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JP2862489B2 |
Sugar alcohol sulphate esters (I) and their salts are new: A = tris(hydroxymethyl)methyl or a gp. derived by removing the 1-OH gp. from a sugar alcohol or deriv., with ≥ 1 OH gp. in A being replaced by OSO3H; X = -NR<1>CO-; -NHCONH-; -...
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JP2840582B2 |
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JP2839468B2 |
O-Aryl methyl N-acyl or N-thioacyl hydroxylamine derivs. of formula ArCH2ON(R1)C(=X)R2 (I), their enantiomers and diastereoisomers are new. X = O or S; R1 = H, alkyl, cycloalkyl, cycloalkylalkyl, aryl, or arylalkyl; R2 = R21 or R22; R21 ...
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JPH10513194A |
There are provided novel compounds of formula I wherein D represents alkyl C1 to 6; T represents a C3-5 saturated or unsaturated alkylene chain substituted by -(CH2)m- NXY; -O-(CH2)z-NH- substituted by -(CH2)m-NXY; or -U-(CH2)a-N(X)-(CH2...
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JP2823368B2 |
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JP2823376B2 |
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JP2823060B2 |
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JP2819542B2 |
PURPOSE: To improve heat resistance and to thermally laminate by incorporating specific thiourea compound in developer contained in a recording layer provided in a thermal recording medium. CONSTITUTION: A recording layer of a thermal re...
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JP2799745B2 |
Compounds of formula (I) and pharmaceutically acceptable salts thereof: wherein a and b together form an -O- or -CH2- linkage or a bond; either Y is N and R2 is hydrogen; or Y is C-R1 wherein either one of R1 and R2 is hydrogen and the o...
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JP2799242B2 |
Certain substituted urea, thiourea, carbamate, and thiocarbamate compounds are potent inhibitors of the enzyme acyl-CoA: cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol, and ...
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JP2791156B2 |
Substituted ureas and thioureas are disclosed for use as high potency sweeteners.
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JPH10204025A |
To obtain the new compound capable of maintaining the normal activity of osteoclasts even in the hyperreactive syndromes of the osteoclasts and capable of being used for the treatments of osteoporosis, bone dispolism, malignant hyderpcal...
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JP2780876B2 |
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JPH10195037A |
To obtain a new phenol derivative capable of suppressing formation of foam cell of macrophage by excellent anti-oxidant action and ACAT inhibition action to suppress progress of arteriosclerosis, eliminating active oxygen and suppressing...
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JP2778450B2 |
PURPOSE: To obtain new compounds usable for treatment of disturbances in cardiac rhythm and prevention of sudden cardiac death caused by arrhythmia, and particularly suitable for treatment and prevention of diseases, in which arrhythmia ...
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JPH10505862A |
PCT No. PCT/SE95/01069 Sec. 371 Date Nov. 14, 1995 Sec. 102(e) Date Nov. 14, 1995 PCT Filed Sep. 20, 1995 PCT Pub. No. WO96/09286 PCT Pub. Date Mar. 28, 1996There are provided novel compounds of formula I I wherein D, R1, R2, R3, X and p...
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JP2747831B2 |
Titanocenes containing two 5-membered cyclodienyl gropus, for example cyclopentadienyl, and one or two 6-membered carbocyclic or 5- or 6-membered heterocyclic aromatic rings which are substituted by a fluorine atom in at least one of the...
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JPH1081659A |
To obtain the subject new fluorene derivative useful for chemoluminescent enzyme immunoassay as an enhancer of a chemoluminescent reaction of luminol with H2O2 using a peroxidase as a catalytic enzyme. This new fluorene derivative is exp...
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JP2734379B2 |
PURPOSE: To obtain a new compound useful as an organic developer or a stabilizer for a heat-sensitive recording sheet, having high sensitivity and excellent in heat, water and oil resistances. CONSTITUTION: This compound of formula I (A ...
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JPH1072429A |
To obtain a urea library compound useful as a lead compound for the development of chemicals by adding an amine reactant to each reaction zone containing liquid medium, adding and reacting an isocyanate reactant and adding a scavenger to...
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JPH1067743A |
To obtain a novel compound which is useful as a synthetic intermediate for a dihydropyridine derivative used in treatment of circulatory disorder and cardiovascular functional disorder. This compound is represented by formula I [R4 is a ...
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JP2717990B2 |
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JP2719841B2 |
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JP2701139B2 |
PURPOSE: To obtain a light-screening plate by mixing a transparent polymer- forming monomer with a metal salt of a phthalic acid deriv. represented by a specific formula and a thioamide deriv. or a thiourea deriv., and heat- polymerizing...
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JP2698933B2 |
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JP2696342B2 |
NEW MATERIAL:A compound expressed by formula I (R1 is H, phenyl, alkyl, naphthyl, etc.; R2 is H, alkyl, alkenyl, etc.; R3 is H, alkyl, alkynyl, etc.; R4 is H or alkyl; R5 is alkyl, aralkyl, etc.; m is 0 or 1; n is 0, etc.). EXAMPLE:N'-(2...
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JPH107647A |
To obtain the subj ect new compound having insulin secretion promoting action as well as insulin sensitivity increasing action, exhibiting selective β3 receptor stimulating action and useful for the treatment of diabetes. This thiourea ...
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JPH09512813A |
PCT No. PCT/GB95/01039 Sec. 371 Date Nov. 8, 1996 Sec. 102(e) Date Nov. 8, 1996 PCT Filed May 9, 1995 PCT Pub. No. WO95/30644 PCT Pub. Date Nov. 16, 1995Novel carbocyclic amides together with their salts, solvates and physiologically act...
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JP2686367B2 |
PCT No. PCT/US95/01641 Sec. 371 Date Aug. 31, 1995 Sec. 102(e) Date Aug. 31, 1995 PCT Filed Feb. 7, 1995 PCT Pub. No. WO95/21818 PCT Pub. Date Aug. 17, 1995A novel process for preparing clonidine derivatives has been discovered which is ...
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JP2684103B2 |
Composition containing a) a lubricant or a hydraulic fluid and b) at least one compound of the general formula I where x = 1 or 2 and, if x = 1, R has the meaning of R<1> or R<3>-O-, or, if x = 2, R has the meaning of R<8> and R<1> and R...
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JP2673890B2 |
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JPH09278737A |
To obtain a new phenol derivative having excellent lipid peroxidation suppressive activity and macrophage foaming suppressive activity, and useful for preventing/treating ischemic cardiopathy, etc., by reaction of a specific compound wit...
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JPH09278744A |
To obtain the subject new compound expressed by a specific formula, having a strong insecticidal action, especially exhibiting an excellent insecticidal action on injurious insects belonging to the order Lepidoptera or the order Coleopte...
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JP2663258B2 |
To obtain an aniline derivative useful as an intermediate for the production of a new benzamide derivative useful for the treatment and prevention of angina in mammals. This compound is expressed by R1-NH-A-NR3'-B-R4 (R1 is 3,4- dimethox...
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JPH09255665A |
To obtain a new compound having active-oxygen scavenging action and antioxidation action and effective for preventing the cell injury in arteriosclerosis, myocardial infarction and ischemia/reperfusion and suppressing arrhythmia, etc. Th...
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JPH09249628A |
To obtain the subject novel compound highly safe and excellent in suppressing action on lipid peroxidization, suppressing action on macrophage foaming, suppressing action on growth of LDL oxide, etc., useful as prevention or therapeutic ...
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JPH09227495A |
To obtain a novel phenol derivative which has excellent lipid peroxidation-inhibitory action, macrophage-foaming inhibitory action and oxidized low-density lipoprotein formation-inhibitory action with toxicity reduced, and is useful as a...
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JP2638347B2 |
PURPOSE: To attain developement having super contrast and excellent dot property at a relatively low pH in a short time by incorporating a specific aryl hydrazide in an assistant layer in contact with a silver halide emulsifying agent la...
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JPH09165368A |
To obtain thiourea derivative of plaunotol having excellent antiulcer action and antibacterial action against Hericobacter pyroli and useful for therapy and/or prevention of ulcerative disease. This compound is a thiourea derivative of p...
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JP2614893B2 |
There are described stable fluorescent labels comprising a complex of Eu<+><3> and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of Eu<+><3> and at least two heteroatom-con...
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JPH09504278A |
The use of an N-substituted urea derivative for the manufacture of a medicament for the treatment of a condition where there is an advantage in inhibiting the NO synthase enzyme, in particular cerebral ischemia, and pharmaceutical formul...
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JPH09104672A |
To obtain a hydroxamic acid derivative having a gelatinase-inhibiting action and useful for the therapy of rheumatism, etc. This compound of formula I [R1 is H, a 1-4C alkyl; R2 is H, a 1-8C alkyl, etc.; E is -CO-NR3 (R3 is H, a 1-4C alk...
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JP2598991B2 |
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JP2588729B2 |
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JPH0967336A |
To obtain the subject new compound expressed by a specific formula, presenting excellent Na+/Ca2+ exchange mechanism inhibitory action, reperfusion arrhythmia-suppressive action and reductive action on myocardial infarction foci, thus us...
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JPH09502170A |
Substituted phenethylamines of formula (I) useful for treating phosphodiesterase IV related disease states are disclosed herein.
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JP2582885B2 |
PCT No. PCT/HU88/00013 Sec. 371 Date Dec. 5, 1988 Sec. 102(e) Date Dec. 5, 1988 PCT Filed Mar. 8, 1988 PCT Pub. No. WO88/06841 PCT Pub. Date Sep. 22, 1988.The invention relates to synergistic combinations of known fungicide active ingred...
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JPH09501651A |
PCT No. PCT/GB94/01325 Sec. 371 Date Mar. 18, 1996 Sec. 102(e) Date Mar. 18, 1996 PCT Filed Jun. 20, 1994 PCT Pub. No. WO95/00505 PCT Pub. Date Jan. 5, 1995Compounds of formula (I) and salts, esters and amides thereof, wherein R1 is a C1...
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JPH09500885A |
New medicaments containing (thio)carbamidinic acid derivatives having formula (I) are disclosed, as well as new (thio)carbamidinic acid derivatives, a process for preparing the same and medicaments containing these compounds. Medicaments...
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JP2574436B2 |
New substituted benzoyl(thio)ureas of the formula (I), in which Q stands for oxygen or sulphur, R<1> stands for hydrogen, halogen, nitro, methyl or trifluoromethyl, R<2> stands for hydrogen, fluorine or chlorine, R<3>< >stands for hydrog...
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