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WO/2018/145653A1 |
The present invention relates to the technical field of chemical medicine and relates to a compound represented by formula (I) or formula (II) and a preparation method therefor, the compound being a biaryl derivative and having retinoid-...
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WO/2018/148158A1 |
The present disclosure relates generally to catalyst materials and processes for making and using them. More particularly, the present disclosure relates to molybdenum, bismuth and iron-containing metal oxide catalyst materials useful, f...
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WO/2018/144869A1 |
Disclosed herein, inter alia, are compositions and methods useful for inhibiting ubiquitin-like modifier activating enzyme 5.
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WO/2018/144870A1 |
Disclosed herein, inter alia, are compositions and methods useful for inhibiting reticulon 4(RTN4).
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WO/2018/137260A1 |
Disclosed in the present application is a method for preparing a compound I, which is characterized in being prepared and obtained by reacting starting materials which comprise a compound II, which contains a carbon-carbon double bond, a...
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WO/2018/138369A1 |
The present invention relates to new malodour-counteracting agents of formula (I) or stereoisomers thereof, particularly useful in blocking the olfactory perception of androstenone, Formula (I), wherein R1, R2, R3,R4, R5, R6, R7 and X ha...
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WO/2018/134278A1 |
The present invention refers to a new process for the synthesis of (9β,10α)-pregn-4-ene-3,20-dione, commonly known as retroprogesterone, having the formula (1) shown below.
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WO/2018/129609A1 |
Compounds of formula (II) are useful in modulating voltage-gated sodium channel activity. Their preparation and use for reducing the severity of convulsant activity in a subject, for example in the treatment of epilepsy, is presented.
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WO/2018/120880A1 |
The present invention provides an insecticidal compound having an ether bond structure. The structural formula of the compound is as shown in formula A, wherein R1 is methyl, halogen atom, cyano group, or trifluoromethyl; R2 and R3 are H...
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WO/2018/121051A1 |
Disclosed is a preparation method for methyl 3-cyano-4-isopropoxybenzoate: step one, preparing methyl 3-aldehyde-4-hydroxybenzoate from methyl paraben; step two, preparing methyl 3-cyano-4-hydroxybenzonate from methyl 3-aldehyde-4-hydrox...
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WO/2018/121050A1 |
Disclosed in the present invention is a preparation method for 3-cyano-4-hydroxybenzoic acid methyl ester, comprising: step 1: preparing methyl 4-hydroxybenzoate into methyl 3-formyl-4-hydroxybenzoate; and step 2: preparing the methyl 3-...
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WO/2018/114464A1 |
This invention relates to a process for preparing electron deficient olefins, such as 2-cyanoacrylates, using an acid catalyzed two-step process including a transesterification reaction followed by a Knoevenagel condensation reaction.
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WO/2018/114458A1 |
This invention relates to a process for producing electron deficient olefins, such as 2-cyanoacrylates, using an acid catalyzed Knoevenagel condensation reaction.
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WO/2018/110669A1 |
Disclosed is a compound of formula (I): wherein all symbols are defined in the description. Also disclosed are pharmaceutical compositions comprising the compounds, methods of making the compounds, kits comprising the compounds, and meth...
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WO/2018/105572A1 |
The present invention is a method for producing ε-caprolactam via adipamide that serves as an intermediate. This method for producing ε-caprolactam is characterized by comprising a lactamization step wherein adipamide produced from a s...
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WO/2018/096176A1 |
A precursor compound of a fragrant aldehyde is provided, as well as a method of forming such a compound, a kit comprising said compound, and certain uses thereof. The precursor compound has formula (I), wherein A is a hydrocarbon residue...
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WO/2018/098270A1 |
The present disclosure relates to androgen receptor signaling inhibitors and the synthesis of the same. Further, the present disclosure teaches the utilization of the androgen receptor signaling inhibitors in a treatment for proliferativ...
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WO/2018/087767A1 |
The invention provides processes for the preparation of HU-910, which are scalable to industrial purposes, using safer reagents and having high yield and pure product and a crystalline structure of HU-910, which is a unique product thereof.
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WO/2018/083053A1 |
The present invention relates to fluoranthenyl-amine compounds according to a formula (I). Said compounds are suitable for use in electronic devices. The invention also relates to a method for producing said compounds, and to electronic ...
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WO/2018/078053A1 |
The invention relates to mRNA comprising lipid nanoparticles and their medical uses. The lipid nanoparticles of the present invention comprise a cationic lipid according to formula (I), (II) or (III) and/or a PEG lipid according to formu...
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WO/2018/074046A1 |
A purification method for acrylonitrile which comprises a purification step in which an acrylonitrile solution comprising acrylonitrile, hydrogen cyanide, and water is distilled, wherein the purification step comprises: a first step, whi...
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WO/2018/070165A1 |
The purpose of the present invention is to provide a measurement device that can quickly measure the concentrations of compounds in a reaction liquid for the purpose of easily producing a cyanohydrin-containing liquid that contains few r...
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WO/2018/070163A1 |
The present invention relates to: a production method for a lactonitrile-containing liquid; and a lactonitrile-containing liquid. The production method for a lactonitrile-containing liquid includes a step for reacting a cyanating agent w...
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WO/2018/070164A1 |
The purpose of the present invention is to provide a method for producing a cyanohydrin-containing liquid that has improved cyanohydrin yield. This production method for a cyanohydrin-containing liquid includes steps 1–4. Step 1: A ste...
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WO/2018/070166A1 |
The purpose of the present invention is to provide: a method that makes it possible to easily produce a cyanohydrin-containing liquid that contains few reaction raw materials or other impurities; and a device that is suited to the method...
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WO/2018/071327A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...
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WO/2018/071166A1 |
A catalytic composition and process useful for the conversion of an olefin selected from the group consisting of propylene, isobutylene or mixtures thereof, to acrylonitrile, methacrylonitrile, hydrogen cyanide and acetonitrile and mixtu...
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WO/2018/066447A1 |
A method for producing 1, 4-dicyanocyclohexane, which comprises a step for obtaining 1, 4-dicyanocyclohexane by subjecting a thermal concentrate of an ammonia aqueous solution of 1, 4-cyclohexane dicarboxylic acid to a cyanation reaction.
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WO/2018/063105A1 |
The present invention provides the methods of synthesis of [5]helicene compounds and the use of the said compounds conjugating with biomolecules to work as molecular reporter for diagnostic. The compounds in the present invention have th...
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WO/2018/062953A1 |
The present invention relates to a stilbene derivative and a method for preparing same. More particularly, the present invention relates to a novel stilbene derivative inhibiting a function of a cyclophilin and effective for preventing a...
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WO/2018/051928A1 |
The present invention is a method for producing an oxide catalyst that contains Mo, V, Sb and Nb, the method having a raw material mixing step of obtaining an aqueous mixed liquid that contains Mo, V, Sb and Nb, an ageing step of ageing ...
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WO/2018/053322A1 |
In one aspect, the disclosure relates to methods for preparation of terpene and terpene-like molecules. In a further aspect, the disclosure relates to the products of the disclosed methods, i.e., terpene and terpene-like molecules prepar...
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WO/2018/050554A1 |
The invention relates to cyanoethylated methylcyclohexane diamine (MCDA) and toluene diamine (TDA) derivatives, and the stereoisomers thereof of formula (I), to a method for producing same, and to the use of these compounds to produce po...
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WO/2018/038436A1 |
The present invention provides a novel diamine compound capable of producing a polymer which exhibits greatly enhanced mechanical properties and heat resistance while maintaining transparency. A film including a polymer produced using th...
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WO/2018/037321A1 |
Mesoporous graphitic carbon nitride (MGCN) materials and method of making said MGCN materials is described. The MGCN materials include a three dimensional cyanamide based carbon nitride matrix having tunable pore diameters, a pore volume...
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WO/2018/033467A1 |
The present invention discloses an efficient preparation of 3-amino-1-((2,6-di-substituted)phenyl)pyrazoles.
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WO/2018/030384A1 |
The present invention provides a method for producing an oxide catalyst containing antimony, which comprises a step (A) for obtaining an oxide catalyst with use of antimony particles containing diantimony trioxide as the antimony source,...
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WO/2018/025774A1 |
A process for producing an oxide catalyst containing Mo, V, Sb, and Nb, the process comprising: a raw-material preparation step comprising a substep (I) for preparing an aqueous liquid mixture (A) containing Mo, V, and Sb, a substep (II)...
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WO/2018/018091A1 |
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.
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WO/2018/015240A1 |
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.
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WO/2018/016611A1 |
Provided is a novel therapeutic agent for glaucoma, which has an sGC-activating activity. A therapeutic agent for glaucoma or an ocular hypotensive agent, which contains, as an active ingredient, a compound represented by formula (I-a) o...
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WO/2018/015489A1 |
Process for the preparation of a compound of Formula (I), the process comprising the reaction of a compound of Formula (II) with malononitrile in the presence of a base and a palladium catalyst, Formula (II) wherein X, Y and Z, independe...
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WO/2018/010932A1 |
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...
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WO/2017/217343A1 |
A method for manufacturing an ammoxidation catalyst having: a step (i) for preparing a raw material slurry containing molybdenum, bismuth, iron, and a carboxylic acid compound; a step (ii) for stirring the raw material slurry for 20 minu...
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WO/2017/213137A1 |
Provided is a novel agricultural/horticultural chemical for controlling pests in crop production such as agriculture and horticulture. An anilide compound or thioamide compound of a specific structure having a substituent shown by the fo...
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WO/2017/209297A1 |
A compound represented by general formula (2) [wherein R1 and R2 are as defined above; and X represents a halogen atom] is reacted in the presence of a palladium catalyst and a base. In this manner, it becomes possible to synthesize a tr...
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WO/2017/205019A1 |
A process provides for minimizing an amount of fuel gas utilized in an absorber off-gas incinerator and better control of emissions. The process provides for less temperature deviations in the absorber off-gas incinerator firebox and for...
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WO/2017/205425A1 |
Described herein are molecules for use in organic light emitting diodes comprising at least one moiety A, at least one moiety D, and at least one moiety B.
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WO/2017/205021A1 |
A process is provided for control of an ammoxidation reactor. More specifically, the process includes controlling an amount of oxygen added to the reactor, steam temperature and linear velocity to minimize reactor temperature deviations.
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WO/2017/202273A1 |
Disclosed in the present invention are a benzyl phenyl ether derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the present invention relates to a benzyl phenyl ether derivative re...
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