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JP3184627B2 |
PURPOSE: To efficiently produce the subject compound as an intermediate, in order to obtain a metal L-ascorbate in high yield and in high purity from 2-keto- L-gulonic acid. CONSTITUTION: The objective 2-keto-L-gulonic lower alkyl ester ...
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JP3179108B2 |
A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the following formula (I): (NeuAc- alpha (2-3)-pGal- beta (1)-(-X-)m-(-Y-)n-)p-Z ...
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JP3174189B2 |
PURPOSE: To obtain an immunological function suppressor, containing a specific enopyranose derivative which is a new substance as an active ingredient, having suppressing action on the immunological function with hardly any side effects ...
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JP2001506668A5 |
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JP2001506604A |
A class of molecules and methods that alter cell adhesion, inhibit cancer metastasis, and induce apoptosis. A method according to the present invention comprises bringing cells into contact with compounds that essentially consist of an a...
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JP3162224B2 |
PURPOSE: To provide a production method by which a sialic acid can be obtained in high yield without using any expensive natural material. CONSTITUTION: An acid (a), preferably sulfuric acid, is added to a solution containing colominic a...
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JP3160105B2 |
PURPOSE: To provide the subject compound useful as a key production intermediate for hydantocidin known as an excellent herbicidal substance. CONSTITUTION: The compound of formula I (R1 to R4 are H or hydroxyl- protecting group; X is hyd...
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JP2001106695A |
To obtain a (1-10C)alkyl 2-keto-L-gulonate as an intermediate for synthesizing L-ascorbic acid (vitamin C) in a sufficiently low residual water content rate and a short esterification reaction residence time. In the method for producing ...
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JP3141693B2 |
A ganglioside GM3 derivative having a fluorine atom at the 9-position of sialic acid represented by the formula: wherein R is an aliphatic lower acyl group, R<1> is a hydrogen atom or a lower alkyl group, R<2> to R<5> represent independe...
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JP2001502356A |
A method for synthesizing C-glycosides of ulosonic acids such as Neu5Ac, by which diastereocontrolled synthesis of alpha-C-glycosides of ulosonic acids is attained is disclosed. In the method of the present invention, an ulosonic acid su...
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JP2001501580A |
This invention pertains to nucleoside analogs that have antiviral activity and improved metabolic stability, compositions comprising them, and methods of antiviral treatment employing them. More particularly, this invention pertains to i...
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JP3098032B2 |
Imidazolidyl macrolides of the general structural Formula I: have been prepared from suitable precursors by alkylation and/or arylation at C-3= and/or C-4= of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammal...
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JP3085954B2 |
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JP3083521B2 |
The stereochemistry of sialylation of an acceptor saccharide to obtain an alpha (2-3) or alpha (2-6) linkage is controlled to favor the alpha anomer by use of an aromatic ester of the sialyl reagent. The resulting intermediate alpha (2-3...
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JP2000511160A |
The present invention provides fluorescent nucleosides carrying polycyclic aromatic hydrocarbons such as anthracene, phenanthrene, pyrene, stilbene, tetracene or pentacene. The subject nucleosides may be synthesized using a C-glycosidic ...
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JP2000191538A |
To obtain the subject suppressant useful as curing and preventing agents of diseases associated with crisis caused by adhesion of leucocytes to vascular endothelial cells by containing a compound containing a specific glucuronic acid der...
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JP3053205B2 |
Derivatives of antibiotics derived from the microorganism streptomyces lydicus subspecies tanzanius, referred to as antibiotics LL-E19020 alpha and beta (formula I), are produced by chemical reaction. The derivatives are also active anti...
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JP3043416B2 |
In a method of oxidising carbohydrates, particularly starch and dextrin, the oxidation is effected by molecular oxygen in an alkaline aqueous medium in the presence of a catalytic quantity of a metal ion selected from the metals of group...
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JP2000119292A |
To obtain an antiiflammatory agent or an antitumor agent and azalomycin SCs having a new structure.Azalomycin SCs are represented by the following general formula (R1 to R11 denote each independently hydrogen atom, a lower alkyl group or...
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JP3020111B2 |
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JP2000502565A |
The present invention relates to simplified synthesis, new carbohydrate-based products and practical use of different carbohydrate-based products. Examples of these are (Galalpha1-3Gal), GlcNAcbeta1-3Gal, alpha- or beta-glycosides thereo...
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JP3012263B2 |
Process for the preparation of a mixture of sucrose oxidation products containing a salt of sucrosetricarboxylic acid, which is obtained by reaction of sucrose with oxygen in an aqueous medium in the presence of a platinum metal/active c...
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JP2997419B2 |
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JP2996348B2 |
Process for splitting off DELTA <4>-unsaturated uronic acid from glycosaminoglycan, in which the glycosaminoglycan is treated with an iodine solution or with a bleaching reagent, or with a combination thereof.
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JP2989566B2 |
Perfluoroalkyl-C-glycosides (I) comprising a monosaccharide in which the anomeric carbon atom is bonded directly to a perfluoroalkyl and to a hydroxyl group, are new.
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JPH11292593A |
To obtain an ecologically acceptable admixture capable of obtaining a good balance among retarding property, plasticity, early mechanical strength and mechanical strength in 28 days. The admixture for a mineral binder contains a compsn. ...
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JPH11510795A |
The present invention discloses carbohydrates and carbohydrate analogs that bind to epidermal growth factor (EGF) receptors. Methods of using such carbohydrates or analogs for a variety of uses related to the EGF receptor are also provid...
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JPH11246586A |
To safely and simply obtain various radioactive ray-labeled oligosaccharides and a method for producing the oligosaccharide. This radioactive ray-labeled oligosaccharide is obtained by reacting a glycolipid, whose sugar chain part is lab...
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JP2949509B2 |
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JPH11510179A |
The present invention concerns analogues of Mannose-6-phosphate for use in promoting the healing of wounds or fibrotic disorders with reduced scarring.
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JP2944750B2 |
Neuraminic acid derivs. of formula (I) and (Ia) and their salts are new. A = O, S or C in (I) and N or C in (Ia). R1 = COOH, P(O)(OH)2, NO2, SOOH, SO3H, tetrazol, CH2CHO, CHO or CH(CHO)2. R2 = H, OR6, F, Cl, Br, CN, NHR6, SR6 or CH2X. X ...
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JPH11508548A |
Compounds of formula (I) in which X is the residue of a non-glycosidic aliphatic 1,2-diol; R1 is an S-configurated methyl substituted with one carboxyl residue and one other substituent; and R2 is hydrogen, C1-C12alkyl or C6aryl; as mime...
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JPH11180993A |
To simply and efficiently separate and recover sialic acids that can be utilized as a raw materials for food products, medicines, cosmetics, feed and the like in large amounts by effectively utilizing the desalination step for the whey o...
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JPH11507043A |
The present invention is directed to compositions for the treatment of respiratory infections caused by a bacteria selected from the group consisting of S. pneumoniae, H. influenzae, H. parainfluenza, Burkholderia (Pseudomonas) cepacia, ...
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JPH11147043A |
To simply and safely use an amine oxidant repeatedly by using a resin, comprising amine oxidant by adsorption as a catalyst to be used for the selective oxidation reaction of an organic compound having a primary hydroxyl group. When prep...
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JP2899577B2 |
The present invention provides a process for preparing lactone intermediates to 2',2'-difluoronucleosides whereby reversion back to the lactone's open chain precursor is minimized and the desired erythro enantiomer can be selectively iso...
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JP2899844B2 |
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JP2899576B2 |
The present invention provides a process for preparing lactone intermediates to 2',2'-difluoronucleosides whereby reversion back to the lactone's open chain precursor is minimized and the desired erythro enantiomer can be selectively iso...
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JP2892285B2 |
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JP2862489B2 |
Sugar alcohol sulphate esters (I) and their salts are new: A = tris(hydroxymethyl)methyl or a gp. derived by removing the 1-OH gp. from a sugar alcohol or deriv., with ≥ 1 OH gp. in A being replaced by OSO3H; X = -NR<1>CO-; -NHCONH-; -...
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JPH11502216A |
Bioactive fucopeptides and libraries of fucopeptides having advanced activities against P-selectin as sialyl Lewis X mimetics with IC50 values in the low mM range are synthesized by solid phase synthesis using para-acyloxymethylenzlidene...
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JPH1143439A |
To obtain the subject promoter useful as a tissue-repairing agent on inflammation, a therapeutic agent for vascular lesion such as arteriosclerosis or the like and a healing promoter for bum and wound by formulating an alginate oligosacc...
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JPH10513485A |
They are comprised of a series of derivatives of carbohydrates of a family of biologically active opiated agents, which present in their structure at least one residue of carbohydrate per opiate molecule, linked directly to a hydroxyl gr...
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JPH10513502A |
The present invention comprises colorant stabilizers and a colorant composition which includes a colorant and a colorant stabilizer. The colorant stabilizer imparts light-stability to the colorant so that the colorant does not fade when ...
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JP2834514B2 |
PURPOSE:To obtain an atoxic and useful substance free from elution by immobilizing glucuronic acid to the surface of insoluble carrier by amide bond. CONSTITUTION:An aromatic vinyl-based copolymer including a homopolymer of styrene or al...
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JPH10512247A |
Disclosed herein are antifungal compositions having an oligosaccharide that includes an N-acetylhexosamine residue linked beta (1}4) to a hexose and a biologically acceptable carrier. The isolation of the fungal enzyme chitin glucan beta...
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JP2825503B2 |
A process for purifying lysocellin which comprises mixing lysocellin solids with sufficient halogen acid to convert fatty acid ester salt impurities into water-soluble metal halogen salts and water-insoluble free fatty acids and to conve...
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JPH10296089A |
To provide a method for forming a glycosidic linkage which enables a control or three-dimensional control of a side reaction under mild conditions and is highly diastereoselective. In the method for forming a glycosidic linkage, a reacti...
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JP2817809B2 |
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JPH10279589A |
To obtain the subject new compound comprising an α (2-6) sialylated galactoside block and used for preparation of sialyloligosaccharide useful as an antigen having immunogenicity for preparation of antibody, an immunoadsorbent, etc., as...
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