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Matches 351 - 400 out of 11,824

Document Document Title
WO/2011/044501A3
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q5, R1, R2, R3, Z1 and Z2 are as defin...  
WO/2011/044502A1
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, R1, R2 and R3 are as defined herein. ...  
WO/2011/039107A1
The invention relates to a method for the preparation for a crystalline form of 1-chloro-4-(Β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofura n-3-yloxy)-benzyl]-benzene. In addition the invention relates to a crystalline form obtainable b...  
WO/2011/038356A2
This invention provides novel liver targeting agents and their synthetic methods. A liver targeting agent, with a lysine based nitrilo triacetic acid structure as backbone which acquires multivalency with saccharide groups, to bind with ...  
WO/2011/035518A1
Pyrimidine derivatives and analogs, their pharmaceutically acceptable salts, processes for preparing them, pharmaceutical compositions comprising them, and their use in manufacture of medicaments for treating inflammatory and infectious ...  
WO/2011/029576A1
The present invention relates to a form of crystalline 4'-epidaunorubicin hydrochloride which is stable and readily soluble, and to a process for the production thereof. This process comprises crystallizing 4'-epidaunorubicin hydrochlori...  
WO/2011/025286A2
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invent...  
WO/2011/025286A3
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invent...  
WO/2011/017998A1
Gambogic acid cyclization analogues with formula I, II and III are disclosed, wherein cycles A, B and C are saturated or unsaturated alicyclic, alicyclic heterocyclic, aromatic ring or aromatic heterocyclic groups containing 4-10 members...  
WO/2011/018588A3
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an OSO3- or hydroxyl group, R3 is an alkyl, c...  
WO/2011/018587A3
The invention relates to FGF receptor-activating N-sulfate oligosaccharides having Formula (I), wherein R1, R4, R6, and R8 are -OSO3- or hydroxyl groups, R2 is an -O-alkyl group or a monosaccharide having Formula (II), R3 is a disacchari...  
WO/2011/019419A1
Tumors can be selectively targeted via compounds provided herein according to the formula, or a pharmaceutically acceptable salt thereof, wherein RA and RB are as defined herein. Tumors can be imaged or targeted for therapeutic treatment...  
WO/2011/016558A1
Disclosed is a method for easily and economically producing a highly pure glucosylceramide-containing material in a large amount from a plant material. A highly pure glucosylceramide can be obtained in a large amount by a method for prod...  
WO/2011/009987A3
Aureolic acid derivatives, the method for preparation thereof and the uses thereof. The present invention provides a bacterial strain that produces compounds belonging to the aureolic acid family, which can be used in the treatment of ca...  
WO/2011/006237A1
Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The thera...  
WO/2011/003876A1
Herein arc disclosed novel compounds according to Formula (I) and aggregates comprising such compounds. These aggregates arc useful to treat and prevent ocular infections caused by a vims, which virus binds to terminal sialic residues pr...  
WO/2011/000721A1
The present invention finds application in the field of medicine and, in particular, it relates to new compounds for the treatment and/or prevention of HIV; Ebola, Dengue, Hepatitis C, SARS or tuberculosis infections.  
WO/2010/149326A1
The present invention relates to a compound comprising an imine bond as an acid- labile trigger group, the use of such an imine bond as an acid-labile trigger group, a process of cleaving the imine bond in said compound, and a pharmaceut...  
WO/2010/139692A2
The present invention encompasses novel triterpene compounds of general Formula (I) wherein RN1, RN2, R11a, R11b, R4, R17, R19 and R20 are defined as in claim 1, which exhibit an antiviral effect and are therefore suitable for the treatm...  
WO/2010/139692A3
The present invention encompasses novel triterpene compounds of general Formula (I) wherein RN1, RN2, R11a, R11b, R4, R17, R19 and R20 are defined as in claim 1, which exhibit an antiviral effect and are therefore suitable for the treatm...  
WO/2010/138608A1
The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacolog...  
WO/2010/132777A3
A method for treating a urinary tract infection in a mammal in need thereof is disclosed, the method comprising administering to the mammal an effective amount of an antibacterial aminoglycoside compound.  
WO/2010/132765A2
Antibacterial compounds of structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2, R3, R11 are as defined herein. Methods associated with prepara...  
WO/2010/132839A3
The present invention provides new aminoglycoside dosing regimens associated with enhanced microbicidal activity and reduced nephrotoxicity, as well as methods of using these dosing regimens to treat various bacterial infections.  
WO/2010/132768A1
Antibacterial compounds of structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R11 and R12 are as defined herein. Methods associated with preparation and use o...  
WO/2010/132760A9
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 and R3 are as defined here...  
WO/2010/132768A9
Antibacterial compounds of structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R11 and R12 are as defined herein. Methods associated with preparation and use o...  
WO/2010/132759A1
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 or R3 are as defined herei...  
WO/2010/132839A9
The present invention provides new aminoglycoside dosing regimens associated with enhanced microbicidal activity and reduced nephrotoxicity, as well as methods of using these dosing regimens to treat various bacterial infections.  
WO/2010/132765A3
Antibacterial compounds of structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2, R3, R11 are as defined herein. Methods associated with prepara...  
WO/2010/132839A2
The present invention provides new aminoglycoside dosing regimens associated with enhanced microbicidal activity and reduced nephrotoxicity, as well as methods of using these dosing regimens to treat various bacterial infections.  
WO/2010/132759A9
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 or R3 are as defined herei...  
WO/2010/132777A2
A method for treating a urinary tract infection in a mammal in need thereof is disclosed, the method comprising administering to the mammal an effective amount of an antibacterial aminoglycoside compound.  
WO/2010/132760A1
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 and R3 are as defined here...  
WO/2010/132765A9
Antibacterial compounds of structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2, R3, R11 are as defined herein. Methods associated with prepara...  
WO/2010/126435A1
The present invention relates to novel compounds having an effect as i.a. galectin inhibitors, to the use of said compounds as a medicament as well as for the manufacture of a medicament for treatment of disorders relating to the binding...  
WO/2010/126888A1
Compounds, compositions and methods are provided for treating cancer and inflammatory diseases, and for releasing cells such as stem cells (e.g., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells i...  
WO/2010/118950A3
The invention relates to a method for producing unsaturated acylamidoalkyl polyhydroxy acid amides, in which the reaction product from polyhydroxy acid lactone and aliphatic diamine is reacted with the anhydride of a simple unsaturated c...  
WO/2010/118951A3
The invention relates to a method for producing monoethylenically unsaturated glycosylamines, in which an aldehyde sugar is reacted with a primary aliphatic amine or ammonia in an aqueous medium and with the anhydride of a simple unsatur...  
WO/2010/117803A3
The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesi...  
WO/2010/117803A2
The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesi...  
WO/2010/115935A1
The present invention relates to an improved synthesis of a trisaccharide of the formula, novel intermediates used in the synthesis and the preparation of the intermediates.  
WO/2010/115934A1
The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates.  
WO/2010/112649A1
The present invention is intended for use in the chemical industry and relates to a new enzymatic method for obtaining alpha-glycoside derivatives of resveratrol, in which a cyclodextrin glycosyltransferase (CGTase) is used, said CGTase ...  
WO/2010/113151A1
Provided herein are antimicrobial conjugates of two antibiotic agents, exhibiting improved activity also against resistant bacteria, compared to each of the agents separately or their mixture, and having substantially no resistance emerg...  
WO/2010/111777A8
Novel sodium channel blocking compounds tetrodotoxm galactopyranosides of formula I were isolated and purified by HPLC and identified further through IR, NMR, GC, and MS. The compounds have a galactopyranosyl moiety attached to C11 of te...  
WO/2010/111777A1
Novel sodium channel blocking compounds tetrodotoxm galactopyranosides of formula I were isolated and purified by HPLC and identified further through IR, NMR, GC, and MS. The compounds have a galactopyranosyl moiety attached to C11 of te...  
WO/2010/113960A1
Disclosed are: a thickening-inhibiting agent for inhibiting thickening of the peritoneal membrane by which thickening of the peritoneal membrane can be inhibited, prevented or treated with relieved side effects; and a dialysis solution w...  
WO/2010/111711A2
Provided herein are ganglioside synthesis inhibitors, including modulators of ganglioside glycosylation  
WO/2010/111711A3
Provided herein are ganglioside synthesis inhibitors, including modulators of ganglioside glycosylation  

Matches 351 - 400 out of 11,824