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WO/1997/032571A1 |
Graphitic nanotubes, which include tubular fullerenes (commonly called 'buckytubes') and fibrils, which are functionalized by chemical substitution or by adsorption of functional moieties. More specifically the invention relates to graph...
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WO/1997/026240A1 |
Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structure (I) or (IA) or (IB) including pharmaceutically acceptable sa...
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WO/1997/025302A1 |
A perfume composition containing 5-benzylhexanol-2, which has a flowery fragrance and is excellent in stability, so that a blend containing the composition is excellent in lingering scent.
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WO/1997/019038A1 |
A perfluoroalkylation method and a reagent therefor are disclosed. The method comprises contacting a material of formula RfH and a base (or a species capable of generating a base) with a substrate bearing at least one electrophilic funct...
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WO/1997/014500A1 |
The invention relates to a chiral solid catalyst, comprising an acid BEA topology zeolite provided with a metal-binap complex, and to a process for the production of substantially enantiomerically pure products from prochiral starting ma...
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WO/1997/011044A1 |
The invention concerns a process for separating solids from aqueous 1,4-butyne diol solutions by trickling a solids-containing aqueous butyne diol solution through a column and so bringing it into contact with a solvent which has lower d...
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WO/1997/007085A1 |
Disclosed is an improved process for the preparation of 1,4-butenediol by the hydrolysis of 3,4-epoxy-1-butene (EpB) wherein a mixture of EpB and water is contacted with a catalyst comprising a catalyst support material and copper in a p...
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WO/1997/001536A1 |
Compounds of formula (I), wherein Y is -CH- or -N-; R1 is hydrogen, halogen, a CF3 group, (C3-4) alkyl or (C1-4) alkoxyl; R2 is hydrogen, halogen, hydroxyl, a CF3 group, (C3-4) alkyl or (C1-4) alkoxyl; each of R3 and R4 is hydrogen or (C...
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WO/1996/033612A1 |
The present invention is directed to compounds useful as moth attractants and to methods for controlling populations of the tomato moth Scrobipalpuloides absoluta with these compounds. The compounds are 3,8,11-tetradecatrienyl acetates, ...
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WO/1996/028404A1 |
Novel trifluoromethylated intermediates are provided which are useful in synthesizing trifluoromethylated organic compounds. Specifically, compounds of the formula: CF3CCl=CHCH2X are provided, which compounds are versatile intermediates ...
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WO/1996/025420A1 |
A chiral, organometallic compound which, at a molecular level, has no C2 symmetry and comprises a carbon to carbon bond joining a chiral carbon atom to a carbon atom of a cyclopentadiene ring that is non-symmetrically substituted. Exampl...
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WO/1996/020913A1 |
Novel trienoic retinoid compounds having activity for retinoic acid receptors and retinoid X receptors are provided. Also provided are pharmaceutical compositions incorporating such compounds and methods for their use.
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WO/1996/020910A1 |
There is disclosed a method for optical resolution of 1,2-phenylethanediol, comprising the reaction of a racemic mixture of (R,S)-1,2-phenylethanediol, represented by formula (I), with an acetyl donor in the presence of an enzyme, to pro...
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WO/1996/019428A1 |
Biocidal alcohols of general formulae (I) and (II) are described in which R2 is selected from C1-C8 alkyl, uninterrupted or interrupted by oxygen and/or sulphur atoms, C2-C8 alkenyl and C3-C8 alkynyl, R1 is a significance of R2, independ...
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WO/1996/017819A1 |
The object of the present invention is to provide asiatic acid derivatives (I), its pharmaceutically acceptable salts or esters. Asiatic acid, its trisaccharide asiaticoside and madecassic acid, extracted from Centella asiatica have been...
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WO/1996/016010A1 |
The invention provides an improved process for preparing a halogenated alcohol of formula (I): CX1X2X3-CH(OH)CH=C(CH3)2, wherein X1, X2 and X3 are halo, which comprises reacting a compound of formula (II): CX1X2X3H with 3-methylbut-2-en-...
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WO/1996/012694A1 |
Aldehydes, ketones, esters and lactones may be reduced using a reductant system consisting of a silane derivative and a metal hydride to give good yields of the corresponding alcohols. The reductant system used in the method enables pref...
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WO/1996/010003A1 |
The present invention relates to a novel process for preparing (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, also known in the art as (E)-(p-fluorophenethyl)-3-fluoroallylamine, novel intermediates thereof, a novel process fo...
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WO/1996/009282A1 |
The invention provides low viscosity iodinated aryl compounds, useful as X-ray contrast agents, of formula (I), wherein n is 0 or 1, and where n is 1 each C6R5 moiety may be the same or different; each group R is a hydrogen atom, an iodi...
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WO/1996/009285A1 |
The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula (I) (wherein each C6R5 moiety may be the same or different; each R denotes a hydrogen or iodine atom or a group M, two or three non-adjace...
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WO/1996/004243A1 |
A process for purifying vitamin A consisting of heating a vitamin A preparation in an inert atmosphere, at a temperature below 170 �C and a pressure of less than 4 mm of mercury, said heating taking place in a vessel shielded from ligh...
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WO/1996/002619A1 |
The invention concerns unsaturated fats with improved low-temperature behaviour which are obtained by: (a) dissociating lauric acid oils into fatty acids and glycerol; (b) subjecting the resultant dissociated fatty acids to fractionated ...
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WO/1996/001242A1 |
A process is disclosed for the selective hydrogenation of butine-2-diol(1,4) to butene-2-diol(1,4) using a palladium catalyst to which copper and zinc or silver and zinc are added as doping agents. In the preferred embodiment, it has bee...
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WO/1996/000768A1 |
The proposal is for unsaturated fatty substances with improved cold behaviour obtained by (a) transesterifying a new low stearic (LS) sunflower oil with an oleic acid content of over 85 wt.% and a stearic acid content of under 3 wt.%, an...
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WO/1996/000708A1 |
This invention relates to methods for preparing alkylating agents and use of the agents prepared. In particular, this invention relates to preparation methods for hydroxy halide and organooxy halide alkylating agents and their use for al...
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WO/1996/000709A1 |
This invention is a process for preparing chlorohydrins by reacting a chlorinating species, such as hypochlorous acid, with at least one unsaturated organic compound, such as propylene or butylene, at a pH of greater than 6.0. The chlori...
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WO/1995/033782A1 |
A function-containing fluoroolefin represented by the following general formula: CH2 = CFCF2-Rf6-(CH2)k-X2 (wherein X2 represents -CH2OH, (a) or (b); Rf6 represents C1-C40 fluoroalkyl or -ORf7; Rf7 represents C1-C40 fluoroalkylene or C3-...
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WO/1995/032937A1 |
A method for the enantioselective reduction of prochiral ketones using catalytic amounts of tetrahydroindeno[1,2-d][1,3,2]oxazaboroles of formula (II) is disclosed. The oxazaboroles can be generated in situ from the corresponding cis-1-a...
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WO/1995/031420A1 |
A separating agent which, when used as the packing material for reversed-phase liquid chromatography, is excellent in the stability of the base line in the mobile phase and is increased in the number of the steps of the detected peak in ...
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WO/1995/030636A1 |
A method for preparing octa-2,7-dien-1-ol by means of a hydrodimerisation reaction between 1,3-butadiene and water in the presence of a transition metal in metal form or in the form of a compound of said metal, at least one phosphine and...
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WO/1995/028374A1 |
A novel glycerol derivative and a process for producing the same, and a process for producing a triazole derivative. Specifically the invention provides an optically active 2-arylglycerol derivative that is novel and useful as an interme...
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WO/1995/026948A1 |
Method for preparing an octa-2,7-dien-1-ol, wherein 1,3-butadiene is subjected to a hydrodimerization reaction with water in the presence of a transition metal, in the form of a metal or a compound thereof, a tertiary or quaternary water...
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WO/1995/025714A1 |
A method for synthesizing enantionmerically enriched chemical intermediates with predetermined chirality is described. The method comprises formation of a pseudoephedrine amide, followed by stereoselective alkylation at the 'alpha' carbo...
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WO/1995/021808A1 |
Dihydrocinnamic aldehydes may be prepared in high yields and with a good odour by catalytic dehydrogenation of dihydrocinnamic alcohols at moderate temperatures.
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WO/1995/021144A1 |
The invention relates to a process for producing 3-aryl propines in which alkines are reacted with benzyl halides in the presence of a palladium compound and weak bases, and to some novel 3-aryl propines.
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WO/1995/020563A1 |
Described are pharmacologically active leukotriene B4 derivatives of the general formula I in which R1 is CH2OH, CH3, CF3, COOR4 or CONR5R6, R2 is H or an organic-acid group with 1 to 15 C-atoms, R3 is H, a C1-C14 alkyl group, optionally...
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WO/1995/016658A1 |
Disclosed is a process for preparing allylic halides of the formula (I), wherein X is Cl, Br or I, for use as intermediates in the synthesis of substituted tetrahydrofuran azole anti-fungal agents.
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WO/1995/015939A1 |
Disclosed are compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R3 is alkyl, alkenyl, alkynyl, aryl, alkaryl, aralkyl, cycloalkyl, acyloxymethyl, alkoxy, alkoxymethyl, or alkyl substituted with ...
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WO/1995/014635A1 |
A process of preparing alkylene oxides comprises steps of: (1) optionally contacting metal hydroxide or oxide with chlorine to form a metal hypochlorite solution; (2) contacting chlorine with a solution of a metal hypochlorite at a tempe...
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WO/1995/011242A1 |
Compounds of formula (I), wherein m is 1-4; R1-R4 independently are hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, or I; R5 is hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, I, lower alkoxy or lower thioalkoxy of 1-6 carbons; R6 is h...
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WO/1995/011210A1 |
The invention concerns a method of producing fatty alcohols with an iodine number between 20 and 110 from vegetable oils, the alcohols consisting essentially of unsaturated fatty alcohols or mixtures of saturated and unsaturated fatty al...
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WO/1995/009139A1 |
A process for the oxidation of alkylaromatic compounds is provided. The process comprises oxidising a substrate alkylaromatic compound with a peroxygen compound in the presence of a source of cerium (III) or (IV), a source of bromide and...
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WO/1995/008989A1 |
Novel compounds of general structural formula (I) have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cer...
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WO/1995/007877A1 |
A process of preparing 2,3,5-trihalobenzaldehyde, which comprises the steps of (i) reacting a compound of formula (I), wherein Hal is halogen, with a di-C1-4 alkylformamide; (ii) allowing the resulting complex to rearrange; and (iii) que...
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WO/1995/007896A1 |
Novel hydroxy ethyl azolyl derivatives of formula (I), in which: X is hydrogen, halogen, alkyl with 1 to 4 carbon atoms or alkoxy with 1 to 4 carbon atoms; Z is halogen, alkyl with 1 to 4 carbon atoms, halogen alkyl with 1 to 4 carbon at...
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WO/1995/006746A1 |
A process for preparing acylated alcohols from alcohols is characterised in that the alcohol is reacted with a diketene in the presence of lipase. The process is particularly suitable for the enantioselective acetoacetylation of racemic ...
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WO/1995/004036A1 |
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to membe...
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WO/1995/000521A1 |
Thiadiazabicyclodecanes of formula (I) wherein, Z is oxygen or sulfur; R is an optional substituent and W is an optionally condensed or substituted phenyl radical and the salts, complexes and stereisomers thereof, have good selective pre...
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WO/1995/000480A1 |
The present invention is related to novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of formula (I) wherein W represents -C(=O)- or -CH(OH)-; R1 represents hydrogen or...
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WO/1994/029255A1 |
Compounds of general formula (I), stereoisomers and pharmaceutically acceptable salts thereof, wherein each of Z and Z' are independently H or F; Q is (a), CH(OH), (b); X is H, Br, Cl, F or CF3; Y is H, Br, Cl, F, OH, OR5, OC(O)R4, N3, C...
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