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Matches 551 - 600 out of 10,291

Document Document Title
WO/2010/024762A1
A process for stereoselective synthesis of a β-phenylisoserine comprises reacting a carbonyl imine R-C=N-CO-OR1 with a protected α- oxyaldehyde X1O-CH2CHO in the presence of a chiral amine catalyst and oxidizing aldehyde so obtained.  
WO/2010/023892A1
Disclosed is a method of efficiently producing N-carboxy amino acid anhydride. The N-carboxy amino acid anhydride production method is characterized by including a process in which an amino acid organic salt compound and a carbonic acid ...  
WO/2010/023535A1
Disclosed herein are novel intermediates and process for large scale production of (S)- 3-[(1-dimethylamino) ethyl] phenyl-N-ethyl-N-methyl-carbamate (rivastigmine) or its pharmaceutically acceptable salts employing the novel intermediat...  
WO/2010/024775A1
There is provided a compound of Formula (I) or (II) and salts thereof wherein R1 is an imine or an alkylated imine, said imine or alkylated imine comprising a linear or branched alkyl group of length C1 to C5; R2 are each independently (...  
WO/2010/003046A3
The preparation and use of calcium, barium, magnesium and copper salts of gabapentin enacarbil are described.  
WO/2010/018676A1
A bactericide for agricultural and horticultural use containing an oxime ether derivative represented by formula (I) or at least one salt thereof. (In formula (I), X represents a halogen atom, a C1-20 alkyl group or the like; R1 and R2 e...  
WO/2010/018714A1
Disclosed is an amide derivative having excellent pest control effect, which is represented by general formula (1). In general formula (1), A represents a carbon atom, a nitrogen atom or the like; K represents a non-metal atomic group ne...  
WO/2010/018154A1
The present invention relates to a process for the production of (3aR, 4S, 7aR)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxyli c acid methyl ester (I), of carbamic acid (2-chloroethyl)(3-oxocyclohexyl)-alkyl ester enantiomers (I...  
WO/2010/015935A2
Disclosed herein are convenient, industrially advantageous and environmentally friendly processes for the preparation of cinacalcet hydrochloride. Disclosed also herein are novel hydrochloride, oxalate and di-p-toluoyl-L-(+)-tartrate sal...  
WO/2009/115537A8
The invention provides metal carbamates of the general formula (I) where R1 and R2 are each an alkyl group.  
WO/2010/013567A1
Disclosed is a pest control agent having an excellent effect, which contains, as an active ingredient, a compound represented by general formula (1). (In the formula, A represents a carbon atom, a nitrogen atom or the like; K represents...  
WO/2010/013666A1
Disclosed is a commercially novel method for producing a carbamate compound by using a carbonic acid ester and an amide compound in the presence of a basic compound, wherein the reaction speed is higher than those in the conventional met...  
WO/2010/010113A1
The present invention is directed to a process for the manufacture of compounds of formula IV wherein R1 is an amino protecting group, and R2 is hydrogen or C1-10 alkyl, comprising a) reacting a compound of formula Ia, wherein M+ is a ca...  
WO/2010/010174A1
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11 β-hydroxysteroid dehydrogenase...  
WO/2010/008312A1
The inventions relates to chemistry and medicine, in particular to antihypertensive agents and to the methods of the production thereof. The aim of said invention is to develop novel 1-alkyl-2-alkylcarbomoyl-glycerin derivatives which co...  
WO/2010/008886A2
Gabapentin prodrugs and intermediates thereof are described.  
WO/2010/008201A2
The present invention provides a UV-curable coating composition comprising an alkylene oxide-based urethane acrylate monomer and an optical fiber using the same, the optical fiber showing improved water resistance and excellent thermal, ...  
WO/2009/106237A3
The present invention pertains to a catalyst for the synthesis of organic alkyl carbamates, the method for preparing the same and the use thereof. The catalyst comprises a catalytically active component and a catalyst support, and the ca...  
WO/2010/007202A1
The invention relates to the enzymatic resolution of derivatives of cis- and trans-cyclopentane-1,2-diamines in order to obtain enantiomerically pure or enriched compounds, a method for preparing the starting materials for this method, t...  
WO/2009/109973A3
The present invention relates to novel fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as agents for the treat...  
WO/2010/004231A2
The invention relates to novel compounds having the following formula (I) in which: n is an integer from 1 to 12, in particular from 1 to 8, m and m' are, independently of one another, integers from 0 to 8, - q and q' are, independently ...  
WO/2010/006085A1
The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprisi...  
WO/2010/003046A2
The preparation and use of calcium, barium, magnesium and copper salts of gabapentin enacarbil are described.  
WO/2010/000856A1
The present invention relates to a method for producing substituted aminobiphenylene, in particular 2-aminobiphenylene, and a method for producing (het)acrylic acid amides of such aminobiphenyenes, in particular 2-aminobiphenyene.  
WO/2009/090251A3
The invention relates to a process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according ...  
WO/2009/154766A1
Disclosed are aspartic protease inhibitors represented by the following Formula: wherein R1 , R2, R3, R4, R5, R6, R7a, R7b and n are as defined herein, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising...  
WO/2009/151005A1
Disclosed is a method for efficiently producing an isocyanate compound at a low reaction temperature at a low reaction pressure without using a highly toxic phosgene and without going through a complicated process. Specifically, an isocy...  
WO/2009/147217A1
The present invention relates to compounds of formula (I) below in which: - R1 and R3 represent, independently of one another, a methoxy group optionally substituted by one or more fluorine atoms, - R2 and R4 represent, independently of ...  
WO/2009/146539A1
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing 4-(aminome...  
WO/2009/144179A1
The present invention relates to the compound L-menthyl-N-(2-hydroxyphenyl)carbamate, which is effective against body perspiration odor bacteria, in particular against armpit perspiration odor bacteria, and simultaneously effective as an...  
WO/2009/141170A2
The invention relates to a compound suited as entity carrier, having the general formula (I), wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier syst...  
WO/2009/141079A1
The invention relates to compounds and the synthesis of [F-18] labelled L-glutamic acid and [F- 18] labelled L-glutamate, to their derivatives according to formula (I) and to the uses thereof.  
WO/2009/139061A1
This invention provides a production process which, in producing an isocyanate without using phosgene, is free from various problems as seen in the prior art and can stably produce the isocyanate at a high yield for a long period of time...  
WO/2009/139373A1
Disclosed is a compound useful as an active ingredient of a pharmaceutical composition, such as a pharmaceutical composition for treating chronic renal failure and/or diabetic nephropathy. Extensive studies are made for the purpose of fi...  
WO/2009/138416A1
The present invention relates to new oxime carbamoyl derivatives of formula (I), processes for their preparation, and to pharmaceutical compositions containing them for the treatment of neurological disorders, such as neuropathic pain an...  
WO/2009/136365A1
The present invention relates to a process for the preparation of threo-3,4-epoxy-2- amino-1-substituted butane derivatives represented by general Formula I which comprises reacting compound of Formula III or salt thereof with an active ...  
WO/2009/130534A1
This invention relates to a process for synthesizing Atazanavir, Formula (I), including novel intermediates and novel steps to various intermediates along the synthetic pathway.  
WO/2009/129938A1
The present invention relates to substituted phenoxybenzamide compounds of general formula (I) : in which R1, R2, R3, R4, R5, X, R6 and q are as defined in the claims, to methods of preparing said compounds, to pharmaceutical composition...  
WO/2009/050365A3
The invention relates to a novel method for preparing (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin and the salts thereof. The invention is characterised in that it includes a step comprising the peptide coupling of 4 ...  
WO/2009/129181A1
This disclosure relates to novel propanediol-dicarbamates, their derivatives, pharmaceutically acceptable salts thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions...  
WO/2009/129532A1
Compounds useful for promoting lysosomal processes and thereby ameliorating the disruption of cellular and functional integrity induced by Aβ and other protein and glycoconjugate species are provided. Methods for the treatment of neurod...  
WO/2009/129387A2
Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.  
WO/2009/094577A3
Mesophasic forms of Ca-salts of (3S) -aminomethyl-5-hexanoic acids and methods of preparing and methods of using mesophasic forms of (3S) -aminomethyl-5-hexanoic acids are provided.  
WO/2009/094569A3
Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamates are disclosed. These carbamates can be coupled to drugs containing amines such as R-baclofen or S-pregabalin.  
WO/2009/119858A1
Disclosed is a novel benzene compound which has an excellent immunosuppressing activity, an excellent rejection-inhibiting effect and others, and is reduced in adverse side effects including bradycardia. Specifically disclosed is a compo...  
WO/2009/094563A3
A crystalline form of Ca-salts of (3S) -aminomethyl-5-hexanoic acids and methods of preparing a crystalline form of a (3S) -aminomethyl-5-hexanoic acid and methods of using a crystalline form of a (3S) -aminomethyl-5-hexanoic acid are pr...  
WO/2009/115538A1
The object of the invention is a method for producing urethanes through reaction of aromatic amines with a dialkyl carbonate, characterized in that the alkyl radical of the organic dialkyl carbonate has 2-18 carbon atoms and the reaction...  
WO/2009/115539A1
The object of the invention is metal carbamates of the general formula (I), where R1 and R2 are equal or different, and are an alkyl group with 1-18 carbon atoms and where M is an alkali metal atom.  
WO/2009/053443A3
This invention provides new indane compounds, their use for the treatment or prevention of melatoninergic disorders and its compositions.  
WO/2009/117095A1
The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are...  

Matches 551 - 600 out of 10,291