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JP2007502306A |
The present invention relates to 1,3-oxathiolane-2-thione compounds of the general formula (I): wherein R<1> and R<2> are the same or different, each of which denotes a straight-chain or branched alkoxy residue with 1 to 6 carbon atoms o...
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JP2007001982A |
To provide a method for screening a substance for the ability to exert an influence on the formation of a retinoid X receptor homodimer comprising a step for combining the substance and a solution containing retinoid X receptors and a st...
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JP3844978B2 |
To produce an analog of BCH-189 from a less expensive precursor. A method for resoluting the enantiomers of a nucleoside of the formula (wherein, Y is H or fluorine; and R is an acyl). The method includes a process treating a nucleoside ...
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JP2006290883A |
To provide a new substituted heterocycle carboxylic anilide derivative which can control insect pests having resistance against existing chemicals on the production of crops for agriculture, horticulture and the like.This substituted het...
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JPWO2004108129A1 |
The present invention comprises an agent for preventing blood vessel wall invasion of bone marrow-derived vascular stem cells or inflammatory cells containing a phthalein pigment compound as an active ingredient, an agent for preventing ...
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JP2006188449A |
To provide a method for producing a cyclic disulfonic acid ester, having a high reaction rate, capable of giving the ester at a lower cost than ever, and therefore industrially advantageous.This method for producing the cyclic disulfonic...
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JP2006515322A |
A process for the preparation of benzo[d]isoxazol-3-yl-methanesulfonic acid of formula (I), or a salt thereof, and the intermediates thereof, useful as an intermediate in the preparation of zonisamide.
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JP2006515274A |
Methods for regulation of lipid and cholesterol uptake are described which are based on regulation of the expression or function of the SR-BI HDL receptor. The examples demonstrate that estrogen dramatically downregulates SR-BI under con...
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JP3761552B2 |
To provide a method for producing a polysulfide compound under anhydrous reaction conditions. The method for producing the polysulfide compound comprises carrying out a reaction between a dihalogen compound of formula(I):X-R-X[ wherein, ...
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JP3760540B2 |
To provide a lithium secondary battery electrolyte having a small capacity reduction effected together with a progress of a charge and discharge cycle progresses. This electrolyte contains lithium salt as a solute, a cyclic sulfuric este...
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JP3759965B2 |
Compounds of formula (I): in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R2 and R3 represent, in particular, H or alkyl, or R2 and R3, taken toget...
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JP2006508147A |
The invention provides lapachone analogs and derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can a...
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JP2006056903A |
To provide a pharmaceutical product effective for treatment of skin disease.The pharmaceutical product contains a compound of formula (II) or (III) or a salt, an optical isomer or a geometrical isomer thereof.
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JP2006036770A |
To selectively inhibit virus (particularly influenza virus), especially glycolytic enzymes like neuraminidase, above all, viral or bacterial neuraminidase.Novel compounds of Formula (III) or Formula (IV) are described. The compounds gene...
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JP2005536469A |
This invention relates to novel oxathiinecarboxamides of the formula (I) in which R, R1 and m are as defined in the disclosure, to a plurality of processes for preparing these substances and to their use for controlling unwanted micro-or...
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JP3718722B2 |
A composition for reducing a copper oxide layer to metallic copper so as to facilitate bonding a resin to the metallic copper is disclosed. The composition is an aqueous reducing solution containing a cyclic borane compound. Examples of ...
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JP2005535669A |
The present invention relates to novel macrocycles of the general formula (I) and to the use thereof in the treatment of cancer diseases.
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JPWO2004002973A1 |
Efficiently and industrially advantageous for optically active 1-substituted amino-2,3-epoxypropane, which is made from optically active 1-substituted amino-2,3-propanediol and is useful as a manufacturing intermediate for agricultural c...
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JP3707760B2 |
To provide an information recording medium for recording information with a visible laser light having high recording sensitivity, high light-fastness and low error generation rate and an information recording method. A recording layer c...
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JP3707759B2 |
To enable recording characteristics to be maintained over a long period of time and at the same time, especially improve the stability of light resistance by adding either of coloring matter compounds expressed by two different types of ...
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JP2005281241A |
To provide a sulfur atom-containing cyclic compound containing atomic sulfur in a high density and thus useful for optical materials, and to provide a method for production thereof.This sulfur atom-containing cyclic compound comprises a ...
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JP2005272452A |
To provide a new agricultural chemical, particularly an insecticide or acaricide.This invention relates to a substituted benzanilide compound represented by general formula (1) [wherein G is a ring such as G-7, G-13, G-71 or the like; W1...
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JP3704055B2 |
To obtain a new intermediate useful for a method for diastereoselective synthesis for preparing optically active cis-nucleosides, nucleoside analogs and derivatives. This intermediate is represented by the formula (I), wherein, W and X a...
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JP2005520791A |
Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders suc...
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JP3660890B2 |
To provide an acid anilide derivative having an improved fungicidal effect, especially an improved effect for suppressing botrytis fungi, compound to those of nicotinanilides such as 2-chloronicotinic acid-2'-ethylanilide or 2- chloronic...
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JP3657523B2 |
To obtain an acid anilide derivative more improved in bactericidal action, especially more improved in a controlling effect on Botrytis, when compared with conventional nicotinic acid anilides, such as 2-chloronicotinic acid 2'-ethylanil...
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JP2005119987A |
To provide an ACC activity inhibitor which is effective for treating hyperlipemia induced by obesity and fatness, impaired glucose tolerance estimated to be based on fatty liver and insulin resistance, diabetes, diabetic complication (di...
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JP2005113118A |
To provide a polymer for a photoresist having high transmittance, etching resistance, thermal resistance, adhesiveness and low light absorbance, and high affinity for a developer in order to obtain a pattern improved of LFR (line edge ro...
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JP2005508380A |
This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A4 analogs of the following formulas (I) and (II): wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating infla...
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JP2005504777A |
Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1 and T2 are each independently selected from the group consisting of O, NR, and CH2, where R-H or C...
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JP2005035964A |
To provide a new agrochemical, especially insecticide or acaricide.The invention provides a substituted benzanilide compound expressed by general formula (1) [G is a ring such as G-7, G-13 or G-17; W1 and W2 are each independently oxygen...
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JP2004535428A5 |
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JP2004531474A |
Symmetrically disubstituted aromatic compounds and pharmaceutical compositions containing such compounds that inhibit and/or modulate the activity of poly(ADP-ribose) glycohydrolase, also known as PARG, are described. The invention is al...
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JP3548967B2 |
Sulfonium compounds of the formula 1 or 2 are described: in which R denotes a mononuclear cycloalkyl radical having 3 to 8 ring carbon atoms or a mononuclear cycloalkyl radical having 3 to 8 ring carbon atoms to which at least one furthe...
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JP2004522708A |
The present inventors have found that the contrasting chemical, physical and environmental characteristics of alpha and beta endosulfan provide an opportunity to formulate an effective endosulfan formulation with lower risk to the enviro...
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JP2004168706A |
To provide a bactericidal or insecticidal agent for agriculture and horticulture which is highly effective even when used in a small amount and which is highly safe for object crops.A phenyl carbamate compound represented by formula (1) ...
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JP2004159664A |
To provide a method of screening a substance for an ability to effect the formation of a retinoid X receptor homodimer comprising combining the substance and a solution containing the retinoid X receptor and determining the presence of h...
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JP2004149543A |
To provide a enantiomerically pure dioxolane nucleoside having excellent anti-HIV activity.The method and a composition for therapeutic treatment of an infected human with HIV (human immunodeficiency virus) include administration of an H...
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JP3530150B2 |
To obtain BCH-189 analog from an inexpensive precursor. This compound is represented by the formula (R is selected from hydrogen, an alkyl group, a silyl group and an acyl group) and is enriched with an enantiomer.
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JP3519736B2 |
A method and composition for the treatment of humans infected with HIV that includes administration of an HIV treatment amount of an enantiomerically pure beta -D-dioxolanyl purine nucleoside of formula (I), wherein R is OH, Cl, NH2, or ...
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JP2004511502A |
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...
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JP2004511501A |
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...
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JP3506707B2 |
A method for the removal, separation, and concentration of alkali metal, alkaline earth metal, Pb and/or Tl cations from a source solution which may contain larger concentrations of other ions comprises bringing the source solution into ...
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JP2004507523A |
A compound of general formula (I) wherein R<1> and R<2> are H, C1-C6alkyl or (CH2)d(C3-C6cycloalkyl) wherein d = 0, 1, 2 or 3; or R<1> and R<2> together with the nitrogen to which they are attached from an azetidine ring; Z or Y is -SR<3...
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JP2004002250A |
To provide a fungicidal insecticide which is used for agriculture and horticulture, has a high potency at a low dose, and has high safety for target crops.This heterocyclic iminophenyl compound represented by the formula [A is a heterocy...
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JP2003531824A |
Novel derivatives of prostaglandin compounds of the F-series (PGF), specifically macrocyclic internal 1,15-lactones of fluprostenol and related PGF analogs, such as cloprostenol or latanoprost. The novel analogs can be formulated into op...
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JP3457240B2 |
To provide a method for producing an episulfide compound by epithioation of the corresponding epoxy compound in high yield in such a way that the product episulfide compound does not run to tar. This method for producing an episulfide co...
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JP3452086B2 |
A process for the preparation of perfluoroalkoxy(alkythio)benzenes from perfluorochloroalkoxy(alkythio)benzenes with hydrogen fluoride in the gas phase and in the presence of a catalyst.
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JP2003267968A |
To provide a photo acid generator, one component of a chemical amplification photo resist which has spectral sensitivity in the visible light region, especially argon laser light (488 nm or 514 nm) and can improve workability.A photosens...
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JP3426241B2 |
Compositions are disclosed comprising (a) a metal chelate wherein the metal is selected from the group consisting of europium, terbium, dysprosium, samarium osmium and ruthenium in at least a hexacoordinated state and (b) a compound havi...
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