Heterocyclic Compounds

Matches 1,101 - 1,150 out of 5,408	< 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 >

Document	Document Title
WO/1995/032187A1	NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF A fused indan derivative represented by general formula (1), a pharmaceutically acceptable salt thereof, and an antitumor drug, wherein ring A represents an optionally substituted benzene or naphtalene ring, or a benzene ring having a lo...
WO/1995/031452A1	THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES Compounds of formula (I) wherein: Azo is alkyltetrazolyl or is chosen from the group consisting of oxadiazolyl, imidazolyl, pyrazolyl, triazolyl, oxazolyl, triazinyl, thiazolyl, isothiazolyl or any of these substituted; Y is an alkylene ...
WO/1995/030792A1	COMPOUNDS FOR CATIONIZING TEXTILE FIBRES, PROCESS FOR PREPARING THESE COMPOUNDS, AND PROCESS FOR FINISHING TEXTILE FIBRES The invention concerns compounds of general formula (I) for cationizing textile fibres, in particular cellulose-type and protein-type materials. In general formula (I), Y is the formula group (a) or (b), X is a borine or bromine atom; n ...
WO/1995/029902A1	SUBSTITUTED PHENYL AMINOSULPHONYL UREAS The invention relates to novel substituted phenyl aminosulphonyl ureas of formula (I) in which R1 and R2 have the meanings given in the description and R3 is possibly substituted triazinyl, and salts of the compounds of formula (I), in w...
WO/1995/029907A1	BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION This invention relates to a novel heterocyclic compound represented by formula (I), wherein X is O or S, Y is vinylene, or a group of formula: -NHCO-, -NHSO2-, -OCO-, -OCH2-, -NHCOCO-, -NHCOCH=CH-, -NHCOCH2-, -NHCONH- or (a) (wherein R6 ...
WO/1995/029900A1	CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS Compounds represented by formula (I), wherein ring A is benzene; Ar is aromatic group; R1, R2 and R3 each stands for H, acyl, hydrocarbon or heterocyclic, or R2 and R3, taken together, may form non-aromatic cyclic hydrocarbon; X is methy...
WO/1995/029898A1	HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF Herbicidal substituted hydroxybenzyl-heteroaryl compounds and derivatives thereof of formula (I) wherein Ar is a substituted or unsubstituted 5- or 6-membered heteroaryl group having 2 or 3 ring nitrogen atoms or a substituted or unsubst...
WO/1995/029899A1	ACYLATED AMINOPHENYLSULPHONYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS The invention concerns compounds of formula (I) and their salts, W1, W2, R, n, R1, R2, R4, X, Y and Z being defined as in claim 1 and R3 meaning an acyl residue. These compounds are suitable as herbicides and plant-growth regulators. The...
WO/1995/029901A1	FUNGICIDAL AZOLE DERIVATIVES Compounds having formula (1), wherein Q is (a) or (b); R1 is C1-C8 alkyl; R2 is C6-C18 aryl, unsubstituted or substituted with one or more C1-C6 alkyl, halo, C1-C6 alkoxy or C1-C6 haloalkyl; or C4-C17 heterocyclic aryl comprising one or ...
WO/1995/029672A1	HALOMETHYL AMIDES AS IL-1'beta' PROTEASE INHIBITORS Disclosed are compounds, compositions and methods for inhibiting interleukin-1'beta' protease activity, the compounds having formula (A) described herein.
WO/1995/029167A1	SUBSTITUTED CYCLOPROPYLCARBONYL-PHENYLAMINOSULPHONYL UREAS AS HERBICIDES The invention relates to novel substituted cyclopropylcarbonyl-phenylaminosulphonyl ureas of formula (I) in which the constituents R1, R2, R3 and R4 have the meanings given in the description and R5 is optionally halogen or C1-C4 alkyl-s...
WO/1995/029163A1	IMIDAZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME A novel imidazole derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, useful as excellent antihyperlipemic and antiarteriosclerotic, wherein R1 represents hydrogen or lower alkyl; n represents 0 o...
WO/1995/029175A1	ETHER COMPOUND AND USE THEREOF A novel ether compound represented by general formula (P-1) and a pest-controlling agent containing the same as the active ingredient, wherein R1, R2 and R3 represent each hydrogen, etc.; A represents a group represented by general formu...
WO/1995/028640A1	COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produc...
WO/1995/028374A1	PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE A novel glycerol derivative and a process for producing the same, and a process for producing a triazole derivative. Specifically the invention provides an optically active 2-arylglycerol derivative that is novel and useful as an interme...
WO/1995/027700A1	ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND A novel ether compound represented by general formula (P-1), a pest control drug containing the same as the active ingredient, and an intermediate for use in producing the same. In said formula, R1 represents halogen; A represents a grou...
WO/1995/026328A1	BIPHENYL DERIVATIVES AS 5HT1D ANTAGONISTS Compounds of formula (I), processes for their preparation and their use as CNS agents are disclosed, in which R1 is hydrogen, halogen, C1-6alkyl, C3-6cycloalkyl, COC1-6alkyl, C1-6alkoxy, hydroxy, hydroxyC1-6alkyl, hydroxyC1-6alkoxy, C1-6...
WO/1995/026343A1	NOVEL TRIAZOLE DERIVATIVE AND ANTIMYCOTIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT An antimycotic triazole derivative represented by general formula (I), a physiologically acceptable salt thereof, and an antimycotic agent containing the same as the active ingredient: wherein R1 and R2 represent each independently hydro...
WO/1995/025714A1	SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY A method for synthesizing enantionmerically enriched chemical intermediates with predetermined chirality is described. The method comprises formation of a pseudoephedrine amide, followed by stereoselective alkylation at the 'alpha' carbo...
WO/1995/025723A1	ANILIDE DERIVATIVES AS FUNGICIDES Compounds of formula (I), wherein: X is O or S; A is a 6 membered heteroaryl group comprising at least one nitrogen atom, which is optionally substituted by one or more of the group R2; R1 is alkyl, cycloalkyl, cycloalkenyl, alkenyl, alk...
WO/1995/025107A1	TRIAZOLE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF Novel triazole compounds of formula (I), and pharmacologically acceptable salts thereof, possess potent antifungal activities, and are useful for the treatment of fungal infections.
WO/1995/024381A1	CYANO COMPOUNDS AND PREPARATIONS THEREOF This invention relates to compounds of formula (I) which are useful as PDE IV inhibitors and for treating diseases related thereto.
WO/1995/024404A1	PREPARATION OF SYMMETRICAL AND UNSYMMETRICAL DITHIIN COMPOUNDS Novel 1,2-dithiin compounds useful as antifungal or anti-infective agents, as well as methods for their use as such, are described. The 1,2-dithiin compounds are particularly effective in treating infections, especially those caused by C...
WO/1995/024383A1	OXIME DERIVATIVES AND THEIR USE AS PESTICIDES New oxime derivatives are disclosed, as well as several processes for preparing the same and their use as pesticides.
WO/1995/024385A1	SULPHONAMIDE DERIVATIVES AS ASPARTYL PROTEASE INHIBITORS This invention relates to a novel class of sulfonamides that are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of aspartyl protease inhibitors characterized by specific structural and physicoche...
WO/1995/023507A1	INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES Compounds of structure (I), the corresponding N-oxides and agriculturally acceptable salts, are disclosed as effective insecticides, in which Q is selected from hydrogen, hydroxy, and fluorine; R is selected from a heteroaryl having 5 or...
WO/1995/023141A1	4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS This invention relates to certain 4-aminoquinazolines of formula (I) and the pharmaceutically acceptable salts and stereoisomers thereof wherein Z is: formula (II), formula (III), formula (IV) or formula (V) wherein X is methylene, thio,...
WO/1995/022966A1	HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF This disclosure relates to a novel class of hydroxamic and carboxylic acid based matrix metalloproteinase inhibitor derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of su...
WO/1995/022540A1	ENANTIOMERICALLY PURE (+)-LIAROZOLE This invention relates to the novel enantiomerically pure dextrorotatory isomer of liarozole of formula (I) and the pharmaceutically acceptable acid addition salt forms thereof. These compounds are particularly useful in treating disorde...
WO/1995/022546A1	INTRACELLULAR SIGNALLING MEDIATORS Therapeutic compounds with at least one carboxylic, acid, ester or amide-substituted moiety have the formula: TERMINAL MOIETY-(R)j. In the formula, j is an integer from one to three, the terminal moiety is an aliphatic chemical moiety or...
WO/1995/022541A1	ENANTIOMERICALLY PURE(-)-LIAROZOLE This invention relates to the novel enantiomerically pure laevorotatory isomer of liarozole of formula (I) and the pharmaceutically acceptable acid addition salt forms thereof. These compounds are particularly useful in treating disorder...
WO/1995/021526A1	USE OF 1,3,2-BENZODITHIAZOL-1-OXIDES AS MICROBIOCIDES FOR PROTECTING TECHNICAL MATERIALS, AND CERTAIN 1,3,2-BENZODITHIAZOL-1-OXIDES New and known 1,3,2-benzodithiazol-1-oxides having the formula (I) are disclosed, as well as their preparation and use for preventing technical materials from being affected by micro-organisms.
WO/1995/021832A1	PHARMACEUTICAL PIPERAZINE COMPOUNDS A diketopiperazine of formula (A), wherein one or both of R1 and R2, which may be the same or different, is: (I) X, or a phenyl group which is substituted by X, C(O)X, OC(O)CH2X, OCH2CH2X, CH2X, CONH(CH2)nX, O(CH2)nCH(OH) (CH2)nX or (a) ...
WO/1995/021813A1	CYCLOHEXANE DERIVATIVES AS VOLTAGE-GATED POTASSIUM CHANNEL BLOCKERS This invention concerns compounds of generic formula (I) or a pharmaceutically acceptable salt thereof, where the dotted line represents an optional bond, one of R1 and R5 represents hydrogen, C1-C6 alkyl, C7-C16 aralkyl, -(CHR6)nCHR7CN,...
WO/1995/021166A1	TRIAZOLE DERIVATIVES Triazole derivatives represented by formula (IIA), and salts and prodrug thereof, wherein R1 represents C1-6 alkoxy(C1-6)alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, C3-7 cycloalkyl(C1-6)alkyl, aryl, aryl(C1-6)alkyl, aryloxy(C1-6)...
WO/1995/021154A2	PHENYL ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND AGENTS CONTAINING THEM Phenyl acetic acid derivatives of formula (I) in which the substituents and index have the following meanings: X is oxygen or sulphur; R is hydrogen and alkyl; R1 is hydrogen and alkyl; R2 is cyano, nitro, trifluoromethyl, halogen, alkyl...
WO/1995/021167A1	TRIAZOLE DERIVATIVES A compound of formula (I), or a salt or prodrug thereof wherein R represents hydrogen or C1-6 alkyl, selective agonist of 5-HT1-like receptors and is therefore useful in the treatment of clinical conditions, in particular migraine and as...
WO/1995/020963A1	2-(2,3,5,6-TETRAFLUORO-4-PYRIDIL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND COMPOSITIONS AND METHOD OF USE THEREOF 2-(2,3,5,6-Tetrafluoro-4-pyridyl)-1,2-benzisothiazol-3(2H)-o ne 1,1-dioxides, pharmaceutical compositions containing them and methods for the treatment of degenerative diseases utilizing them.
WO/1995/020564A1	LEUKOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS Described are pharmacologically active leukotriene B4 derivatives of general formula (I) in which R1 is CH2OH, CH3, CF3, COOR4 or CONR5R6, R2 is H or an organic-acid group with 1 to 15 C-atoms, R3 is H, a C1-C14 alkyl group, optionally w...
WO/1995/019971A1	HALOGEN ALKENYL AZOLYL MICROBICIDES Novel halogen alkenyl azolyl derivatives of formula (I) in which R1 is possibly substituted alkenyl, possibly substituted cycloalkyl, possibly substituted aryl or possibly substituted heteroaryl, R2 is alkyl, halogen alkyl, 1-hydroxy alk...
WO/1995/019983A1	WATERSOLUBLE AZOLE ANTIFUNGALS A compound of formula (I), an acid or base addition salt thereof or a stereochemically isomeric form thereof, wherein A and B taken together form -N=CH-, -CH=N-, -CH2-CH2, CH=CH-, -C(=O)-CH2-, -CH2-C(=O); D is a radical of formula (D1), ...
WO/1995/018797A1	NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
WO/1995/018806A1	FLUOROPROPYLTHIAZOLINE DERIVATIVE AND HERBICIDE A fluoropropylthiazoline derivative represented by formula (1), a herbicide containing the same, and an intermediate for the synthesis of the derivative.
WO/1995/018792A1	PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS Novel pyrrolidine monomers bearing various functional groups are used to prepare oligomeric structures. The pyrrolidine monomers can be joined via standard phosphate linkages including phosphodiester, phosphorothioate, and phosphoramidat...
WO/1995/018789A1	PESTICIDES Compounds of formula (I) and the isomers, and isomer mixtures thereof, which are possible, in which either a) X is an N atom and Y is OR11 or N(R12)R13, or b) X is CH and Y is OR11, and in which furthermore: R11 is C1-C4alkyl; R12 and R1...
WO/1995/018097A1	ANTHRANILIC ACID DERIVATIVE An anthranilic acid derivative having a cGMP-PDE inhibitory activity and represented by general formula (I), or a pharmacologically acceptable salt thereof wherein R1, R2, R3 and R4 represent each independently hydrogen, halogen, hydroxy...
WO/1995/017397A1	FIBRINOGEN RECEPTOR ANTAGONISTS Fibrinogen receptor antagonists of formula (I) are disclosed for use in inhibiting the binding of fibrinogen to blood platelets and for inhibiting the aggregation of blood platelets, wherein G is (a) or (b).
WO/1995/017407A1	TETRAHYDROFURAN ANTIFUNGALS A compound represented by formula (I) wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy...
WO/1995/017408A1	SYNTHESIS OF DIARYL METHANES The present invention includes synthetic steps and intermediates involved in the reaction scheme a of converting compounds of formula (II) to the diarylmethanes of formula (I), wherein Y is oxygen or sulfur; A, B, C, D, and E are carbon ...
WO/1995/016007A1	POLYMERIZABLE CHIRAL COMPOUNDS AND THEIR USE The invention pertains to chiral compounds that contain at least one double or multiple bonded chiral group, at least one polymerizable group, at least one spacer and at least one mesogenic group, and to their use as polymerizable, chira...

Matches 1,101 - 1,150 out of 5,408	< 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 >