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WO/1992/010509A1 |
Renin-inhibiting peptides of the cyclohexylstatin type having general formula (I), in which A, B, D, E, Y, R?1¿, R?2¿ and n have the meanings given in the description, are disclosed, as well as a process for producing the same and thei...
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WO/1992/003131A1 |
A class of heterocyclic amino-alcohol compounds is described for treatment of CNS-related diseases, namely, for use as a neuroprotective agent, to reduce neurotoxic injury associated with conditions of hypoxia, anoxia or ischemia which t...
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WO/1992/000276A2 |
There are disclosed compounds of formula (I): Z(CH2)nCHR1COOCHR2COOH, in which Z is -SR3, -COCHR4NHCOR5, (a) or -NHCHR7COOH; R4, R5, R6 and R7, which may be the same or different, are each phenyl or alkylphenyl C7-12; R1 is hydrogen, alk...
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WO/1991/017151A1 |
Compounds of formula (I), wherein R�1? is an electronegative substituent such as nitro, halogeno or cyano group and R�2? is a group selected from (Ia) and (Ib), wherein R is hydrogen, or an alkyl, cycloalkyl, aralkyl or aryl group, w...
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WO/1991/009027A1 |
This invention pertains to a novel group of Thiarubrine substances and closely related derivatives, useful as antifungal and antibiotic agents.
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WO/1991/007397A1 |
A thia- and/or selenafulvalenyl compound having an excellent thermal stability and represented by general formula (I), wherein X¿1? to X¿4? and X¿1?' to X¿4?' are each independently S or Se; Y is a substituent not inhibiting overlapp...
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WO/1991/005761A1 |
A method of inhibiting the growth or replication of viruses of the HIV group is disclosed. Also disclosed are compounds useful in the method and pharmaceutical formulations incorporating such compounds. The method involves the use of com...
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WO/1990/007521A1 |
The invention concerns novel renin-inhibitory peptides which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism, glaucoma and diseases caused by retroviruses. Processes for preparing the p...
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WO/1990/006304A1 |
The present invention provides compounds of formula (I), which contains between 9 and 27 carbon atoms, and wherein m and m1 are independently selected from 0, 1 and 2; R2a is hydrogen, methyl, or ethyl; R2b is acetylene or contains betwe...
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WO/1990/004918A2 |
Quaternary amine-containing ether lipid analogs of the formula R1-X-R2-N+(R3)(R4)(R5) Z- are disclosed. R1 represents a hydrophobic group and R2 represents the backbone of the molecule, with the quaternary amine being linked directly to ...
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WO/1989/008863A1 |
A non-linear optical material containing at least a compound represented by general formula (I) (wherein R1, R2, R3 and R4 each represents an organic substituent, provided that at least one of R1, R2, R3 and R4 is an electron-attracting ...
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WO/1989/003822A1 |
Anthralin analogues containing a thio-substituent, especially in one or more of the positions 2-, 7- and 10- of the anthralin ring. They may be made by reacting an anthralin derivative (e.g. 10-bromoanthralin) with a thiol or a compound ...
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WO/1989/001470A1 |
The invention concerns a process for producing E/Z mixtures of 2-(bicyclo[3.3.0]octane-3-ylidene) acetic acid derivatives of formula (I) in which either the E or the Z moiety predominates.
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WO/1988/008836A2 |
Certain aryl substituted naphthalene, benzoxepine, benzazepine and benzocycloheptene derivatives are disclosed. The compounds are useful in treating hyperproliferative skin disease, allergic reactions and inflammation.
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WO/1988/007514A1 |
Tolanes having the formula (I): R1-(A1-Z1)m-A3-C=C-A4-(A2)n-R2, in which R1, A1, Z1, m, A3, A4, A2, n and R2 are as given in claim (1), and application of said tolanes as components of liquid crystal phases, particularly as components of...
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WO/1988/005071A1 |
Dioxolanes, thio analogs thereof, and derivatives of these and methods of preparation. These materials are useful as additives in lubricants and fuels. Methods for reducing fuel consumption in internal combustion engines employing the lu...
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WO/1987/005781A2 |
Synergistic plant growth regulator compositions containing (i) an ethylene response or ethylene-type response inducing agent and (ii) a malonic acid derivative compound. This invention also relates to the use of said compositions for ind...
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WO/1987/005898A2 |
Method for retarding plant growth by applying to the plant an effective amount of a malonic acid derivative compound. This invention also relates to novel malonic acid derivative compounds and processes for the preparation thereof.
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WO/1987/005897A2 |
Malonic acid derivative compounds, processes for their preparation and their use for increasing crop yield.
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WO/1987/004349A1 |
A genus of novel peptide analogs which have potent renin-inhibiting activity, methods of treating renin-based hypertension using these compounds, and pharmaceutical compositions containing these compounds as active ingredients.
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WO/1987/004155A1 |
Hexasubstituted cyclokexane compounds have the formula (I), in which Z1 is -CO-X1-, -X1-CO-, -CH2-X2-, -X2-CH2- or -CH2- or - CH2-CH2-, Z2 has one of the meanings of Z1 or is a simple bond, Z3 is -X1-CO- or -X2-CH2- X1 is O, S or Se, X2 ...
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WO/1987/003581A1 |
Dispirotetradecane of formula (I), in which R1 and R2 are, independently of one another, alkyl with 1 to 12 C atoms, wherein also one or several non-adjacent CH2 groups may be replaced by -O-, -CO-, -CO-O-, -O-CO-, -O-COO-, and/or -CH=CH...
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WO/1987/001701A2 |
Nitrogen-containing heterocyclic compounds of formula (II) wherein R1 and R2 which signifie an alkyl group with 1 to 15 C atoms, wherein also one or several CH2-groups can be replaced by a grouping selected on the group -O-, -S-, -CO-, -...
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WO/1986/005486A1 |
Cyclohexane derivatives of formula R1-A1-Z1-A2-R2 in which R1 and R2 are in each case an alkyl group with 1-10 C atoms, in which also one or two non neighboring CH2 groups can be replaced by O atoms and/or -CO- groups and/or -CO-O- group...
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JP7454023B2 |
To provide a polythiol composition, a polymerizable composition for optical material and a preparation method for the same, from which an optical material is prepared to possess superior optical performance, high refractive index, high A...
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JP7201586B6 |
wherein Y1, Y2, Z, X1, X2, and W1 are defined in the specification. These compounds are useful in the treatment of tyrosine kinases, MAPK signaling pathway kinases and PI3K/AKT/mTor signaling pathway kinases-mediated diseases or conditio...
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JP7428810B2 |
Provided is a polymerizable composition including a compound represented by Formula (1), and an ultraviolet absorbing agent A having a maximum absorption wavelength on a shorter wavelength side than a maximum absorption wavelength of the...
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JP2023184176A |
To provide a mixture of a sulfur-containing compound that can yield a rubber composition having excellent reversion resistance, heat-aging resistance and over-cure resistance.The mixture of sulfur-containing compound of the present inven...
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JP2023177048A |
To obtain a resist pattern with improved resolution and good LER and fidelity.A chemically amplified negative resist composition contains: (A) an acid generator containing at least one selected from a sulfonium salt represented by the fo...
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JP2023546915A |
Described herein are compositions and methods for treating or preventing ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease, and other inflammatory diseases and/or infections in the anterior surf...
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JP7371699B2 |
A compound represented by the following formula (1):[wherein R1 represents a hydrogen atom or a methyl group; R2 represents an aromatic ring group optionally having a substituent or an alkyl group substituted with an aromatic ring group ...
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JP7356568B2 |
The present invention provides: an actinic ray-sensitive or radiation-sensitive resin composition, represented by specific general formula (1), containing (A) a resin, and (B) a compound that produces an acid when irradiated with actinic...
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JP7340617B2 |
The present invention addresses the problem of providing: a polymerizable liquid crystal composition which is used for the formation of an optically anisotropic film that exhibits excellent wet heat durability and excellent amine resista...
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JP2023098378A |
To provide a method that chemically synthesizes asparaptine readily and efficiently, and an asparagus acid ester compound useful for the method.The present invention provides a method for producing asparaptine (chemical name: (2S)-2-[(1,...
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JP2023097207A |
To provide a method for preparing asparagusic acid that suppresses the formation of polymers and is stable even when stored for a long time.The present invention provides a method for producing asparagusic acid by oxidizing dihydro aspar...
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JP7285226B2 |
To provide a polymerizable liquid crystal composition that is used for forming an optically anisotropic film excelling in all of reverse wavelength dispersibility, hygrothermal durability and amine resistance, and provide a compound, an ...
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JP7279162B2 |
Provided are an ultraviolet absorbing agent represented by General Formula (1) and an application thereof. In General Formula (1), R11 represents a monovalent substituent. n is 1 or 2. W1 and W2 each independently represent a hydrogen at...
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JP7252245B2 |
B, X1 and X2 represent N, O or S(O)n, R, Ra, Rb, Rc, Rd and IV represent radicals such as hydrogen, halogen, (C1-C6)-alkyl, (C1-C6)-alkyloxy and cyano.
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JP7207713B2 |
To provide a light storage material that stores light and allows the stored light to be taken out at any timing under control.A light storage material has a complex of a photosensitive aromatic compound, and one or more metal compounds s...
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JP7146159B2 |
The present invention relates to the field of compounds, and in particular to a probucol derivative, a preparation method therefor and use thereof, the probucol derivative having a structure represented by general formula I. The probucol...
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JP2022542183A |
The present invention provides a compound or pharmaceutically acceptable polymorphs, solvates, enantiomers, stereoisomers, prodrugs, hydrates and/or derivatives thereof, an effective amount of formula I, formula II, formula III , to phar...
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JP2022136035A |
To provide a metal nanoparticle complex that shows an affinity labeling function, a novel compound that has a great ability to modify metal nanoparticles constituting the complex, and a method for detecting a target molecule by using the...
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JP7067081B2 |
A resist composition comprising a base polymer and a quencher in the form of an iodonium salt of fluorinated aminobenzoic acid, fluorinated nitrobenzoic acid or fluorinated hydroxybenzoic acid offers a high dissolution contrast and minim...
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JP2022058376A |
To provide salts of lipoic acid choline ester (LACE) for use in the treatment of presbyopia, and a pharmaceutical composition including the same.The present invention discloses (R) lipoic acid choline ester tosylate (LACE tosylate), illu...
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JP2022058213A |
To provide a compound useful as a hole transport material for a photoelectric conversion element exhibiting photoelectric conversion efficiency allowing an electric current to be taken out efficiently, and a photoelectric conversion elem...
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JP7051133B2 |
The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, form...
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JP7041298B2 |
The present disclosure provides salts of lipoic acid choline ester (LACE), crystalline forms thereof, and methods of use thereof. The present disclosure further provides pharmaceutical compositions of LACE salts and methods of use thereof.
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JP7038437B2 |
Disclosed is a compound of formula I or a pharmaceutically acceptable hydrate, solvate, crystal, co-crystal, enantiomer, stereoisomer, polymorph or prodrug thereof, which is useful for treatment of eye disorders, skin diseases and/or com...
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JP7033223B2 |
An object of the present invention is to provide a polymerizable liquid crystal compound having excellent solubility, which is used for the formation of an optically anisotropic film having excellent durability, a method for producing th...
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JP7032161B2 |
To provide a salt and a resist composition capable of producing a resist pattern with a good focus margin (DOF).There are provided: a carboxylic acid salt represented by formula (I); an acid generator containing the salt; and a resist co...
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