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Matches 1 - 50 out of 4,834

Document Document Title
WO/2024/036254A2
The present invention relates to a process for producing compounds of formula I and/or formula I'. The present invention also relates to a process of selectively cleaving the main ring of a compound of formula IV to provide the starting ...  
WO/2024/030662A1
The disclosure provides host cells engineered to express non-naturally occurring polyketide synthases that produce b-keto-d-lactones (BKDLs); methods of generating such host cells, and methods of producing BKDLs employing the host cells.  
WO/2024/007104A1
Provided is use of a glucopyranoside compound for enhancing the sweetness of a sweetness regulator and reducing the amount of the sweetness regulator used in consumables.  
WO/2024/005460A1
The present invention provides a compound comprising a self-immolative group and a ligand-drug conjugate comprising same. According to the present invention, an active material may be stably delivered up to a target site, and the active ...  
WO/2024/005461A1
The present invention provides a novel linker compound and a ligand-drug conjugate therefor. This can stably deliver an active ingredient to a target site and rapidly release the active ingredient at the target site, and thus can increas...  
WO/2023/250513A1
Provided are 13-membered macrolides that can be used to treat proliferative diseases such as cancer as well as genetic diseases that are associated with a premature termination codon mutation or other nonsense mutations. The compounds ca...  
WO/2023/245037A1
The disclosure provides processes for preparing the compound of formula (VIa-1) and pharmaceutically acceptable salts thereof. Intermediates useful in preparing the compound of formula (VIa-1) are also provided.  
WO/2023/236534A1
Provided is a catalyst for selectively reducing spinosad J, relating to the technical field of spinosad preparation. The weight of active components of the catalyst accounts for 1%-10% of the weight of the catalyst, and the active compon...  
WO/2023/236453A1
The present invention belongs to the field of compounds, and discloses a method for preparing albiflorin-6'-O-benzenesulfonate. The method comprises the following steps: taking a medicinal material that is rich in albiflorin as a startin...  
WO/2023/240221A2
High yield separation and purification of one or more cannabinoid glycoside species from a complex mixture of cannabinoids. In one preferred aspect, the novel systems and methods of the invention can separate one or more cannabinoids and...  
WO/2023/233301A1
Disclosed herein are macrolide compounds having senolytic activity. These compounds selectively target senescent cells, and may be used to reduce or eradicate senescent cells in a subject, and/or delay the onset of aging. These compounds...  
WO/2023/209440A1
The present disclosure relates to tellurophene analogues of small molecules, and methods of detecting small molecules using their tellurophene analogues. The present disclosure further relates to compositions and kits comprising tellurop...  
WO/2023/205615A1
Disclosed herein are ionic liquid composition(s) of amphotericin B comprising amphotericin B; a complexing agent component; a solvent component comprising acidified solvent(s); and a solubilizing component. Disclosed composition(s) compr...  
WO/2023/193601A1
A method for simultaneously separating and purifying myricetin-3-O-(2"-O-galloyl)-α-L-rhamnoside and myricetin-3-O-(4"-O-galloyl)-α-L-rhamnoside from myrica rubra leaves and the use of the above-mentioned compounds in the preparation o...  
WO/2023/125818A1
The present invention relates to the technical field of pharmaceutical chemistry, in particular to a 8-debenzoylpichlorin-6'-O-benzenesulfonate, a preparation method therefor, and the use thereof in treating Sjögren's syndrome and rheum...  
WO/2023/118961A1
The present disclosure is directed toward drugs and toxins functionalized by at least one saccharide, sulfate or sulfonate; drug conjugates comprising said drugs or toxins and a cleavable linker; and targeted conjugates comprising said d...  
WO/2023/118061A1
The present invention relates to a process of purification of a crude compound of formula (I) wherein it comprises an isolation step of said crude compound of formula (I) including: (i) a solubilization step of said crude compound of for...  
WO/2023/090764A1
The present invention relates to a wallpaper composition and wallpaper from which a flavor ingredient is released by heat and, more particularly, to a wallpaper composition and wallpaper, comprising a compound which includes a moiety der...  
WO/2023/082574A1
The present invention provides a method for synthesizing selamectin, specifically comprising: oxidizing doramectin by means of manganese dioxide, oximating and desugaring same by using a hydroxylamine hydrochloride aqueous solution in a ...  
WO/2023/072069A1
Disclosed is the new use of Isorhoifolin and a derivative thereof. Isorhoifolin and the derivative thereof can be used for promoting the regeneration of damaged brain neurons and retinal nerves.  
WO/2023/040733A1
Disclosed in the present invention are a class of baicalein derivatives, and a preparation method therefor and the uses thereof. The structure of the baicalein derivative of the present invention is as represented by the following genera...  
WO/2023/035479A1
Disclosed is a traditional Chinese medicine composite which has the effect of promoting directional differentiation of stem cells into cardiomyocytes, comprising: syngnathus, pilose antler, hippocampus, ginseng, astragalus membranaceus, ...  
WO/2023/038852A1
Defined herein are immunomodulating Formula (1) compounds, wherein R, R0, R1, R2 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention...  
WO/2023/018326A1
Provided are compounds of formula (I) and (II), which are useful as surfactants. Also provided are methods of preparing compounds of formula (I) and (II).  
WO/2023/014082A1
The present invention relates to a novel thalidomide-based compound derivative having significantly improved water solubility due to the introduction of a sugar or sugar derivative into lenalidomide or pomalidomide, which are thalidomide...  
WO/2023/000516A1
The present invention provides a purification method for paeoniflorin-6-O'-benzene sulfonate. According to the purification method, the purification process for paeoniflorin-6-O'-benzene sulfonate can be reduced, and impurities, such as ...  
WO/2023/000517A1
Provided in the present invention is a method for preparing paeoniflorin-6-O'-benzene sulfonate. The method uses crude paeoniflorin instead of paeoniflorin as a raw material, which more complies with actual requirements of an industrial ...  
WO/2023/002349A1
A chlorinated 4'-alkylumbelliferyl α-D-glucopyranoside represented by the structural formula (I) One of R1 and R2 is Cl and the other is H. R3 represents an alkyl group having 1 to 12 carbon atoms. A method of assessing efficacy of a st...  
WO/2023/000518A1
Provided in the present invention is a method for synthesizing a paeoniflorin derivative of formula III. The synthesis method can obviously reduce the use amount of a reaction solvent, shortens the reaction time, has the characteristics ...  
WO/2023/285323A2
The invention relates to a process for the production of amcipatricin diascorbate and the use of the same for an improved treatment of invasive fungal infections having proof/prevalence of resistance to traditional antifungal agents.  
WO/2023/280857A1
Disclosed is a process preparing diosmin and flavonoid fraction by direct oxidation of hesperidin.  
WO/2023/274313A1
The present invention provides an amphotericin B semi-synthetic derivative, and a preparation method therefor and a use thereof. Specifically, disclosed are a compound having a structure as shown in formula (V), as well as a water-solubl...  
WO/2023/275715A1
The present invention provides compounds of Formula X-1, X-2, X-3, or X-4, or metabolites of Compound 1 or metabolites of a compound of Formula 3-A or 3-B, including compositions and salts thereof, which are useful in the prevention and/...  
WO/2022/258692A1
The present invention generally relates to the field of pesticides. More specifically, the present invention relates to novel spinosyn compounds having advantageous properties, processes for their preparation, and their use as pesticides.  
WO/2022/256920A1
Provided herein are β-1,3-linked biopolymers (acholetin polysaccharides). Furthermore, provided herein are enzymatic methods and systems for producing β-1,3-linked oligosaccharides and polysaccharides using β-1,3-N-acetylglucosaminide...  
WO/2022/255416A1
The purpose of the present invention is to provide: a method for producing a catechin conjugate with high efficiency by a semi-synthesis process; and an intermediate for the production of the catechin conjugate. Provided is a method fo...  
WO/2022/254868A1
Provided are a novel active ingredient derived from carob and usage thereof. The present invention is a compound represented by formula (I) or a salt thereof, or a solvate of the compound or the salt.  
WO/2022/250322A1
The present invention relates to a novel compound isolated from spinach, and a composition comprising same for preventing or treating inflammatory diseases, and, more particularly, to a novel medicagenic acid glycoside compound isolated ...  
WO/2022/251730A1
Provided are 13-membered ribosome targeting compounds that can be used to treat genetic diseases, including genetic diseases that are associated with a premature termination codon mutation or other nonsense mutation. The compounds can in...  
WO/2022/240098A1
The present invention identifies moisturizing and physiological activities of agarobiose, and provides a novel substance alkyl-agarbioside for maintaining moisturization activity of agarbiose and securing both pH and temperature stabilit...  
WO/2022/223779A1
The present invention generally relates to the field of pesticides. More specifically, the present invention relates to novel spinosyn compounds having advantageous properties, processes for their preparation, and their use as pesticides.  
WO/2022/226425A1
The present disclosure provides compounds useful for enzymatic glycan remodeling of a glycoprotein. Also provided is a method for remodeling a glycoprotein using M6P-glycan oxazolines in a one-pot deglycosylation/transglycosylation proce...  
WO/2022/224619A1
[Problem] To, inter alia, discover an agent including an active ingredient derived from a natural product that maintains the softness of the skin and imparts resilience (firmness) to the skin texture. [Solution] An agent for enhancing co...  
WO/2022/197528A1
Novel selective estrogen receptor degraders (SERDs) according to the formula: and pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof, wherein R is selected from or.  
WO/2022/174190A1
Novel sophorolipid derivatives with enhanced antimicrobial activity have been identified as disinfecting active ingredients. These derivatives are produced through a fermentation of Starmerella bombicola utilizing dextrose and an oleoche...  
WO/2022/168846A1
A barrier function improver which contains methylhesperidin as an active ingredient, and a barrier function improver composition which contains said barrier function improver and a pharmaceutically acceptable carrier.  
WO/2022/151978A1
Provided in the present invention is a pharmaceutically active ingredient extract extracted from Polygala japonica Houtt., which extract comprises a flavonol compound of the following formula (I) structure as a first active ingredient, a...  
WO/2022/134385A1
The present invention relates to the technical field of agricultural chemicals and preparation. Specifically, disclosed is a purification method for 4"-(s)-methylamino abamectin B2a benzoate. The purification method comprises the followi...  
WO/2022/133314A1
Disclosed herein are enzymatic and modified host cell methods for prepared modified indole alkaloids. Also disclosed herein are modified indole alkaloids and their therapeutic use for treating diseases and disorders.  
WO/2022/094694A1
Functional food comprising montbretin A and use of the functional food for limiting polysaccharide processing in a human subject and for treating conditions treatable by inhibiting pancreatic a-amylase.  

Matches 1 - 50 out of 4,834