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Patent Searching and Data


Matches 451 - 500 out of 4,263

Document Document Title
WO/1999/056699A2
The present invention relates to a method and catalysts for the stereoselective addition of a nucleophile to a reactive $g(p)-bond of a substrate. The chiral, non-racemic catalysts of the present invention constitute the first examples o...  
WO/1999/057089A1
A process for the production of enantiomerically pure or optically enriched sertraline-tetralone from a mixture containing two enantiomers using continuous chromatography. The chromatography comprises a liquid mobile phase comprising at ...  
WO/1999/052886A1
A method for kinetically resolving a stereoisomer mixture of compounds using asymmetric epoxidation is provided. Compounds contain an olefin moiety providing one stereoisomer to be epoxidized at a higher rate than the other stereoisomer ...  
WO1999042192A8
The invention relates to capillaries packed with particulate sorbents, having a constant inner diameter along the entire length. The bed of the sorbents is defined by hardened areas generated by thermal treatment. The invention especiall...  
WO/1999/047475A1
The invention concerns a method for separating $i((d/l)) and $i((meso)) diastereoisomers of bis-[1-phospha- 2,3-diphenyl- 4,5-dimethylnorbornadiene]. The invention also concerns a method for preparing optically active diphosphines of bis...  
WO/1999/047228A1
The invention concerns a method for separating from a mixture two optical isomers using a simulated mobile bed, consisting of an assembly of columns (C1,C2,C3,C4, C5,C6,C7,C8) divided into at least three successive zones (I, II, III). Sa...  
WO/1999/043668A1
Novel $g(b)-diketone compounds represented by general formula (3); and coordination compounds obtained by modifying the $g(b)-diketone compounds with a metal through coordination. The compounds can be easily synthesized. The compounds ca...  
WO/1999/042192A1
The invention relates to capillaries packed with particulate sorbents, having a constant inner diameter along the entire length. The bed of the sorbents is defined by hardened areas generated by thermal treatment. The invention especiall...  
WO/1999/038594A1
The invention relates to a method for separating substance mixtures by chromatography using spherical microparticles consisting of chemically and physically unmodified, water-insoluble, linear polysaccharides.  
WO/1999/021811A1
A method of separating optical isomers which permits optical resolution of compounds which have been incapable of satisfactory optical resolution under the conventional reversed-phase conditions. Specifically a method of separating optic...  
WO/1999/018052A1
A separating agent for optical isomers which has a high suitability for use as a reagent for optical resolution inherent in polysaccharide derivatives and also a solvent resistance and is capable of being produced through short process s...  
WO1998054228A3  
WO/1998/054228A2
This invention relates to molecularly imprinted polymers (MIPs) using an amide as the hydrogen bonding functional group. The amide MIPs made according to this invention exhibited enantiomeric recognition of the imprinted species when eva...  
WO/1998/049124A1
The invention relates to a novel method for producing enantiomer-free biarylketocarboxylic acids, whereby S-phenylethylamine is used as an auxiliary base in racemate resolution. Biarylketocarboxylic acids, specially substituted biaryl-4-...  
WO/1998/045230A1
The present invention describes the use of optically active polymers made from N-acryloyl-phenylalanine-neomenthylamide per se, in cross-linked form and/or bonded to a carrier, as stationary phases for chromatographic enantiomer separati...  
WO/1998/045240A1
A highly efficient method for enriching the chiral purity of a partially enriched mixture of enantiomers of an optically active compound, a major portion of the partially enriched mixture of enantiomers comprising a first enantiomer of t...  
WO1998024741A3  
WO/1998/029398A1
A process for preparing optically active piperazinecarboxylic acid derivatives by the resolution of diastereomeric salts wherein an optically active acidic amino acid derivative is used as the agent for optical resolution to thereby enha...  
WO/1998/024741A2
A process for the preparation of carbocyclic stereoisomers of formulae (I), (I'), (IIA'), (IIB'), (VA') and (VB'), including enantiomerically pure (IIA'), (I) and (I') utilising fractional crystallisation of salts formed with a chiral ba...  
WO/1998/023559A1
The invention concerns a method for splitting 1-amino-alkan-2-ol compounds of general formula (I) in which R can represent a large variety of alkyl groupings using as splitting agent one of the enantiomers R or S of N-tosyl-leucine.  
WO1998005640A3
A process for preparing a compound of formula (I), wherein R1 represents hydrogen or a protecting group; and R2 represents hydrogen or benzoyl optionally substituted in the phenyl moiety with halogen, methyl or C1-4 alkoxy; which process...  
WO/1998/018770A1
The present invention relates to a process for the preparation of (-)-3,4-trans-diarylchromans of formula (I), wherein R?1�, R?4� and R?5� are individually hydrogen, hydroxy, halogen, trifluoromethyl, C�1-6?alkyl, C�1-6?alkoxy ...  
WO/1998/013335A1
Process for the preparation of an inorganic salt of an optically active phenylglycine derivative, in which a diastereoisomeric salt of the optically active phenylglycine derivative and an optically active acid is treated with a strong in...  
WO/1998/008787A2
Described herein is a novel process to resolve a racemic compound into its optically active isomers without need for chemical transformation such as salt formation. The process advantageously utilizes polymers containing chiral moieties ...  
WO/1998/007671A1
The present invention is directed to the separation of optically active compounds into their respective enantiomers. The separation uses imprinted polymers having a desired structure and molecular memory for the corresponding print molec...  
WO/1998/005640A2
A process for preparing a compound of formula (I), wherein R�1? represents hydrogen or a protecting group; and R�2? represents hydrogen or benzoyl optionally substituted in the phenyl moiety with halogen, methyl or C�1-4? alkoxy; w...  
WO1997035841A3  
WO/1998/000425A1
A process for separating the enantiomers of a racemic mixture of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2H-pyrido [1,2-a]pyrazine comprising reacting the racemic mixture with D-(-) or L-(+) tartaric acid and separating the re...  
WO/1997/049733A1
The invention essentially relates to thermally crosslinked polysaccharide derivatives which contained no polymerizable functional groups prior to crosslinking and which are used in particular as support materials for the chromatographic ...  
WO1997047617A1
The invention relates to processes for the chromatographic separation of enantiomeric esters from 2-alkanoyl-chromane derivatives of the formula (I) in which Z is -(CH2)n1-(CHA)n2-(CH2)n3, where n1 = 0, 1, 2 or 3, n2 = 0 or 1, n3 = 0, 1,...  
WO/1997/046538A1
A process for producing D(+)-2-[4-(6-chloro-2-quinoxalyloxy)phenoxy]propionic acid, which comprises reacting an alkali metal salt of 4-(6-chloro-2-quinoxalyloxy)phenol with an alkali metal salt of L-2-chloropropionic acid in an aromatic ...  
WO/1997/043244A1
The invention relates to an improved process for the separation of racemic 2-)o-chlorophenyl)-2-methyl aminocyclohexanone (ketamine).  
WO/1997/041084A1
The invention relates to a process for the production of enantiomerically-pure AzeOH which comprises selective crystallisation of a diastereomerically-pure AzeOH-tartrate salt from a homogeneous solution of AzeOH, optically-active tartar...  
WO/1997/035841A2
A method for preparing optically substantially pure (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phe nyl]hydrazono]propanedinitrile from racemic 6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone intermediate is descri...  
WO/1997/033895A1
The invention relates to isolated RNA molecules with high affinity for particular amino acids, processes for isolating these, and uses thereof. Via a process which includes various washing and heating steps, one isolates these RNA molecu...  
WO/1997/028271A1
Specific optically active (S)-amines are obtained as follows: in a first stage, suitable racemic amines are allowed to react, in the presence of lipase from Candida antarctica and optionally in the presence of a diluting agent, with an e...  
WO/1997/021663A1
The disclosure relates to a process for obtaining optically active L-'alpha'-aminocarboxylic acids from the corresponding racemic D,L,'alpha'-aminocarboxylic acids. The following steps are involved: (a) the D,L,'alpha'-aminocarboxylic ac...  
WO/1997/012881A1
The invention pertains to a process for the continuous production of basic cyclic optically active 'alpha'-amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the resi...  
WO/1997/011927A1
Described is a method of resolving racemic mixtures of compounds of the formula (I) in which a, A, B, D, E, F, M, Q and R are as defined in the description. The method is carried out using prior art techniques but using the enantiomers o...  
WO/1997/004011A1
The invention relates to substantially photochemically cross-linked polysaccharide derivatives that do not contain photopolymerisable functional groups prior to the cross-linking, which can be used as carrier materials for the chromatogr...  
WO/1996/040617A1
A method of making (U)-3-(aminomethyl)-5-methylhexanoic acid that comprises condensing isovaleraldehyde with (II) to form primarily (III); reacting the (III) with a cyanide source to form (IV); decarboxylating the (IV) to form (V); hydro...  
WO1996033173A3  
WO/1996/037465A1
The invention relates to a chiral compound of general formula (I), wherein the groups R are the same or different but preferentially the same and are aliphatic C1-10 groups or optionally substituted aromatic groups or that both groups R ...  
WO/1996/037527A1
A suspension polymerization technique is provided for molecular imprinting based on the use of a perfluorocarbon liquid as the dispersing phase that does not interfere with the interactions between functional monomers and print molecules...  
WO/1996/036584A1
A process for the full or partial resolution of a mixture of enantiomers of a genus of chiral carboxylic acids is disclosed. The process uses a pure enantiomer of 1-aminoindan-2-ol as the resolving agent and achieves separation of the di...  
WO/1996/036606A1
New process for the preparation of ropivacaine hydrochloride monohydrate adapted for production in the plant, which process includes three steps.  
WO/1996/034842A1
There is provided a process for preferential conversion of a racemic 'alpha'-aryl propionic acid into an optically pure S-(+) or R-(-)-'alpha'-aryl propionic acid. An illustrative process is disclosed to prepare S-(+)-ibuprofen involving...  
WO/1996/033173A2
This invention relates to the preparation of racemic and enantiomeric 1-(pyridyl)-2-cyclohexylethylamine and, in particular, the separation of (+)-(S)- or (-)-(R)-1-(2-pyridyl)-2-cyclohexylethylamine from a racemic mixture of -1-(R,S)-(2...  
WO/1996/028402A1
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catal...  
WO/1996/027639A1
The invention relates to a process for the preparation of polysaccharide-N-arylcarbamates in suitable form as supports for chromatography, which process comprises adding to polysaccharide carbamates, which may be substituted in the aryl ...  

Matches 451 - 500 out of 4,263