- membered macrolides, pharmaceutical compositions ...  
WO/2020/079224A1
This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using ...  
WO/2019/075214A3
Disclosed are methods of treating cystic fibrosis using AmB and a sterol or compositions comprising AmB and a sterol. Also disclosed are methods of increasing the pH of airway surface liquid in a patient having cystic fibrosis using AmB ...  
WO/2020/057546A1
A cyclic dinucleotide analogue, a pharmaceutical composition thereof, and application. A cyclic dinucleotide analogue (I), an isomer thereof, a prodrug, a stable isotope derivative, or a pharmaceutically acceptable salt has the following...  
WO/2020/048049A1
Disclosed are a method for preparing a Luo Han Guo sweetner composition from Siraitia grosvenorii and a use thereof. The method for extracting the sweetener composition from Siraitia grosvenorii preferably comprises the following steps: ...  
WO/2020/050663A1
The present invention relates to a method for chemical production of 3,6-anhydro-L-galactitol (L-AHGol), which is a novel sugar alcohol, and agarobititol (ABol), which is a disaccharide having the same agarobititol as a reductant end the...  
WO/2020/051465A1
Disclosed are derivatives of amphotericin B (AmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the AmB derivatives, therapeutic methods of us...  
WO/2020/038279A1
A substituted pyrazole compound represented by formula I, and a preparation method, a pharmaceutical composition, and use thereof. The compound has good stability, excellent solubility, small cell toxicity, and a significant effect on ne...  
WO/2020/040233A1
The present invention provides a method for obtaining a specifically-shaped crystal (specifically, spherocrystal) of a compound with good reproducibility. This method for producing a specifically-shaped crystal (specifically spherocrysta...  
WO/2020/035553A1
The present invention is directed to a process for purifying natamycin, to an epoxide polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macr...  
WO/2020/035552A1
The present invention is directed to a process for purifying natamycin, to an all-trans polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric ma...  
WO/2020/032752A1
The present invention relates to a catechin compound or a pharmaceutically acceptable salt thereof, and a use thereof, and a catechin compound or a pharmaceutically acceptable salt thereof of the present invention is very effective in th...  
WO/2020/032744A1
The present invention relates to a catechin compound or a pharmaceutically acceptable salt thereof, and a use thereof, and a catechin compound or a pharmaceutically acceptable salt thereof of the present invention is very effective in th...  
WO/2020/029168A1
A natamycin superfine powder, a preparation method therefor and the use thereof. The natamycin superfine powder is a solid powder, and has no fixed shape under a transmission electron microscope, and no less than 95% of the shape size is...  
WO/2020/021574A1
Pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof: Formula (I) for modulating one or more cytokines such as: Tumor necrosis factor-α (TNF-α), Interleukin-1 (IL-1), Interleuki...  
WO/2020/005111A1
The invention relates to chemistry and pharmacology, specifically to polymer complexes of a macrolide antibiotic. The claimed substance is a product of the interaction of a macrolide antibiotic with a copolymer of acrylamide and 2-acryla...  
WO/2019/241895A1
Provided are transgenic organisms, such as plants and plant parts, cells, and related compositions and methods for producing and monitoring the genotype for enhanced production of montbretin A and/or its precursors. For example, provided...  
WO/2019/241947A1
Disclosed is a method of separating and purifying icariin from Epimedium extract, relating to the technical field of separating and purifying a single component from a plant extract, and is intended to address the issues of complicated p...  
WO/2019/241461A1
The present disclosure relates to compounds of Formula (1), which inhibit Gal-3, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods making and using such compounds and compositions.  
WO/2019/030367A8
The present invention relates to a method for the synthesis of compounds useful in the preparation of antibody drug conjugates (ADC), namely, monoprotected dimeric bifunctional prodrugs based on duocarmycin analogs. In a further aspect, ...  

Matches 1 - 50 out of 6,622