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Matches 1 - 50 out of 2,156

Document Document Title
WO/2022/153187A1
Methods for producing a compound of Formula I, Formula I, wherein R1 and R2 are independently a i) linear or branched or cyclic, ii) saturated or unsaturated, and iii) substituted or unsubstituted hydrocarbon group comprising 8 to 20 car...  
WO/2022/152109A2
Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nuc...  
WO/2022/148655A1
A fabric conditioner composition comprising; a) Ester linked quaternary ammonium compounds; and b) 0.1 to 30 wt.% perfume materials; wherein the ester linked quaternary 5 ammonium compounds comprise carbon chains derived from fatty acids...  
WO/2022/148673A1
Esterquats find major applications as fabric softeners. After Tallow fatty acids and Palm oil fatty acids, fatty acids from sustainable sources like Rice bran fatty acids (RBFA) are desired. RBFA is formed as a by-product during refining...  
WO/2022/121317A1
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...  
WO/2022/076507A1
The present disclosure relates to compounds that are capable of inhibiting PRMT8 and/or upregulating SirTl. The disclosure further relates to methods of treating neurodegenerative diseases and disorders (e.g., Alzheimer's disease).  
WO/2022/067446A1
Disclosed is a proteolipid vesicle (PLV) for delivering a therapeutic cargo, such as nucleic acids, polypeptides and molecules, to a cell, the proteolipid vesicle having a lipid nanoparticle comprising one or more ionizable lipids and on...  
WO/2022/063350A1
The subject of the present invention is a lipidoid of general formula (I), wherein X, Y, Z and R are as defined in the claims. This lipidoid is useful as a transfection agent. The invention further describes transfection agents, transfec...  
WO/2022/055267A1
The present specification relates to a method for preparing alkyl-D-alaninate, the method comprising a step for supplying an inert gas into a reaction solution when using aniline to synthesize alkyl-D-alaninate.  
WO/2022/015604A1
Personal care products, such as shampoos, conditioners, hair dyes, hair removal products, cleansers, cosmetics, mascaras, and toothpastes may be formulated to include one or more branched surfactants, from one or more surfactant classes,...  
WO/2021/244637A1
Provided herein is 2-(diethylamino) ethyl 2-(4-isobutylphenyl) propionate or pharmaceutically acceptable salts thereof. Furthermore, for use and methods in the treatment of various pains and inflammation, in particular osteoarthritis wit...  
WO/2021/234694A1
Lipid particles for nucleic acid delivery and clinical applications of same are provided. Accordingly there is provided a lipid particle comprising a cationic lipid encapsulating a nucleic acid sequence, wherein said nucleic acid sequenc...  
WO/2021/226020A1
Polymorphic forms of (R)-oxybutynin HC1, including three crystalline forms, are prepared and characterized. Uses of the various polymorphic forms of (R)-oxybutynin HC1 for Obstructive Sleep Apnea (OS A) treatment are also disclosed.  
WO/2021/221544A1
The invention relates to the field of organic chemistry and pharmacy and provides a novel compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2Н-chromen-2-on-7-yl sulphate, a method for treating and preventing f...  
WO/2021/222083A1
Clear, stable concentrated liquid compositions are disclosed that comprise from 30% to 90% by weight of an esterquat active, and from 10% to 50% by weight of a particular solvent system. The esterquat active is the quaternized reaction p...  
WO/2021/071033A9
The present invention relates to a method for preparing diethylamino hydroxybenzoyl hexyl benzoate and, specifically, to: a method for preparing diethylamino hydroxybenzoyl hexyl benzoate, which has a simple preparation process and can b...  
WO/2021/196777A1
The present invention belongs to the technical field of fine chemical engineering, and specifically relates to a polymerizable surfactant with reducibility and a preparation method therefor. The polymerizable surfactant with reducibility...  
WO/2021/196775A1
The present invention belongs to the field of polymer synthesis, and specifically discloses a reducing agent monomer for preparing a styrene-acrylic emulsion by means of oxidation-reduction at a normal temperature, and a synthesis method...  
WO/2021/156578A1
The invention relates to anti-UV molecules of natural origin, and to the process for the synthesis thereof and also the process for the synthesis of analogues thereof. More particularly, it relates to a two-step process for the synthesis...  
WO/2021/142062A1
Described herein are pharmaceutical compositions comprising one or more fumarate esters and methods for treating multiple sclerosis subjects with the compositions where the incidence of gastrointestinal side effects is reduced compared t...  
WO/2021/141969A1
Lipid nanoparticle compositions for delivery of nucleic acids are described. In various embodiments the lipid nanoparticle contains an ionizable lipid of the Formula (I). Methods of using such lipid nanoparticle compositions to achieve t...  
WO/2021/116608A1
The present invention relates to a process for the continuous synthesis of heavy alkyl acrylates by a transesterification reaction using hydrozincite as a heterogeneous catalyst.  
WO/2021/113260A1
Provided herein are compounds and pharmaceutical compositions useful as anticholinergic compounds. Also set forth herein are methods of treating subjects in need thereof, e.g., subjects suffering from hyperhidrosis, by administering the ...  
WO/2021/101508A1
Various salts of tranexamic acid esters compounds are described, along with compositions including such compounds. Methods of use for treatment of external surfaces (e.g. skin) and processes of producing the compounds and compositions ar...  
WO/2021/089030A1
Disclosed are the use of one or more lipid compounds in the delivery of nucleic acids, and a lipid-nucleic acid mixture, a pharmaceutical composition or a kit comprising the lipid compound and nucleic acids. The lipid compounds provided ...  
WO/2021/055835A1
The application relates to lipids of the general Formula (A) wherein at least one of the two side chains contains a carbonate functional group (M and/or M' is -0C(=0)0-) and to empty or loaded lipid nanoparticles (LNPs) including such li...  
WO/2021/026647A1
Disclosed herein is a lipid having a net charge at physiological pH, and being covalently attached to a lipid moiety. The lipid moiety comprises a hydrocarbon structure having two or more linked hydrocarbon chains, optionally having cis ...  
WO/2021/021634A1
Compositions for delivering nucleic acids to cells or tissue microenvironments are provided. In one embodiment, the compositions are lipid nanoparticle compositions formulated to have reduced splenic and hepatic clearance. It has been di...  
WO/2021/014368A1
According to one embodiment, there is provided a method of producing a gene modification T cell (CAR-T cells) which expresses a chimeric antigen receptor (CAR). This method includes stimulating a cell population containing a T cell with ...  
WO/2021/009374A1
The present invention relates to ionic liquid-type compounds having formula (I). The invention also relates to the use of such compounds for the dissolution and/or extraction of at least one compound of biological origin, such as a biopo...  
WO/2021/009274A1
The invention relates to an ethylene copolymer obtained by copolymerizing ethylene and an ion pair compound consisting of a cation of formula (I) and an anion selected from formulas (II), (III), (IV) and (V), wherein (I) where R1 = H or ...  
WO/2021/004947A1
The invention discloses a method for preparation of acetoacetate ester compounds with amino alcohol catalysts which are themselves diketenized in the course of the diketenization reaction; and subsequent polymerization of these acetoacet...  
WO/2020/254337A1
The invention concerns new quaternary ammonium compounds with surfactant properties and improved biodegradability.  
WO/2020/243217A1
Described herein are pH responsive compounds, micelles, and compositions useful for the detection of primary and metastatic tumor tissues. Compounds described herein are imaging agents useful for the detection of primary and metastatic t...  
WO/2020/243540A1
Disclosed are cationic lipids which are compounds of Formula I. Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly ca...  
WO/2020/230480A1
The present invention addresses the problem of providing: a polymerizable liquid crystal composition that can undergo uniform vertical alignment without a PI layer being provided, can inhibit occurrence of dropping marks or alignment irr...  
WO/2020/227322A1
Compositions comprising at least one esteramine active are disclosed in which the esteramine provides conditioning, softening, and/or cleaning properties. The compositions are useful for hair care, as well as in other applications, such ...  
WO/2020/218365A1
[Problem] To provide a curable composition which has excellent curability, preferably can contain water that is environment-friendly, can be cured into a cured film having excellent adhesiveness to a base material, particularly to a plas...  
WO/2020/219876A1
The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepa...  
WO/2020/154320A1
The present disclosure addresses elastomeric adhesives and elastomers that include a modified amine. The modified amine can be the reaction product of an amine with a Michael acceptor. The amine can be represented by H2N-Ar-R1-NH2, where...  
WO/2020/150384A1
Disclosed is a method of treating non-keratinous fibers using a composition comprising an amide and/or alkyl ammonium carboxylate salt wherein the treating method improves the robust performance of the non-keratinous fibers and simultane...  
WO/2020/145627A1
Provided is a method for preparing glufosinate, comprising the steps of: preparing a first intermediate compound by reacting L-homoserine in the presence of a first acid catalyst; preparing a second intermediate compound by reacting the ...  
WO/2020/118041A1
The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepa...  
WO/2020/087233A1
Disclosed is an application of an ionic iron (III) complex as a catalyst in preparation of a benzylamine compound, that is, an ionic iron (III) complex having a molecular formula of [(RNCHCHNR)CH][FeBr4] (R is tert-butyl) and containing ...  
WO/2020/075007A1
Provided is an addition-fragmentation agent of the formula (I) where Ramine comprises a tertiary amine group; R2 linking group of valence a+2; Z is an ethylenically unsaturated polymerizable group; and subscript a is 0 or 1.  
WO/2020/072324A1
The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for ...  
WO/2020/072605A1
The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepa...  
WO/2020/070403A1
The invention relates to the use of a stabilising compound comprising at least one N-oxyl compound and at least one polymerisation inhibitor other than an N-oxyl compound, for inhibiting transesterification catalyst degradation in a proc...  
WO/2020/031836A1
A polymerizable ionic liquid according to the present invention includes a compound comprising: an anion that has a predetermined structure and that includes a perfluoroalkyl group and a polymerizable functional group in the molecule the...  
WO/2020/023311A1
Processes for preparing neutral liposomes include adding a hydrophobic solution of liposome lipid bilayer precursors and a nucleic acid condenser to an aqueous composition of a nucleic acid condenser and a biologically active ingredient ...  

Matches 1 - 50 out of 2,156