Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 351 - 400 out of 12,830

Document Document Title
WO/2014/070991A3
Provided herein are E-selectin antagonist therapeutic agents and improvements thereto and compositions comprising these E-selectin antagonists. Methods are also provided for using these E-selectin antagonist therapeutic agents to treat a...  
WO/2014/067995A1
The present invention relates to a method of preparation of α-galactosyl ceramides compounds of formula (I) comprising a step a) of glycosylation of a compound of formula (II) with a compound of formula (III).  
WO/2014/070709A1
Adjuvants comprising chitosan cross-linked with, an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-an...  
WO/2014/066274A1
The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degr...  
WO/2014/064161A1
The present invention concerns a process for the purification of tritium markedparomomycin ([3H]paromomycin), highly pure tritiated paromomycin obtained by said process and a composition comprising said paromomycin. The present invention...  
WO/2014/063441A1
The present invention relates to a use of a triterpene derivative of formula (I) for producing drugs which can be used for the prevention or treatment of influenza diseases, wherein the substituents are as defined in the specification. T...  
WO/2014/059740A1
Disclosed are a compound as shown in formula (I) and pharmaceutically acceptable salts thereof. R1, R2, R3, R4, R5, W, and n are defined as in the description of the present application.  
WO/2014/060408A1
The invention relates to compounds of the general formula (I) in which R1 is a hydrogen atom, a hydroxy or methoxy group, a halogen atom, or an NO2 group; R2 is a hydrogen atom, a hydroxy or methoxy group, or an acyl or aroyl group; R3 i...  
WO/2014/056038A1
The present disclosure provides a compound of the following formula, racemates, enantiomers, prodrugs and salts thereof: Formula (I). Also provided is the use of these compounds for the treatment of ischemia and reperfusion injuries. Fur...  
WO/2014/059220A1
The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceramides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions charact...  
WO/2014/055474A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. The invention also provides pharmaceutically acceptable compositions containing the compounds and methods of using the compositions...  
WO/2014/054601A1
The present invention aims at providing: a sugar derivative capable of producing a blue fluorescent color, which can be used for the imaging of a cell or an intracellular molecule; and a method for imaging a cell using the derivative. Th...  
WO/2014/053603A1
The invention relates to compounds of formula (I); wherein A and L are as defined in the description. The invention also relates to immunogens obtained from said compounds, and to antibodies raised against said immunogens. The compounds ...  
WO/2014/052457A1
Sweetener compositions comprising particular glycoside blends are described in this paper. The glycoside blends comprise any or all of rebaudioside A, rebaudioside B, and rebaudioside D together with stevioside in various proportions. Th...  
WO/2014/048439A1
The invention relates to a method for producing a glycoconjugate comprising an oligosaccharide part covalently linked to a non-sugar moiety selected from the group consisting of amino acids, peptides, proteins, lipids, longer alkyl group...  
WO/2014/044645A1
The patent application relates to compounds of formula (I) below: formula (I) to a process for preparing them and to the therapeutic use thereof.  
WO/2014/042087A1
Provided is a diarylethene compound having excellent water solubility. The diarylethene compound is represented by formula (I). [In formula (I), Sg is a monovalent saccharide residue formed by removing a hydroxy group from a saccharide c...  
WO/2014/043708A1
Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost immune function using a complex carbohydrate...  
WO/2014/034190A1
The present invention is a radiation-sensitive resin composition, which contains an acid-cleavable group-containing polymer, a radiation-sensitive acid generator and a solvent, and wherein the radiation-sensitive acid generator contains ...  
WO/2014/027203A1
An imaging agent comprising a conjugate of an oligosaccharide moiety with an imaging moiety. The oligosaccharide is Lewis A or Lewis B or a mimetic thereof, or a pharmaceutically acceptable salt or PEGylated form of Lewis A or Lewis B or...  
WO/2014/020285A1
The invention concerns novel glycosidase substrates of formula (I); in which R0, R1, R2, R3 and R4 are as defined in claim 1, and a method for detecting the presence of a catalytically active glycosidase by means of one of said substrates.  
WO/2014/021464A1
The purpose of the present invention is to provide: a novel KRN7000 analogue which is expected to have an immunosuppressive effect and is biased toward type-Th2;and a medicinal agent comprising the KRN7000 analogue. A compound represente...  
WO/2014/016361A1
The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections. Exemplary compounds are:  
WO/2014/016374A1
The present invention provides methods for purifying at least one saponin in a solution comprising the steps of: (a) providing at least one saponin in a first solvent comprising a solubilizing component; (b) replacing at least a portion ...  
WO/2014/017928A1
This invention relates to sphingoglycolipid analogues, compositions comprising these compounds, processes for preparing the compounds, and methods of treating or preventing diseases or conditions using the compounds, such as diseases or ...  
WO/2014/016317A1
The present invention relates to the synthesis of GPI-related surface antigens of the parasite Toxoplasma gondii (T. gondii) and the resulting products obtained. These synthetic compounds are suitable for diagnosis of toxoplasmosis, as w...  
WO/2014/013495A1
The present invention relates to amphiphilic aminoglycoside (AG) derivatives, especially derivatives of tobramycin, kanamycin A and paromomycin comprising hydrophobic side chains linked to the AG moiety by various linkers. These novel de...  
WO/2014/007362A1
Provided is a method whereby a target cyclic macrolide compound can be separated without using a silver compound even from a mixture that contains a compound having a double bond similar to the target cyclic macrolide compound. The metho...  
WO/2014/003950A2
Nutritional supplements are described comprising selenium containing nucleosides. Methods of making the nutritional supplements and using the nutritional supplements are also described.  
WO/2014/003950A3
Nutritional supplements are described comprising selenium containing nucleosides. Methods of making the nutritional supplements and using the nutritional supplements are also described.  
WO/2014/001204A1
This invention relates to carbamate-containing or thiocarbamate-containing galacto-pyranosyl compounds useful as therapeutic agents and being represented by the structural formula (II), wherein: X is O or S, R is selected from the group ...  
WO/2013/189237A1
Disclosed are a novel andrographolide derivative and analogue as well as a preparation method of the novel andrographolide derivative and analogue and an application to the treatment, the prevention and the relief on human viruses and ne...  
WO/2013/191550A1
The invention relates to the field of chemical derivatization. In particular, it relates to modified aminoglycosides, such as antibiotics, and methods for producing them. Provided is a method for the regioselective diazotation of a desox...  
WO/2013/191549A1
The invention relates to the field of carbohydrate chemistry. Provided is a process for the regioselective oxidation of a single secondary hydroxy function of a carbohydrate substrate comprising two or more secondary hydroxy functions, c...  
WO/2013/190103A1
The invention relates to a sialic acid derivative of formula (I), wherein the symbols have the meanings specified in the description, which is suitable for linking to a cargo for regulating metabolic processes, immune reactions, immuniza...  
WO/2013/188183A1
A rheology modifier which includes a mixture of short and long chain fatty acid esters is suitable for use in liquid surfactant-based compositions. A surfactant-based composition includes a surfactant, the rheology modifier, and water. T...  
WO/2013/182206A1
The application discloses a method for producing anomerically protected glycosidic oligosaccharide derivatives comprising the step of culturing, in a culture medium containing an anomerically protected lactose acceptor, a genetically mod...  
WO/2013/177985A1
A nitrogenous heterocyclic imide derivative having obvious insecticidal activity, and preparation method and uses thereof; the nitrogenous heterocyclic imide derivative and pharmaceutically acceptable salt thereof have been proved in pra...  
WO/2013/170985A1
The present invention relates to paromamine-/neamine-based compounds according to formula I or II having selective antimicrobial activity directed at ribosomal 16S RNA and lacking ototoxicity. Furthermore, the invention is directed to th...  
WO/2013/172640A1
The present invention relates to a pharmaceutical composition having a heat shock protein induction activity and comprising a compound isolated from Eucommia ulmoides. The compound isolated from Eucommia ulmoides according to the present...  
WO/2013/167751A1
The invention relates to a method for enhancing the biosynthesis and/or secretion of sapogenins in the culture medium of plant and microbial cellcultures. Further, the present invention also relates to the identification of novel genes i...  
WO/2013/162016A1
The purpose of the present invention is to provide a novel compound that is effective as an antitumor-active agent or a vaccine adjuvant, an intermediate useful in the synthesis of the compound, and a method for producing the same, as we...  
WO/2013/156858A1
Advantageous compounds and methods for preventing and/or treating viral infections are provided.  
WO/2013/152470A1
The present invention provides new ethyl salicylate glycosides compound, a synthetic method thereof, pharmaceutical compositions containing the ethyl salicylate glycosides compound, and applications of the ethyl salicylate glycosides com...  
WO/2013/152848A1
The present invention relates to fucose- and mannose-derived glycomimetics and their general use in prophylaxis or treatment of Pseudomonas aeruginosa infections including respiratory tract infections, urinary tract infections, nosocomia...  
WO/2013/149576A1
The present invention relates to a process of a chemically synthetic drug, and in particular, to a new intermediate of a heparin pentasaccharide and a preparation method thereof. The process has high reaction efficiency, and an easy reac...  
WO/2013/146555A1
The purpose of the present invention is to provide a method for producing a steviol glycoside. The present invention provides a method for producing a steviol glycoside. The present invention provides: a transformant having a steviol gly...  
WO/2013/143806A1
The present invention relates to enterococcal cell wall polymers and their uses in the prevention and therapy of bacterial infection.  
WO/2013/139344A1
3-O-Fucosyllactose is made by process which includes the hydrogenolysis of a new compound of the formula 1 wherein R1 and R2 are independently a group removable by hydrogenolysis, and R3 is a group removable by hydrogenolysis or H; or a ...  
WO/2013/141350A1
The purpose of the present invention is to provide an oligosaccharide with high versatility that can produce a protected sulfate oligosaccharide that can become a manufacturing intermediate of polysulfated hyaluronic acid, and to provide...  

Matches 351 - 400 out of 12,830